medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2016-10-74-83medsovet-1408Research ArticleОнкологияOncologyПероральные формы цитостатиков в лечении метастатического рака молочной железы. Роль в клинической практикеPERORAL FORMS OF CYTOSTATIC DRUGS IN THERAPY OF METASTATIC MAMMARY GLAND CANCER: ROLE IN CLINICAL PRACTICEТЕЛЕТАЕВАГ. М.TELETAEVAG. M.

к.м.н.

Санкт-Петербург

PhD in medicine

СЕМИГЛАЗОВАТ. Ю.SEMIGLAZOVAT. Y.

д.м.н.

Санкт-Петербург

MD

ЖАБИНАА. С.ZHABINAА. S.

к.м.н.

Санкт-Петербург

ЛАТИПОВАД. Х.LATIPOVAD. H.

к.м.н.

Санкт-Петербург

PhD in medicine

КЛИМЕНКОВ. В.KLIMENKOV. V.

к.м.н.

Санкт-Петербург

PhD in medicine

КОТОВАЗ. С.KOTOVAZ. S.

Санкт-Петербург

СЕМЕНОВАА. И.SEMENOVAA. I.

к.м.н.

Санкт-Петербург

PhD in medicine

ПРОЦЕНКОС. А.PROTSENKOS. A.

д.м.н.

Санкт-Петербург

MD

СЕМИГЛАЗОВВ. В.SEMIGLAZOVV. V.

д.м.н., профессор

Санкт-Петербург

MD, Prof.

Научно-исследовательский институт онкологии им. Н.Н. ПетроваРоссияFSBI Petrov Scientific and Research Institute of Oncology of the Ministry of Health of RussiaRussian FederationНаучно-исследовательский институт онкологии им. Н.Н. Петрова; Северо-Западный государственный медицинский университет им. И.И. МечниковаРоссияFSBI Petrov Scientific and Research Institute of Oncology of the Ministry of Health of Russia; State Budgetary Educational Institution of Higher Professional Education Mechnikov North-Western State Medical University of the Ministry of Health of RussiaRussian FederationНаучно-исследовательский институт онкологии им. Н.Н. Петрова; Санкт-Петербургский клинический научно-практический центр специализированных видов медицинской помощи (онкологический)РоссияFSBI Petrov Scientific and Research Institute of Oncology of the Ministry of Health of Russia; State Budgetary Healthcare Establishment Saint-Petersburg Clinical Scientific and Practical Center of Specialized Medical Aid Types (Oncologic)Russian FederationНаучно-исследовательский институт онкологии им. Н.Н. Петрова; Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. ПавловаРоссияFSBI Petrov Scientific and Research Institute of Oncology of the Ministry of Health of Russia; State Budgetary Educational Institution of Higher Professional Education Pavlov Saint-Petersburg State Medical University of the Ministry of Health of RussiaRussian Federation2016301220160107483Copyright © ТЕЛЕТАЕВА Г.М., СЕМИГЛАЗОВА Т.Ю., ЖАБИНА А.С., ЛАТИПОВА Д.Х., КЛИМЕНКО В.В., КОТОВА З.С., СЕМЕНОВА А.И., ПРОЦЕНКО С.А., СЕМИГЛАЗОВ В.В., 20162016ТЕЛЕТАЕВА Г.М., СЕМИГЛАЗОВА Т.Ю., ЖАБИНА А.С., ЛАТИПОВА Д.Х., КЛИМЕНКО В.В., КОТОВА З.С., СЕМЕНОВА А.И., ПРОЦЕНКО С.А., СЕМИГЛАЗОВ В.В.TELETAEVA G.M., SEMIGLAZOVA T.Y., ZHABINA А.S., LATIPOVA D.H., KLIMENKO V.V., KOTOVA Z.S., SEMENOVA A.I., PROTSENKO S.A., SEMIGLAZOV V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/1408

Современные лечебные подходы позволяют достичь стойкого терапевтического эффекта, продления и максимально длительного сохранения качества жизни больных метастатическим раком молочной железы. Оптимальной последовательности применения цитостатических агентов в настоящее время не существует. Преимущество использования пероральных форм цитостатиков связано с легкостью их применения в клинической практике, отсутствием необходимости венопункции и уменьшением потребности в госпитализации, а также с возможностью более комфортного лечения в домашних условиях. Благодаря активному использованию пероральных форм винорелбина, фторпиримидинов, метотрексата, циклофосфамида, этопозида, у пациентов появилась возможность выбора: находиться в стационаре или лечиться амбулаторно в домашних условиях с минимальными изменениями образа жизни.

Modern therapeutic approaches allow achieving stable therapeutic effect, extension and maximum long-term preservation of the quality of life of metastatic mammary gland cancer patients. Currently there is no optimal consequence of cytostatic agents use. The advantage of using cytostatic peroral forms is related to easiness of their use in clinical practice, no necessity in venopuncture and reduction of need in hospitalization, as well as with the possibility of a more convenient therapy domiciliary. Due to active use of peroral forms of vinorelbine, fluoropyrimidines, methotrexate, cyclophosphamide, ethopozide, patients received a possibility to choose: to remain in the inpatient hospital or to undergo outpatient therapy domiciliary with minimum changes of the style of life.

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The authors declare that there are no conflicts of interest present.