medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2013-10-38-41medsovet-1121Research ArticleГепатологияHepatologyАлкогольная болезнь печени и алкоголизм – две болезни и одна проблемаAlcoholic liver disease and alcoholism: two diseases, one problemCамсоновА. А.SamsonovA. A.noemail@neicon.ruПлотниковаЕ. Ю.PlotnikovaE. Y.noemail@neicon.ruНикушкинаИ. Н.NikushkinaI. N.noemail@neicon.ruТалицкаяЕ. А.TalitskayaE. A.noemail@neicon.ruКрасноваМ. В.KrasnovaM. V.noemail@neicon.ruКрасновО. А.KrasnovO. A.noemail@neicon.ruМГМСУ им. А.И. ЕвдокимоваРоссияMSUMD named after A.I. Evdokimov, Russian Ministry of HealthRussian FederationГБОУ ВПО «КемГМА» Минздрава России, КемеровоРоссияSubepartment of primary care training, course director for clinical gastroenterology Kemerovo State Medical Academy, Russian Ministry of Health, KemerovoRussian FederationMSUMD named after A.I. Evdokimov, Russian Ministry of HealthRussian FederationМБЛПУ «Городская клиническая больница №1», НовокузнецкРоссияGastroenterology unit at City Clinical Hospital No. 1, NovokuznetskRussian FederationМБУЗ «ГКБ №3 им. М.А. Подгорбунского», КемеровоРоссияGastroenterology unit at Kuzbass Regional Centre for Hepatology, Clinical Hospital No. 3 named after M.A. Podgorbunskiy, KemerovoRussian FederationГБОУ ВПО «КемГМА» Минздрава России; МБУЗ «ГКБ №3 им. М.А. Подгорбунского», КемеровоРоссияSubdepartment of hospital surgery of Kemerovo State Medical Academy, Russian Ministry of Health, chief doctor at Clinical Hospital No. 3 named after M.A. Podgorbunskiy, KemerovoRussian Federation2013301220130103841Copyright © Cамсонов А.А., Плотникова Е.Ю., Никушкина И.Н., Талицкая Е.А., Краснова М.В., Краснов О.А., 20132013Cамсонов А.А., Плотникова Е.Ю., Никушкина И.Н., Талицкая Е.А., Краснова М.В., Краснов О.А.Samsonov A.A., Plotnikova E.Y., Nikushkina I.N., Talitskaya E.A., Krasnova M.V., Krasnov O.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/1121

Данная работа посвящена алкогольному поражению печени, которое развивается по типу стеатоза/стеатогепатита/фиброза с последующей трансформацией в цирроз печени. Описаны патогенетические механизмы алкогольного повреждения печени по типу стеатоза/стеатогепатита. В разделе лечения алкогольного стеатогепатита рассмотрены современные данные о применении препаратов с высоким уровнем доказательности и рекомендаций. Также в статье приводятся собственные исследования по качеству жизни и влиянию соматических жалоб у пациентов с разными вариантами жировой болезни печени.

The article highlights alcoholic liver disease manifested in steatosis/steatohepatitis/fibrosis, which further transforms into cirrhosis of the liver. The pathogenetic mechanisms of alcohol-induced lesions of the liver leading to steatosis/steatohepatitis are described. Section on the treatment of alcoholic steatohepatitis provides a review of current data on the use of drugs supported by strong evidence and recommendations. The authors also share results of their own research on quality of life and impact of somatic complaints in patients with different types of fatty liver disease.

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The authors declare that there are no conflicts of interest present.