<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2016-6-22-25</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1276</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RHINOLOGY</subject></subj-group></article-categories><title-group><article-title>Риносинусит: классификация, эпидемиология, этиология и лечение</article-title><trans-title-group xml:lang="en"><trans-title>Rhinosinusitis: classification, epidemiology, etiology and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривопалов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivopalov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg Research Institute of Ear, Throat, Nose and Speech</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>6</issue><fpage>22</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кривопалов А.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Кривопалов А.А.</copyright-holder><copyright-holder xml:lang="en">Krivopalov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1276">https://www.med-sovet.pro/jour/article/view/1276</self-uri><abstract><p>Во всем мире регистрируется рост распространенности острых и хронических форм риносинуситов среди взрослого и детского населения. В статье отражены результаты современных исследований по распространенности риносинуситов, представлены классификации, этиологические аспекты, а также изложены основные тактические принципы ведения и антибактериальной терапии этого заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The incidence of acute and chronic rhinosinusitis among children and adult population is growing worldwide. The article tells about the results of recent research on the prevalence of rhinosinusitis, classification, etiological aspects, major therapeutic approaches and antibiotic treatments for the disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>риносинусит</kwd><kwd>антибактериальная терапия</kwd><kwd>Rhinosinusitis</kwd><kwd>antibiotic therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">HadLey J.A., Schaefer S.D. Clinical evaluation of rhinosinusitis: history and physical examination. Otolaryngology - Head Neck Surgery. 1997;117(3)pt 2:S8-S11. doi: 10.1016/S0194-5998(97)70002-0.</mixed-citation><mixed-citation xml:lang="en">HadLey J.A., Schaefer S.D. Clinical evaluation of rhinosinusitis: history and physical examination. Otolaryngology - Head Neck Surgery. 1997;117(3)pt 2:S8-S11. doi: 10.1016/S0194-5998(97)70002-0.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Lanza D., Kennedy D.W. Adult rhinosinusitis defined. Otolaryngology - Head Neck Surgery. 1997; 117(3)pt 2:S1-S7. doi:10.1016/s0194-5998(97)70001-9.</mixed-citation><mixed-citation xml:lang="en">Lanza D., Kennedy D.W. Adult rhinosinusitis defined. Otolaryngology - Head Neck Surgery. 1997; 117(3)pt 2:S1-S7. doi:10.1016/s0194-5998(97)70001-9.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Meltzer E.O., Hamilos D.L., Hadley J.A., Lanza D., Marple B., Nicklas R., Bachert C., Baraniuk J., Baroody F., Benninger M. Rhinosinusitis: establishing definitions for clinical research and patient care. Otolaryngology - Head Neck Surgery. 2004; 114(suppl.6):155-212. doi;10.1016/j.jaci.2004.09.029.</mixed-citation><mixed-citation xml:lang="en">Meltzer E.O., Hamilos D.L., Hadley J.A., Lanza D., Marple B., Nicklas R., Bachert C., Baraniuk J., Baroody F., Benninger M. Rhinosinusitis: establishing definitions for clinical research and patient care. Otolaryngology - Head Neck Surgery. 2004; 114(suppl.6):155-212. doi;10.1016/j.jaci.2004.09.029.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Meltzer E.O. Hamilos D.L. Rhinosinusitis diagnosis and management for the clinician: a synopsis of recent consensus guidelines. Mayo Clinic. Proceedings. 2011;86(5): 427-443. doi:10.4065/mcp.2010.0392.</mixed-citation><mixed-citation xml:lang="en">Meltzer E.O. Hamilos D.L. Rhinosinusitis diagnosis and management for the clinician: a synopsis of recent consensus guidelines. Mayo Clinic. Proceedings. 2011;86(5): 427-443. doi:10.4065/mcp.2010.0392.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Thomas M., Yawn B., Price D., Lund V., Mullol J., Fokkens W. EPOS Primary Care Guidelines: European Position Paper on the Primary Care Diagnosis and Management of Rhinosinusitis and Nasal Polyps 2007 - a summary. Primary Care Respiratory Journal. 2008; 17(2):79-89. doi:10.3132/pcrj.2008.00029.</mixed-citation><mixed-citation xml:lang="en">Thomas M., Yawn B., Price D., Lund V., Mullol J., Fokkens W. EPOS Primary Care Guidelines: European Position Paper on the Primary Care Diagnosis and Management of Rhinosinusitis and Nasal Polyps 2007 - a summary. Primary Care Respiratory Journal. 2008; 17(2):79-89. doi:10.3132/pcrj.2008.00029.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chow A., Benninger M., Brook I., Brozek J., Goldstein E., Hicks L., Pankey G., Seleznick M., Volturo G., Wald E., File T IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Clinical Infections Diseases. 2012; 54(suppl.8):e72-e112. doi:10.1093/cid/cir1043.</mixed-citation><mixed-citation xml:lang="en">Chow A., Benninger M., Brook I., Brozek J., Goldstein E., Hicks L., Pankey G., Seleznick M., Volturo G., Wald E., File T IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Clinical Infections Diseases. 2012; 54(suppl.8):e72-e112. doi:10.1093/cid/cir1043.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Fokkens WJ., Lund VJ., Mullol J. et al. EPOS 2012: European position paper on rhinosinusi-tis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology. 2012; 50(1):1-12. Доступно по: www.rhinologyjournal. com; www.ep3os.org.</mixed-citation><mixed-citation xml:lang="en">Fokkens WJ., Lund VJ., Mullol J. et al. EPOS 2012: European position paper on rhinosinusi-tis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology. 2012; 50(1):1-12. Доступно по: www.rhinologyjournal. com; www.ep3os.org.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Страчунский Л.С., Каманин Е.И., Тарасов А.А. Антибактериальная терапия синусита. Методические рекомендации для клиницистов. Клиническая микробиология и антимикробная химиотерапия. 1999;1(1):83-88.</mixed-citation><mixed-citation xml:lang="en">Страчунский Л.С., Каманин Е.И., Тарасов А.А. Антибактериальная терапия синусита. Методические рекомендации для клиницистов. Клиническая микробиология и антимикробная химиотерапия. 1999;1(1):83-88.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Свистушкин В.М., Гринев И.А., Стецюк О.У., Андреева И.В. Рекомендации по ведению взрослых пациентов с острым риносинуситом: достижим ли консенсус? Лечащий врач. 2012; 11:90-96.</mixed-citation><mixed-citation xml:lang="en">Свистушкин В.М., Гринев И.А., Стецюк О.У., Андреева И.В. Рекомендации по ведению взрослых пациентов с острым риносинуситом: достижим ли консенсус? Лечащий врач. 2012; 11:90-96.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Абдулкеримов Х.Т., Гаращенко Т.И., Кошель В.И., Рязанцев С.В., Свистушкин В.М. Принципы этиопатогенетической терапии острых синуситов. Под ред. С.В. Рязанцева СПб.: Полифорум Групп; 2013.</mixed-citation><mixed-citation xml:lang="en">Абдулкеримов Х.Т., Гаращенко Т.И., Кошель В.И., Рязанцев С.В., Свистушкин В.М. Принципы этиопатогенетической терапии острых синуситов. Под ред. С.В. Рязанцева СПб.: Полифорум Групп; 2013.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Пискунов С.З., Пискунов Г.З. Риносинусит М.: ООО Издательство «МИА»; 2013.</mixed-citation><mixed-citation xml:lang="en">Пискунов С.З., Пискунов Г.З. Риносинусит М.: ООО Издательство «МИА»; 2013.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Thaler E., Kennedy D. Rhinosinusitis. New York, NY: Springer; 2008.</mixed-citation><mixed-citation xml:lang="en">Thaler E., Kennedy D. Rhinosinusitis. New York, NY: Springer; 2008.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Hastan D., Fokkens W., Bachert C., Newson R., Bislimovska J., Bockelbrink A., Bousquet P., Brozek G., Bruno A., Dahlen S., Forsberg B., Gunnbjorns-dottir M., Kasper L., Kramer U., Kowalski M., Lange B., Lundback B., Salagean E., Todo-Bom A., Tomassen P., Toskala E., van Drunen C., Bousquet J., Zuberbier T., Jarvis D., Burney P. Chronic rhinosi-nusitis in Europe - an underestimated disease. A GA2LEN study. Allergy. 2011; 66(9)1216-1223. doi: 10.1111/j.1398-9995.2011.02646.x.</mixed-citation><mixed-citation xml:lang="en">Hastan D., Fokkens W., Bachert C., Newson R., Bislimovska J., Bockelbrink A., Bousquet P., Brozek G., Bruno A., Dahlen S., Forsberg B., Gunnbjorns-dottir M., Kasper L., Kramer U., Kowalski M., Lange B., Lundback B., Salagean E., Todo-Bom A., Tomassen P., Toskala E., van Drunen C., Bousquet J., Zuberbier T., Jarvis D., Burney P. Chronic rhinosi-nusitis in Europe - an underestimated disease. A GA2LEN study. Allergy. 2011; 66(9)1216-1223. doi: 10.1111/j.1398-9995.2011.02646.x.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Hoffmans R., Schermer T., Van Weel C., Fokkens W. Management of rhinosinusitis in Dutch general practice. Primary Care Respiratory Journal. 2011;20(1):64-70. doi: 10.4104/pcrj.2010.00064.</mixed-citation><mixed-citation xml:lang="en">Hoffmans R., Schermer T., Van Weel C., Fokkens W. Management of rhinosinusitis in Dutch general practice. Primary Care Respiratory Journal. 2011;20(1):64-70. doi: 10.4104/pcrj.2010.00064.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kaliner M.A., Osguthorpe J.D., Fireman P., Anon J., Georgitis J., Davis M., Naclerio M., Kennedy D. Sinusitis: bench to bedside. Current findings, future directions. Journal of Allergy Clinical. Immunology.1997; 99(6)(3):829-848. doi:10.1016/s0091-6749(97)70041-1.</mixed-citation><mixed-citation xml:lang="en">Kaliner M.A., Osguthorpe J.D., Fireman P., Anon J., Georgitis J., Davis M., Naclerio M., Kennedy D. Sinusitis: bench to bedside. Current findings, future directions. Journal of Allergy Clinical. Immunology.1997; 99(6)(3):829-848. doi:10.1016/s0091-6749(97)70041-1.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Osguthorpe J.D., Hadley J.A. Rhinosinusitisю. Medical Clinics of North America. 1999;83(1):27-42. doi:10.1016/s0025-7125(05)70085-7.</mixed-citation><mixed-citation xml:lang="en">Osguthorpe J.D., Hadley J.A. Rhinosinusitisю. Medical Clinics of North America. 1999;83(1):27-42. doi:10.1016/s0025-7125(05)70085-7.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Sande M.A., Gwaltney J.M. Acute community-acquired bacterial sinusitis: Continuing challenges and current management. Clinical Infections Diseases. 2004;39(suppl.3):151-158. doi:10.1086/421353.</mixed-citation><mixed-citation xml:lang="en">Sande M.A., Gwaltney J.M. Acute community-acquired bacterial sinusitis: Continuing challenges and current management. Clinical Infections Diseases. 2004;39(suppl.3):151-158. doi:10.1086/421353.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Chen Y., Dales R., Lin M. The epidemiology of chronic rhinosinusitis in Canadians. Laryngoscope. 2003;113(7): 1199-1205. doi:10.1097/00005537-200307000-00016.</mixed-citation><mixed-citation xml:lang="en">Chen Y., Dales R., Lin M. The epidemiology of chronic rhinosinusitis in Canadians. Laryngoscope. 2003;113(7): 1199-1205. doi:10.1097/00005537-200307000-00016.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">The Chief Public Health Officer's report on the state of public health in Canada 2013: Infectious diseases - The never-ending threat. Ottawa ON: Public Health Agency of Canada. 2013: Available at: http//www.phac-aspc.gc.ca/cph-orsphc-respcacsp/2013/assets/pdf/2013-eng.pdf</mixed-citation><mixed-citation xml:lang="en">The Chief Public Health Officer's report on the state of public health in Canada 2013: Infectious diseases - The never-ending threat. Ottawa ON: Public Health Agency of Canada. 2013: Available at: http//www.phac-aspc.gc.ca/cph-orsphc-respcacsp/2013/assets/pdf/2013-eng.pdf</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Halawi A.M., Smith S.S., Chandra R.K. Chronic rhinosinusitis: Epidemiology and cost. Allergy and Asthma Proceedinds. 2013;34(4): 328-334. doi:10.2500/aap.2013.34.3675.</mixed-citation><mixed-citation xml:lang="en">Halawi A.M., Smith S.S., Chandra R.K. Chronic rhinosinusitis: Epidemiology and cost. Allergy and Asthma Proceedinds. 2013;34(4): 328-334. doi:10.2500/aap.2013.34.3675.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Крюков А.И., Студеный М.Е., Артемьев М.Е., Чумаков П.Л., Рынков Д.Л., Горин Д.С. Лечение пациентов с риносинуситами: возможности консервативного и оперативного воздействия. Медицинский совет. 2012;11: 52-56.</mixed-citation><mixed-citation xml:lang="en">Крюков А.И., Студеный М.Е., Артемьев М.Е., Чумаков П.Л., Рынков Д.Л., Горин Д.С. Лечение пациентов с риносинуситами: возможности консервативного и оперативного воздействия. Медицинский совет. 2012;11: 52-56.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Радциг Е.Ю., Малыгина Л.В., Лапицкая А.С. Роль респираторных вирусов в этиологии риносинусита у детей. Вестник оториноларингологии. 2014;6:39-40. doi:10.17116/ otorino201439-40.</mixed-citation><mixed-citation xml:lang="en">Радциг Е.Ю., Малыгина Л.В., Лапицкая А.С. Роль респираторных вирусов в этиологии риносинусита у детей. Вестник оториноларингологии. 2014;6:39-40. doi:10.17116/ otorino201439-40.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Селькова Е.П., Радциг Е.Ю., Бугайчук О.В., Малыгина Л.В., Лапицкая А.С., Гудова Н.А., Гренкова Т.А. Респираторные вирусы в этиологии риносинусита и острого среднего гнойного отита у детей. Эпидемиология и Инфекционные Болезни. 2015;3: 21-23.</mixed-citation><mixed-citation xml:lang="en">Селькова Е.П., Радциг Е.Ю., Бугайчук О.В., Малыгина Л.В., Лапицкая А.С., Гудова Н.А., Гренкова Т.А. Респираторные вирусы в этиологии риносинусита и острого среднего гнойного отита у детей. Эпидемиология и Инфекционные Болезни. 2015;3: 21-23.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Никулин А.А., Козлов Р.С., Синопальников А.И. Новая лекарственная форма амоксициллина/ клавуланата. Фарматека, 2010;12: 53-60.</mixed-citation><mixed-citation xml:lang="en">Никулин А.А., Козлов Р.С., Синопальников А.И. Новая лекарственная форма амоксициллина/ клавуланата. Фарматека, 2010;12: 53-60.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Кривопалов А.А., Вахрушев С.Г. Система специализированной оториноларингологической помощи в Красноярском крае. Российская оториноларингология. 2013; 4: 50-54.</mixed-citation><mixed-citation xml:lang="en">Кривопалов А.А., Вахрушев С.Г. Система специализированной оториноларингологической помощи в Красноярском крае. Российская оториноларингология. 2013; 4: 50-54.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Strachunskiy L.S., Kamanin E.I., Tarasov A.A. Antimicrobial treatment of sinusitis. Guidelines for clinicians. Klinicheskaya Mikrobiologiya i Antimikrobnaya Terapiya. 1999;1(1):83-88.</mixed-citation><mixed-citation xml:lang="en">Strachunskiy L.S., Kamanin E.I., Tarasov A.A. Antimicrobial treatment of sinusitis. Guidelines for clinicians. Klinicheskaya Mikrobiologiya i Antimikrobnaya Terapiya. 1999;1(1):83-88.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Svistushkin V.M., Grinev I.A., Stetsyuk O.U., Andreeva I.V. Guidelines for the management of adult patients with acute rhinosinusitis: is a consensus possible ? Lechaschiy Vrach. 2012; 11:90-96.</mixed-citation><mixed-citation xml:lang="en">Svistushkin V.M., Grinev I.A., Stetsyuk O.U., Andreeva I.V. Guidelines for the management of adult patients with acute rhinosinusitis: is a consensus possible ? Lechaschiy Vrach. 2012; 11:90-96.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Abdulkerimov K.T, Garaschenko T.I., Koshel V.I., Ryazantsev S.V., Svistushkin V.M. The principles of etiopathogenetic treatment of acute sinusitis. Ed. by S.V. Ryazantsev SPb .: Poliform group, 2013.</mixed-citation><mixed-citation xml:lang="en">Abdulkerimov K.T, Garaschenko T.I., Koshel V.I., Ryazantsev S.V., Svistushkin V.M. The principles of etiopathogenetic treatment of acute sinusitis. Ed. by S.V. Ryazantsev SPb .: Poliform group, 2013.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Piskunov S.Z., Piskunov V.S. Rhinosinusitis M.: MIA publishing, 2013.</mixed-citation><mixed-citation xml:lang="en">Piskunov S.Z., Piskunov V.S. Rhinosinusitis M.: MIA publishing, 2013.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Kryukov A.I., Studeny M.E., Artemyev M.E., Chumakov P.L., Rynkov D.L., Gorin D.S. Treatment of patients with rhinosinusitis: prospects for conservative and surgical impact. Meditsinskiy Sovet. 2012;11: 52-56.</mixed-citation><mixed-citation xml:lang="en">Kryukov A.I., Studeny M.E., Artemyev M.E., Chumakov P.L., Rynkov D.L., Gorin D.S. Treatment of patients with rhinosinusitis: prospects for conservative and surgical impact. Meditsinskiy Sovet. 2012;11: 52-56.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Radtsig E.Y., Malygina L.V., Lapitskaya A.S. The role of respiratory viruses in the etiology of rhinosinusitis in children. Vestnik Otorinolaringologii. 2014;6:39-40. doi:10.17116/otorino201439-40.</mixed-citation><mixed-citation xml:lang="en">Radtsig E.Y., Malygina L.V., Lapitskaya A.S. The role of respiratory viruses in the etiology of rhinosinusitis in children. Vestnik Otorinolaringologii. 2014;6:39-40. doi:10.17116/otorino201439-40.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Selkova E.P., Radtsig E.Y., Bugaychuk O.V., Malygina L.V., Lapitskaya A.S., Gudova N.A., Grenkova T.A. Respiratory viruses in the etiology of acute rhinosinusitis and acute purulent otitis media in children. Epidemiologiya i Infektsionnye Bolezni. 2015;3: 21-23.</mixed-citation><mixed-citation xml:lang="en">Selkova E.P., Radtsig E.Y., Bugaychuk O.V., Malygina L.V., Lapitskaya A.S., Gudova N.A., Grenkova T.A. Respiratory viruses in the etiology of acute rhinosinusitis and acute purulent otitis media in children. Epidemiologiya i Infektsionnye Bolezni. 2015;3: 21-23.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Nikulin A.A., Kozlov R.S., Sinopalnikov A.I. A new formulation of amoxicillin/clavulanate. Pharmateka, 2010;12: 53-60.</mixed-citation><mixed-citation xml:lang="en">Nikulin A.A., Kozlov R.S., Sinopalnikov A.I. A new formulation of amoxicillin/clavulanate. Pharmateka, 2010;12: 53-60.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Krivopalov A.A., Vakhrushev S.G. Specialized ENT care in the Krasnoyarsk Territory. Rossiyskaya Otorinolaringologiya. 2013; 4: 50-54.</mixed-citation><mixed-citation xml:lang="en">Krivopalov A.A., Vakhrushev S.G. Specialized ENT care in the Krasnoyarsk Territory. Rossiyskaya Otorinolaringologiya. 2013; 4: 50-54.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
