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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2013-11-34-37</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1143</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Бронхиальная астма</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Bronchial asthma</subject></subj-group></article-categories><title-group><article-title>Мелкие воздухоносные пути при бронхиальной астме – возможности терапии</article-title><trans-title-group xml:lang="en"><trans-title>Small airways in asthma: treatment options</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зыков</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zykov</surname><given-names>K. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МГМСУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MSUMS</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2013</year></pub-date><volume>0</volume><issue>11</issue><fpage>34</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зыков К.А., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Зыков К.А.</copyright-holder><copyright-holder xml:lang="en">Zykov K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1143">https://www.med-sovet.pro/jour/article/view/1143</self-uri><abstract><p>Согласно современным представлениям, бронхиальная астма (БА) определяется как хроническое воспалительное заболевание воздухоносных путей, в котором играют роль многие клетки и клеточные элементы. Хроническое воспаление ассоциировано с гиперреактивностью воздухоносных путей, что ведет к повторяющимся эпизодам хрипов, одышки, стеснения в груди, кашля (особенно по ночам и ранним утром). Эти эпизоды обычно ассоциированы с распространенной, но вариабельной обструкцией воздухоносных путей, которая часто обратима спонтанно или под влиянием терапии [<xref ref-type="bibr" rid="cit1">1</xref>].</p></abstract><trans-abstract xml:lang="en"><p>According to the modern idea, bronchial asthma (BA) is a chronic inflammatory disease of the airways in which many cells and cellular elements play a role. Chronic inflammation is associated with airway hyperresponsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, (especially at night or in the early morning). These episodes are usually associated with widespread, but variable, airflow obstruction within the lung that is often reversible either spontaneously or with treatment [<xref ref-type="bibr" rid="cit1">1</xref>].</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бронхиальная астма</kwd><kwd>мелкие воздухоносные пути</kwd><kwd>ультрамелкодисперсный аэрозоль</kwd><kwd>hma</kwd><kwd>small airways</kwd><kwd>ultra-fine aerosol</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention (updated 2013). www.ginasthma.com</mixed-citation><mixed-citation xml:lang="en">Global Initiative for Asthma (GINA). 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