<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2015-3-18-23</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-130</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RHINOLOGY</subject></subj-group></article-categories><title-group><article-title>Комплексная терапия хронического верхнечелюстного синусита</article-title><trans-title-group xml:lang="en"><trans-title>Combined treatment of acute maxillary sinusitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крюков</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kryukov</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туровский</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Turovskiy</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Царапкин</surname><given-names>Г. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsarapkin</surname><given-names>G. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Изотова</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Izotova</surname><given-names>G. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Товмасян</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tovmasyan</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоткина</surname><given-names>К. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedotkina</surname><given-names>K. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горин</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorin</surname><given-names>D. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский научно-практический центр оториноларингологии им. Л.И. Свержевского Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Otorhinolaryngology Research and Practical Centre named after L.I. Sverzhevskiy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2015</year></pub-date><volume>0</volume><issue>3</issue><fpage>18</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крюков А.И., Туровский А.Б., Царапкин Г.Ю., Изотова Г.Н., Товмасян А.С., Федоткина К.М., Горин Д.С., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Крюков А.И., Туровский А.Б., Царапкин Г.Ю., Изотова Г.Н., Товмасян А.С., Федоткина К.М., Горин Д.С.</copyright-holder><copyright-holder xml:lang="en">Kryukov A.I., Turovskiy A.B., Tsarapkin G.Y., Izotova G.N., Tovmasyan A.S., Fedotkina K.M., Gorin D.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/130">https://www.med-sovet.pro/jour/article/view/130</self-uri><abstract><p>Хронический риносинусит является актуальной проблемой современной медицины. За последние 20 лет заболеваемость им увеличилась в 2 раза. По данным литературы, она повышается с возрастом: от 20 до 29 лет она составляет 2,7%, от 50 до 59 лет - 6,6% [<xref ref-type="bibr" rid="cit1">1</xref>], что на фоне наблюдающегося старения населения придает проблеме воспалительных заболеваний околоносовых пазух (ОНП) еще большую значимость. Женщины страдают хроническим синуситом в 1,5 раза чаще, чем мужчины. Среди пациентов, находящихся на лечении в оториноларингологических стационарах, от 15 до 36% имеют заболевания околоносовых пазух носа (ОНп) [<xref ref-type="bibr" rid="cit2">2</xref>].</p></abstract><trans-abstract xml:lang="en"><p>Chronic rhinosinusitis is a relevant healthcare issue the incidence of which has increased twofold over the past 20 years. According to the literature, the incidence grows with age: in people aged 20 to 29 years, it equals 2.7%, and in people from 50 to 59 years - 6.6% [<xref ref-type="bibr" rid="cit1">1</xref>]. Against a background of population ageing, inflammatory diseases of the paranasal sinuses (PNS) are becoming a challenge. Women suffer from chronic sinusitis 1.5 times more often than men. 15 to 36% of in-patients at ENT units are people suffering from diseases of the paranasal sinuses (PNS) [<xref ref-type="bibr" rid="cit2">2</xref>].</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический синусит</kwd><kwd>респираторные фторхинолоны</kwd><kwd>интраназальные кортикостероиды</kwd><kwd>ИНГКС</kwd><kwd>chronic sinusitis</kwd><kwd>respiratory fluoroquinolones</kwd><kwd>intranasal corticosteroids (INCS)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bebear CM, Renaudin H, Boudjadja A, Bebear C. In vitro activity of BAY 12-8039, a new fLuoro-quinoLone against mycopLasmas. Antimicrob Agents Chemother, 1998, 42: 703-4.</mixed-citation><mixed-citation xml:lang="en">Bebear CM, Renaudin H, Boudjadja A, Bebear C. In vitro activity of BAY 12-8039, a new fLuoro-quinoLone against mycopLasmas. Antimicrob Agents Chemother, 1998, 42: 703-4.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">BLondeau J, Fass R. In vitro activity of BAY 12-8039, a new 8-methoxyquinoLone. Antimicrob Agents Chemother, 1997, 41: 1818-24.</mixed-citation><mixed-citation xml:lang="en">BLondeau J, Fass R. In vitro activity of BAY 12-8039, a new 8-methoxyquinoLone. Antimicrob Agents Chemother, 1997, 41: 1818-24.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">LosaetaL Е, Woodcock J, Andrews J, BosweLL F, BrenwaLd N, Wise R. In vitro activity of BAY 12-8039, a new fLuoroquinoLone. Antimicrob Agents Chemother, 1997, 41: 101-6.</mixed-citation><mixed-citation xml:lang="en">LosaetaL Е, Woodcock J, Andrews J, BosweLL F, BrenwaLd N, Wise R. In vitro activity of BAY 12-8039, a new fLuoroquinoLone. Antimicrob Agents Chemother, 1997, 41: 101-6.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Duffy L, Kempf M, Crabb D, WaLL W, Herrington J. In vitro activity of moxifLoxacin and six other new antimicrobiaLs against MycopLasma pneu-moniae. Proceedings of the 39th ICAACf; 1999: 252, Sep 26-29; San Francisco.</mixed-citation><mixed-citation xml:lang="en">Duffy L, Kempf M, Crabb D, WaLL W, Herrington J. In vitro activity of moxifLoxacin and six other new antimicrobiaLs against MycopLasma pneu-moniae. Proceedings of the 39th ICAACf; 1999: 252, Sep 26-29; San Francisco.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">ULLmann U, Schubert S, Krausse R. Comparative in-vitro activity of LevofLoxacin, other fLuoroquinoLones, doxycycLine and erythromycin against UreapLasma ureaLyticum and MycopLasma hominis. J Antimicrob Chemother 1999, 43(C): 33-6.</mixed-citation><mixed-citation xml:lang="en">ULLmann U, Schubert S, Krausse R. Comparative in-vitro activity of LevofLoxacin, other fLuoroquinoLones, doxycycLine and erythromycin against UreapLasma ureaLyticum and MycopLasma hominis. J Antimicrob Chemother 1999, 43(C): 33-6.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gomez-Lus R, Adrian F, deL Campo R, et. aL. Comparative in vitro bacteriostatic and bactericidaL activity of trovafLoxacin, LevofLoxacin and moxifLoxacin against cLinicaL and environmentaL isoLates of LegioneLLa spp. Int J Antimicrob Agents, 2001, 18: 49-54.</mixed-citation><mixed-citation xml:lang="en">Gomez-Lus R, Adrian F, deL Campo R, et. aL. Comparative in vitro bacteriostatic and bactericidaL activity of trovafLoxacin, LevofLoxacin and moxifLoxacin against cLinicaL and environmentaL isoLates of LegioneLLa spp. Int J Antimicrob Agents, 2001, 18: 49-54.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen R. The antibiotic treatment of acute oti-tis media and sinusitis in chiLdren. Diagn MicrobioL Infect Dis, 1997, 27: 49-53.</mixed-citation><mixed-citation xml:lang="en">Cohen R. The antibiotic treatment of acute oti-tis media and sinusitis in chiLdren. Diagn MicrobioL Infect Dis, 1997, 27: 49-53.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">GwaLtney JM. Acute community-acquired sinusitis. CLin. Infect. Dis. 1996, 23: 12091223.</mixed-citation><mixed-citation xml:lang="en">GwaLtney JM. Acute community-acquired sinusitis. CLin. Infect. Dis. 1996, 23: 12091223.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">HampeL B. CLinicaL needs in the miLLennium -rhinosinusitis - the roLe of moxifLoxacin. - 1st Intern. MoxifLoxacin Symp., BerLin,1999, Ed. MandeLL L. Springer-VerLag, 2000: 174-177.</mixed-citation><mixed-citation xml:lang="en">HampeL B. CLinicaL needs in the miLLennium -rhinosinusitis - the roLe of moxifLoxacin. - 1st Intern. MoxifLoxacin Symp., BerLin,1999, Ed. MandeLL L. Springer-VerLag, 2000: 174-177.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">KLossek JM, Arvis P and study group. MoxifLoxacin versus trovafLoxacin in the treatment of acute bacteriaL maxiLLary sinusitis: a muLtinationaL, doubLe-bLind, randomised study. - 3rd Eur. Congr. Chemother., Madrid, 2000, Poster.</mixed-citation><mixed-citation xml:lang="en">KLossek JM, Arvis P and study group. MoxifLoxacin versus trovafLoxacin in the treatment of acute bacteriaL maxiLLary sinusitis: a muLtinationaL, doubLe-bLind, randomised study. - 3rd Eur. Congr. Chemother., Madrid, 2000, Poster.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Stierna P. In: Kennedy DW, BoLger WE, Zinreich SJ, eds. Diseases of the sinuses: diagnosis and management. HamiLton, Ontario: B.C. Decker. 2001: 35-46.</mixed-citation><mixed-citation xml:lang="en">Stierna P. In: Kennedy DW, BoLger WE, Zinreich SJ, eds. Diseases of the sinuses: diagnosis and management. HamiLton, Ontario: B.C. Decker. 2001: 35-46.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Brannan MD, SeiberLing V, CutLer DL et aL. Lack of systemic activity with intranasaL mometa-sone furoate. Ann ALLergy Asthma ImmunoL, 1997, 97: 198.</mixed-citation><mixed-citation xml:lang="en">Brannan MD, SeiberLing V, CutLer DL et aL. Lack of systemic activity with intranasaL mometa-sone furoate. Ann ALLergy Asthma ImmunoL, 1997, 97: 198.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Lund VJ, Kennedy DW. Ann OtoL RhinoL LaringoL, 1995, 167(h): 17-21.</mixed-citation><mixed-citation xml:lang="en">Lund VJ, Kennedy DW. Ann OtoL RhinoL LaringoL, 1995, 167(h): 17-21.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
