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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2026-176</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-10168</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДРУГИЕ ПРОБЛЕМЫ ЭНДОКРИНОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OTHER PROBLEMS OF ENDOCRINOLOGY</subject></subj-group></article-categories><title-group><article-title>Эктопированная аденома околощитовидной железы как причина персистирующего первичного гиперпаратиреоза (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Ectopic parathyroid adenoma as a cause of persistent primary hyperparathyroidism (case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0027-1786</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булгакова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulgakova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Булгакова Светлана Викторовна, д.м.н., доцент, заведующая кафедрой эндокринологии и гериатрии </p><p>443099, Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Svetlana V. Bulgakova, Dr. Sci. (Med.), Associate Professor, Head of the Department of Endocrinology and Geriatrics </p><p>89, Chapaevskaya St., Samara, 443099</p></bio><email xlink:type="simple">s.v.bulgakova@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-7282-2416</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анисимов</surname><given-names>С. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Anisimov</surname><given-names>S. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анисимов Святослав Олегович, студент Института клинической медицины </p><p>443099, Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Svyatoslav O. Anisimov, Student, Institute of Clinical Medicine </p><p>89, Chapaevskaya St., Samara, 443099</p></bio><email xlink:type="simple">soa03072003@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6243-6528</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мерзлова</surname><given-names>П. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Merzlova</surname><given-names>P. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мерзлова Полина Ярославовна, ассистент кафедры эндокринологии и гериатрии </p><p>443099, Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Polina Ya. Merzlova, Assistant of Department of Endocrinology and Geriatrics </p><p>89, Chapaevskaya St., Samara, 443099</p></bio><email xlink:type="simple">p.ya.merzlova@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6628-7718</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Емелина</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Emelina</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Емелина Алсу Фиркатовна, врач-эндокринолог </p><p>432008, Ульяновск, ул. Лихачева, д. 12</p></bio><bio xml:lang="en"><p>Alsu F. Emelina, Endocrinologist </p><p>12, Likhachev St., Ulyanovsk, 432008</p></bio><email xlink:type="simple">ildar.93@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8827-4919</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаронова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharonova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шаронова Людмила Александровна, к.м.н., доцент кафедры эндокринологии и гериатрии </p><p>443099, Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Lyudmila A. Sharonova, Cand. Sci. (Med.), Associate Professor of Department of Endocrinology and Geriatrics </p><p>89, Chapaevskaya St., Samara, 443099</p></bio><email xlink:type="simple">l.a.sharonova@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6678-6411</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгих</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgikh</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Долгих Юлия Александровна, к.м.н., доцент кафедры эндокринологии и гериатрии </p><p>443099, Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Yulia A. Dolgikh, Cand. Sci. (Med.), Associate Professor of Department of Endocrinology and geriatrics </p><p>89, Chapaevskaya St., Samara, 443099</p><p> </p></bio><email xlink:type="simple">yu.a.dolgikh@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-4531-9682</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Косарева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kosareva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Косарева Ольга Владиславовна, к.м.н., доцент кафедры эндокринологии и гериатрии </p><p>443099, Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Olga V. Kosareva, Cand. Sci. (Med.), Associate Professor of Department of Endocrinology and geriatrics</p><p>89, Chapaevskaya St., Samara, 443099</p></bio><email xlink:type="simple">o.v.kasareva@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самарский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Центральная клиническая медико-санитарная часть имени заслуженного врача России В.А. Егорова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Egorov Honored Doctor of Russia Central Clinical Medical and Sanitary Unit</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>25</day><month>06</month><year>2026</year></pub-date><volume>0</volume><issue>7</issue><fpage>58</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Булгакова С.В., Анисимов С.О., Мерзлова П.Я., Емелина А.Ф., Шаронова Л.А., Долгих Ю.А., Косарева О.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Булгакова С.В., Анисимов С.О., Мерзлова П.Я., Емелина А.Ф., Шаронова Л.А., Долгих Ю.А., Косарева О.В.</copyright-holder><copyright-holder xml:lang="en">Bulgakova S.V., Anisimov S.O., Merzlova P.Y., Emelina A.F., Sharonova L.A., Dolgikh Y.A., Kosareva O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/10168">https://www.med-sovet.pro/jour/article/view/10168</self-uri><abstract><p>Персистирующий первичный гиперпаратиреоз (ПГПТ) после паратиреоидэктомии чаще всего обусловлен эктопией патологически измененной околощитовидной железы (ОЩЖ). Это состояние делает точную предоперационную топическую диагностику критически важной, особенно при повторных вмешательствах, которые сами по себе сопряжены с повышенным риском осложнений из-за рубцовых изменений и сложностей анатомической идентификации. В представленном клиническом наблюдении у пациента 70 лет сохранялись биохимические признаки ПГПТ после первоначальной операции. Во время того вмешательства было удалено образование, которое, по данным визуализации, соответствовало аденоме ОЩЖ, но послеоперационная гистология неожиданно выявила папиллярный рак щитовидной железы (ЩЖ). Эта диагностическая дилемма наглядно иллюстрирует морфологическое сходство различных образований шеи при интраоперационной ревизии и подчеркивает ценность интраоперационного гистологического исследования в сомнительных ситуациях. Для выявления причины персистенции заболевания было проведено комплексное обследование. Повторная сцинтиграфия с ОФЭКТ/КТ и мультиспиральная компьютерная томография (МСКТ) позволили точно локализовать патологический очаг. Диагностирована эктопированная аденома правой нижней ОЩЖ с патологической миграцией, соответствующая типу С по классификации Perrier, которая впоследствии была успешно удалена. Данный случай подтверждает необходимость мультидисциплинарного подхода и высокой онкологической настороженности при ведении пациентов с ПГПТ. Он также демонстрирует практическую пользу классификаций эктопии ОЩЖ, которые не только систематизируют анатомическую локализацию, но и помогают хирургу прогнозировать техническую сложность предстоящего вмешательства, потенциальные риски и выбрать оптимальный хирургический доступ.</p></abstract><trans-abstract xml:lang="en"><p>Persistent primary hyperparathyroidism (PHPT) following parathyroidectomy is most often caused by ectopia of a pathologically altered parathyroid gland (PTG). This condition makes accurate preoperative topographic diagnosis critically important, especially in repeat interventions, which themselves are associated with an increased risk of complications due to scar tissue formation and difficulties in anatomical identification. In the presented clinical case, a 70-year-old patient had persistent biochemical signs of PHPT after the initial surgery. During that intervention, a lesion identified on imaging as a PTG adenoma was removed, but postoperative histology unexpectedly revealed papillary thyroid cancer. This diagnostic dilemma clearly illustrates the morphological similarity of various neck lesions during intraoperative examination and underscores the value of intraoperative histological examination in ambiguous situations. To identify the cause of disease persistence, a comprehensive examination was performed. Repeat scintigraphy with SPECT/CT and multispiral computed tomography (MSCT) allowed for precise localization of the pathological focus. An ectopic adenoma of the right inferior PTG with aberrant migration, corresponding to Type C according to the Perrier classification, was diagnosed and subsequently successfully removed. This case confirms the necessity of a multidisciplinary approach and high oncological vigilance in managing patients with PHPT. It also demonstrates the practical utility of PTG ectopia classifications, which not only systematize anatomical location but also help the surgeon predict the technical complexity of the upcoming intervention, potential risks, and choose the optimal surgical approach.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>первичный гиперпаратиреоз</kwd><kwd>персистирующий гиперпаратиреоз</kwd><kwd>эктопия околощитовидной железы</kwd><kwd>паратиреоидный гормон</kwd><kwd>топическая диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>primary hyperparathyroidism</kwd><kwd>persistent hyperparathyroidism</kwd><kwd>parathyroid gland ectopia</kwd><kwd>parathyroid hormone</kwd><kwd>topographic diagnosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Топольницкий ЕБ, Милованова ТА, Апальков ДГ, Бибик ЕЕ, Гончарова АИ, Цветухин МО. 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