<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2013-5-31-37</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1039</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Лечение гастроэзофагеальной рефлюксной болезни: краткий обзор рекомендаций Американской гастроэнтерологической ассоциации (часть II)</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of gastroesophageal reflux disease: guidelines of american gastroenterologists. p. II</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пиманов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pimanov</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ВГМУ, Витебск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vitebsk State Medical University, Vitebsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2013</year></pub-date><volume>0</volume><issue>5</issue><fpage>31</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пиманов С.И., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Пиманов С.И.</copyright-holder><copyright-holder xml:lang="en">Pimanov S.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1039">https://www.med-sovet.pro/jour/article/view/1039</self-uri><abstract><p>Гастроэзофагеальная рефлюксная болезнь может сопутствовать астме, хроническому кашлю или ларингиту, не являясь их причиной, а также быть одним из факторов, способствующих возникновению и поддержанию этих заболеваний. Пробное лечение ингибиторами протонной помпы рекомендуется для лечения экстраэзофагеальных симптомов у пациентов, которые имеют типичную гастроэзофагеальную рефлюксную болезнь. Эффект лечения ингибиторами протонной помпы не снижается у пациентов, принимающих клопидогрел, в то же время у них не повышается риск сердечно-сосудистых осложнений.</p></abstract><trans-abstract xml:lang="en"><p>Gastroesophageal reflux disease may co-occur with asthma, chronic cough or laryngitis while not being their cause; it may also be a factor contributing to the emergence and maintenance of the diseases. Trial therapy with proton pump inhibitors is recommended for the treatment of extraesophageal symptoms in patients with typical gastroesophageal reflux disease. The effect of treatment with proton pump inhibitors is not reduced in patients taking  clopidogrel, while the risk of cardiovascular complications in such patients does not increase.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гастроэзофагеальная рефлюксная болезнь</kwd><kwd>пищевод</kwd><kwd>ингибиторы протонной помпы</kwd><kwd>пищевод Барретта</kwd><kwd>эрозивный эзофагит</kwd><kwd>gastroesophageal reflux disease</kwd><kwd>esophagus</kwd><kwd>proton pump inhibitors</kwd><kwd>Barrett's esophagus</kwd><kwd>erosive esophagitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Peery A.F., Dellon E.S., Lund J. еt al. Burden of Gastrointestinal Disease in the United States: 2012 Update // Gastroenterology. 2012. Vol. 143. No5. P. 1179-1187.</mixed-citation><mixed-citation xml:lang="en">Peery A.F., Dellon E.S., Lund J. еt al. Burden of Gastrointestinal Disease in the United States: 2012 Update // Gastroenterology. 2012. Vol. 143. No5. P. 1179-1187.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Katz P.O., Gerson L.B., Vela M.F. Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease // Am. J. Gastroenterol. 2013. Vol. 108. P. 308-328.</mixed-citation><mixed-citation xml:lang="en">Katz P.O., Gerson L.B., Vela M.F. Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease // Am. J. Gastroenterol. 2013. Vol. 108. P. 308-328.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Rubenstein J.H, Scheiman J.M., Sadeghi S. et al. Esophageal adenocarcinoma incidence in individuals with gastroesophageal reflux: synthesis and estimates from population studies // Am. J. Gastroenterol. 2011. Vol. 106. P. 254-260.</mixed-citation><mixed-citation xml:lang="en">Rubenstein J.H, Scheiman J.M., Sadeghi S. et al. Esophageal adenocarcinoma incidence in individuals with gastroesophageal reflux: synthesis and estimates from population studies // Am. J. Gastroenterol. 2011. Vol. 106. P. 254-260.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Кайбышева В.О., Трухманов А.С., Ивашкин В.Т. Гастроэзофагеальная рефлюксная болезнь, резистентная к терапии ингибиторами протонной помпы // Росс. журн. гастроэнтерол., гепатологии, колопроктологии. 2011. №4. C. 4-13.</mixed-citation><mixed-citation xml:lang="en">Кайбышева В.О., Трухманов А.С., Ивашкин В.Т. Гастроэзофагеальная рефлюксная болезнь, резистентная к терапии ингибиторами протонной помпы // Росс. журн. гастроэнтерол., гепатологии, колопроктологии. 2011. №4. C. 4-13.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Solaymany-Dodaran M., Card T.R., West О. Cause-Specific Mortality of People With Barrett's Esophagus Compared With the General Population: A Population-Based Cohort Study // Gastroenterology. 2013. Vol. 144. No7. P. 1357-1383.</mixed-citation><mixed-citation xml:lang="en">Solaymany-Dodaran M., Card T.R., West О. Cause-Specific Mortality of People With Barrett's Esophagus Compared With the General Population: A Population-Based Cohort Study // Gastroenterology. 2013. Vol. 144. No7. P. 1357-1383.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Vakil N., van Zanten S.V., Kahrilas P. et al. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterol. 2006. Vol. 101. P. 1900-1920.</mixed-citation><mixed-citation xml:lang="en">Vakil N., van Zanten S.V., Kahrilas P. et al. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterol. 2006. Vol. 101. P. 1900-1920.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hunt R.H., Tytgat G.N., Malfertheiner P. et al. Whistler Consensus // J. Clin. Gastroenterol. 2007. Vol. 41. P. 47-50.</mixed-citation><mixed-citation xml:lang="en">Hunt R.H., Tytgat G.N., Malfertheiner P. et al. Whistler Consensus // J. Clin. Gastroenterol. 2007. Vol. 41. P. 47-50.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Tytgat G.N., McColl K., Tack J. et al. New algorithm for the treatment of gastro-oesophageal reflux disease // Aliment. Pharmacol. Ther. 2008. Vol. 27. P. 249-256.</mixed-citation><mixed-citation xml:lang="en">Tytgat G.N., McColl K., Tack J. et al. New algorithm for the treatment of gastro-oesophageal reflux disease // Aliment. Pharmacol. Ther. 2008. Vol. 27. P. 249-256.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Guyatt G.H., Oxman A.D., Vist G.E. et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations // BMJ. 2008. Vol. 336. P. 924-926.</mixed-citation><mixed-citation xml:lang="en">Guyatt G.H., Oxman A.D., Vist G.E. et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations // BMJ. 2008. Vol. 336. P. 924-926.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Malfertheiner P., Megraud F., O'Morain C. et al. Management of Helicobacter pylori infection - the Maastricht IV/Florence Consensus Report // Gut. 2012. Vol. 61. P. 646-664.</mixed-citation><mixed-citation xml:lang="en">Malfertheiner P., Megraud F., O'Morain C. et al. Management of Helicobacter pylori infection - the Maastricht IV/Florence Consensus Report // Gut. 2012. Vol. 61. P. 646-664.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kaltenbach T, Crockett S., Gerson L.B. Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach // Arch. Intern. Med. 2006 Vol. 166. P. 965-971.</mixed-citation><mixed-citation xml:lang="en">Kaltenbach T, Crockett S., Gerson L.B. Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach // Arch. Intern. Med. 2006 Vol. 166. P. 965-971.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Wileman S.M., McCann S., Grant A.M. et al. Medical versus surgical management for gastro-oesophageal reflux disease (GORD) in adults // Cochrane Database Syst. Rev. 2010. CD003243.</mixed-citation><mixed-citation xml:lang="en">Wileman S.M., McCann S., Grant A.M. et al. Medical versus surgical management for gastro-oesophageal reflux disease (GORD) in adults // Cochrane Database Syst. Rev. 2010. CD003243.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Johnstone J., Nerenberg K., Loeb M. Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneumonia // Aliment. Pharmacol. Ther. 2010. Vol. 31. P. 1165-1177.</mixed-citation><mixed-citation xml:lang="en">Johnstone J., Nerenberg K., Loeb M. Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneumonia // Aliment. Pharmacol. Ther. 2010. Vol. 31. P. 1165-1177.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Bhatt D.L., Scheiman J., Abraham N.S. et al. ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents // Circulation. 2008. Vol. 118. P. 1894-1909.</mixed-citation><mixed-citation xml:lang="en">Bhatt D.L., Scheiman J., Abraham N.S. et al. ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents // Circulation. 2008. Vol. 118. P. 1894-1909.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gerson L.B., McMahon D., Olkin I. et al. Lack of signifi cant interactions between clopidogrel and proton pump inhibitor therapy: meta-analysis of existing literature // Dig. Dis. Sci. 2012. Vol. 57. P. 1304-1313.</mixed-citation><mixed-citation xml:lang="en">Gerson L.B., McMahon D., Olkin I. et al. Lack of signifi cant interactions between clopidogrel and proton pump inhibitor therapy: meta-analysis of existing literature // Dig. Dis. Sci. 2012. Vol. 57. P. 1304-1313.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kwok C.S., Jeevanantham V., Dawn B. et al. No consistent evidence of differential cardiovascular risk amongst proton-pump inhibitors when used with clopidogrel: meta-analysis // Int. J. Cardiol. 2013 (in press).</mixed-citation><mixed-citation xml:lang="en">Kwok C.S., Jeevanantham V., Dawn B. et al. No consistent evidence of differential cardiovascular risk amongst proton-pump inhibitors when used with clopidogrel: meta-analysis // Int. J. Cardiol. 2013 (in press).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Chen M., Wei J.F., Xu Y.N. et al. A meta-analysis of impact of proton pump inhibitors on antiplatelet effect of clopidogrel // Cardiovasc. Ther. 2012. Vol. 30. P. 227-233.</mixed-citation><mixed-citation xml:lang="en">Chen M., Wei J.F., Xu Y.N. et al. A meta-analysis of impact of proton pump inhibitors on antiplatelet effect of clopidogrel // Cardiovasc. Ther. 2012. Vol. 30. P. 227-233.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Chen J., Chen S., Lian J. et al. Pharmacodynamic Impacts of Proton Pump Inhibitors on the Efficacy of Clopidogrel In Vivo - A Systematic Review // Clin. Cardiol. 2013. Vol. 36. No4. P. 184-189.</mixed-citation><mixed-citation xml:lang="en">Chen J., Chen S., Lian J. et al. Pharmacodynamic Impacts of Proton Pump Inhibitors on the Efficacy of Clopidogrel In Vivo - A Systematic Review // Clin. Cardiol. 2013. Vol. 36. No4. P. 184-189.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Кобалава ЖД, Шаварова Е.К. Резистентная артериальная гипертония: новое и неизменно значимое // Сердце. 2013. Т. 12. №2. С. 123-132.</mixed-citation><mixed-citation xml:lang="en">Кобалава ЖД, Шаварова Е.К. Резистентная артериальная гипертония: новое и неизменно значимое // Сердце. 2013. Т. 12. №2. С. 123-132.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
