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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2016-6-12-17</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1274</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RHINOLOGY</subject></subj-group></article-categories><title-group><article-title>Возможности антибактериальной терапии затянувшихся и рецидивирующих форм риногенного синусита, а также синусита с наличием коморбидного фона</article-title><trans-title-group xml:lang="en"><trans-title>Prospects for antibacterial therapy of prolonged and recurrent rhinogenous sinusitis, and sinusitis with comorbidities</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крюков</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kryukov</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кунельская</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kunelskaya</surname><given-names>N. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуров</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gurov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Изотова</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Izotova</surname><given-names>G. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юшкина</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yushkina</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselyova</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский клинический институт оториноларингологии им. Л.И. Свержевского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research and Clinical Otorhinolaryngology Institute named after L.I. Sverzhevskiy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>6</issue><fpage>12</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крюков А.И., Кунельская Н.Л., Гуров А.В., Изотова Г.Н., Юшкина М.А., Киселева О.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Крюков А.И., Кунельская Н.Л., Гуров А.В., Изотова Г.Н., Юшкина М.А., Киселева О.А.</copyright-holder><copyright-holder xml:lang="en">Kryukov A.I., Kunelskaya N.L., Gurov A.V., Izotova G.N., Yushkina M.A., Kiselyova O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1274">https://www.med-sovet.pro/jour/article/view/1274</self-uri><abstract><p>Проблема острого синусита (ОС) продолжает оставаться актуальной в условиях современного здравоохранения, что объясняется целым рядом причин. Прежде всего, за последние годы не только не отмечено снижения заболеваемости ОС, но и наблюдается устойчивая тенденция к росту данной патологии как в России, так и во всем мире. К примеру, ежегодно в США синусит регистрируется у 16% взрослого населения [<xref ref-type="bibr" rid="cit1">1</xref>]. В России ОС ежегодно переносят 10 млн человек, хотя эту цифру можно считать заниженной, поскольку она учитывает только тяжелые манифестированные формы заболевания [<xref ref-type="bibr" rid="cit2">2</xref>]. Согласно последним статистическим данным Департамента здравоохранения г. Москвы, распространенность синуситов составляет 1 420 случаев на 100 тыс. взрослого населения [<xref ref-type="bibr" rid="cit3">3</xref>].</p></abstract><trans-abstract xml:lang="en"><p>The problem of acute sinusitis (AS) continues to be relevant in today's healthcare, what is explained by several reasons. First of all, it is not only that the incidence of AS did not decrease over the past years; moreover, it demonstrates sustainable growth both in Russia and wordlwide. For example, 16% of the US adult population present with sinusitis every year. [<xref ref-type="bibr" rid="cit1">1</xref>] In Russia, 10 million people suffer from AS every year, although the figure can be low since only severe manifestations of the disease are recorded. [<xref ref-type="bibr" rid="cit2">2</xref>] According to the latest statistics from the Department of Health of Moscow, the prevalence of sinusitis is 1420 cases per 100 thousand adults. 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