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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2026-163</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-10184</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОМОРБИДНЫЙ ПАЦИЕНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COMORBID PATIENT</subject></subj-group></article-categories><title-group><article-title>Взаимовлияние хронической сердечной недостаточности и хронической болезни почек в постинфарктном периоде: результаты годового исследования</article-title><trans-title-group xml:lang="en"><trans-title>The interplay between chronic heart failure and chronic kidney disease in the post-infarction period: One-year study results</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4875-1244</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елфимов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Elfimov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елфимов Дмитрий Анатольевич, к.м.н., доцент, доцент кафедры факультетской терапии </p><p>625023, Тюмень, ул. Одесская, д. 54</p></bio><bio xml:lang="en"><p>Dmitry A. Elfimov, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department of Faculty Therapy </p><p>54, Odesskaya St., Tyumen, 625023</p></bio><email xlink:type="simple">yelfimovda@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4724-0664</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елфимова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Elfimova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елфимова Ирина Валерьевна, к.м.н., доцент, доцент кафедры факультетской терапии </p><p>625023, Тюмень, ул. Одесская, д. 54</p></bio><bio xml:lang="en"><p>Irina V. Elfimova, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department of Faculty Therapy </p><p>54, Odesskaya St., Tyumen, 625023</p></bio><email xlink:type="simple">iyelfimova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-0472-5310</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чупраков</surname><given-names>A. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuprakov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чупраков Александр Евгеньевич, студент </p><p>625023, Тюмень, ул. Одесская, д. 54</p></bio><bio xml:lang="en"><p>Aleksandr E. Chuprakov, Student </p><p>54, Odesskaya St., Tyumen, 625023</p></bio><email xlink:type="simple">sasha13.02.2002@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тюменский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>26</day><month>06</month><year>2026</year></pub-date><volume>0</volume><issue>7</issue><fpage>220</fpage><lpage>227</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Елфимов Д.А., Елфимова И.В., Чупраков A.Е., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Елфимов Д.А., Елфимова И.В., Чупраков A.Е.</copyright-holder><copyright-holder xml:lang="en">Elfimov D.A., Elfimova I.V., Chuprakov A.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/10184">https://www.med-sovet.pro/jour/article/view/10184</self-uri><abstract><sec><title>Введение</title><p>Введение. Хроническая болезнь почек (ХБП) и острый инфаркт миокарда (ОИМ) образуют коморбидную пару, взаимно отягощающую течение и прогноз каждого из заболеваний. Пациенты с ХБП имеют значительно повышенный риск сердечно-сосудистых событий, в то время как перенесенный ОИМ усугубляет почечную дисфункцию.</p></sec><sec><title>Цель</title><p>Цель. Оценить взаимосвязь между тяжестью кардиальных повреждений и прогрессированием хронической болезни почек в постинфарктном периоде.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен анализ данных 100 пациентов после перенесенного ОИМ с годичным наблюдением. Критериями включения явились: возраст от 18 до 89 лет, подтвержденный диагноз ОИМ. У всех пациентов регистрировали кардиологические показатели и нефрологические параметры. Для статистического анализа использовали методы корреляционного анализа.</p></sec><sec><title>Результаты</title><p>Результаты. Хроническая болезнь почек была диагностирована у 61% обследованных. Выявлена выраженная взаимосвязь между тяжестью ХБП и суммарным индексом кардиальных событий (число перенесенных инфарктов миокарда и процедур чрескожных коронарных вмешательств (ЧКВ)). Каждая процедура ЧКВ была связана с увеличением вероятности развития ХБП стадий C3a-C4 на 42,6%, а каждый перенесенный инфаркт миокарда – на 38,2%. Отмечена тесная взаимосвязь между количеством ЧКВ и стадией хронической сердечной недостаточности, а также обратная зависимость с фракцией выброса левого желудочка. В течение годового периода наблюдения зарегистрировано существенное повышение уровня креатинина и микроальбуминурии.</p></sec><sec><title>Выводы</title><p>Выводы. Настоящее исследование, посвященное изучению взаимосвязи между хронической сердечной недостаточностью и хронической болезнью почек после инфаркта миокарда, продемонстрировало наличие выраженной связи между степенью поражения сердца и ухудшением функции почек. Было обнаружено, что суммарный индекс кардиальных событий обладает особенно тесной связью со стадией ХБП. Каждый эпизод коронарной патологии значимо увеличивал вероятность возникновения и развития ХБП, что отражалось в заметном увеличении концентрации креатинина и альбумина в моче на протяжении года наблюдения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Chronic kidney disease (CKD) and acute myocardial infarction (AMI) form a comorbid pair that mutually aggravates the course and prognosis of each condition. Patients with CKD have a significantly increased risk of cardiovascular events, while AMI exacerbates renal dysfunction.</p></sec><sec><title>Aim</title><p>Aim. To assess the relationship between the severity of cardiac damage and the progression of chronic kidney disease in the post-infarction period.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We analyzed data from 100 post-MI patients with a one-year follow-up. Inclusion criteria were: age 18 to 89 years and a confirmed MI diagnosis. Cardiac and renal parameters were recorded for all patients. Statistical analysis was performed using correlation methods.</p></sec><sec><title>Results</title><p>Results. Chronic kidney disease was diagnosed in 61% of the patients. A significant correlation was found between CKD severity and the cumulative cardiac event score (number of myocardial infarctions and percutaneous coronary interventions (PCI)). Each PCI was associated with a 42.6% increased likelihood of developing CKD stages C3a-C4, and each myocardial infarction with a 38.2% increase. A strong positive correlation was observed between the number of PCIs and the stage of chronic heart failure, and an inverse correlation with left ventricular ejection fraction. During the one-year follow-up, a significant increase in serum creatinine and microalbuminuria levels was recorded.</p></sec><sec><title>Conclusions</title><p>Conclusions. This study on the relationship between chronic heart failure and CKD after myocardial infarction demonstrated a strong association between the degree of cardiac impairment and worsening kidney function. The cumulative cardiac event score showed a particularly strong correlation with CKD stage. Each episode of coronary pathology significantly increased the risk of CKD onset and progression, reflected in a marked increase in serum creatinine and urinary albumin (albuminuria) levels over the one-year observation period.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>кардиоренальный синдром</kwd><kwd>чрескожное коронарное вмешательство</kwd><kwd>микроальбуминурия</kwd><kwd>скорость клубочковой фильтрации</kwd><kwd>прогрессирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>cardio-renal syndrome</kwd><kwd>percutaneous coronary intervention</kwd><kwd>albuminuria</kwd><kwd>glomerular filtration rate</kwd><kwd>disease progression</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Андрусев АМ, Перегудова НГ, Шинкарев МБ, Томилина НА. 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