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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2016-18-18-22</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1479</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНФЕКЦИИ В ОТОРИНОЛАРИНГОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INFECTIONS IN OTORHINOLARYNGOLOGY</subject></subj-group></article-categories><title-group><article-title>Особенности антибактериальной терапии гнойно-воспалительной патологии лор-органов</article-title><trans-title-group xml:lang="en"><trans-title>Peculiarities of antibacterial therapy of purulent and inflammatory pathology of ent-organs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крюков</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kryukov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуров</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gurov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юшкина</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yushkina</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Изотова</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Izotova</surname><given-names>G. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.б.н.</p></bio><bio xml:lang="en"><p>PhD in biology</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколов</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolov</surname><given-names>S. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский клинический институт оториноларингологии им. Л.И. Свержевского Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Healthcare Establishment Sverzhevsky Scientific and Research Institute of Otolaryngology of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>18</issue><fpage>18</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крюков А.И., Гуров А.В., Юшкина М.А., Изотова Г.Н., Соколов С.С., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Крюков А.И., Гуров А.В., Юшкина М.А., Изотова Г.Н., Соколов С.С.</copyright-holder><copyright-holder xml:lang="en">Kryukov A.I., Gurov A.V., Yushkina M.A., Izotova G.N., Sokolov S.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1479">https://www.med-sovet.pro/jour/article/view/1479</self-uri><abstract><p>Статья посвящена проблемам диагностики и лечения гнойно-воспалительной патологии ЛОР-органов. Авторы рассматривают основные причины острой очаговой инфекции ЛОР-органов, а также факторы, способствующие хронизации воспаления. В статье представлены данные о наиболее распространенных возбудителях гнойно-воспалительных заболеваний ЛОР-органов, особенностях микробных биоценозов ЛОР-органов в норме и при сопутствующих заболеваниях, освещаются вопросы рациональной антибактериальной терапии с использованием коротких высокодозных курсов антимикробных препаратов. </p></abstract><trans-abstract xml:lang="en"><p>The article deals with problems of diagnostics and therapy of purulent and inflammatory pathology of ENT-organs. The authors consider major reasons of acute focal infection of ENT-organs as well as factors contributing to inflammation chronization. The article provides data on the most popular causative agents of purulent and inflammatory ENT-organs diseases, peculiarities of microbe biocenoses of ENT-organs in normal conditions and in case of concomitant diseases, issues of rational antibacterial therapy are considered with use of short high-dosage courses of antimicrobial drugs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гнойно-воспалительные заболевания ЛОР-органов</kwd><kwd>антибактериальная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>purulent and inflammatory diseases of ENT-organs</kwd><kwd>antibacterial therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Руководство по очаговой инфекции в оториноларингологии / под ред. В.Т. Пальчуна, А.И. Крюкова, М.М. Магомедова. – М.:ГЕОТАР- Медиа, 2015. –224 с. [Guidance on focal infection in otorhinolaryngology/Ed. By V.T. Palchun, A.I. Kryukov, M.M. Magomedov. – M.: GEOTAR-Media, 2015 – 224 p].</mixed-citation><mixed-citation xml:lang="en">Руководство по очаговой инфекции в оториноларингологии / под ред. В.Т. Пальчуна, А.И. Крюкова, М.М. Магомедова. – М.:ГЕОТАР- Медиа, 2015. –224 с. [Guidance on focal infection in otorhinolaryngology/Ed. By V.T. Palchun, A.I. Kryukov, M.M. Magomedov. – M.: GEOTAR-Media, 2015 – 224 p].</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гуров А.В. Клинико-микробиологическая оценка очагов гнойно-септических заболеваний в оториноларингологии// Автореф. дисс д.м.н. М., 2011. – 53 с [Gurov A.V. Clinical and microbiological evaluation of foci of purulent and septic diseases in otorhinolaryngology// Extended abstract of PhD in medicine dissertation. M., 2011. – 53 p].</mixed-citation><mixed-citation xml:lang="en">Гуров А.В. Клинико-микробиологическая оценка очагов гнойно-септических заболеваний в оториноларингологии// Автореф. дисс д.м.н. М., 2011. – 53 с [Gurov A.V. Clinical and microbiological evaluation of foci of purulent and septic diseases in otorhinolaryngology// Extended abstract of PhD in medicine dissertation. M., 2011. – 53 p].</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Юшкина М.А. Особенности течения гнойно- воспалительных заболеваний ЛОР – органов у больных сахарным диабетом// Автореф. дис. к.м.н. М., 2012. - 25 с. [Yushkina M.A. Peculiarities of the court of purulent and inflammatory diseases of ENT-organs in diabetes mellitus patients//Extended abstract of PhD in medicine dissertation. M., 2012. – 25 p].</mixed-citation><mixed-citation xml:lang="en">Юшкина М.А. Особенности течения гнойно- воспалительных заболеваний ЛОР – органов у больных сахарным диабетом// Автореф. дис. к.м.н. М., 2012. - 25 с. [Yushkina M.A. Peculiarities of the court of purulent and inflammatory diseases of ENT-organs in diabetes mellitus patients//Extended abstract of PhD in medicine dissertation. M., 2012. – 25 p].</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chin-Hong P.V. Infections in patients with diabetes mellitus: importance of early recognition? Treatment and prevention //Adv. Stud. Med. – 2006. – Vol.6, N2. – P.71-81</mixed-citation><mixed-citation xml:lang="en">Chin-Hong P.V. Infections in patients with diabetes mellitus: importance of early recognition? Treatment and prevention //Adv. Stud. Med. – 2006. – Vol.6, N2. – P.71-81</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Оценка местного иммунитета. Пособие для врачей клинической лабораторной диагностики.// Мартынов А.И., Аршинова С.С., Симонова А.В., Андреев И.В., Будихина А.С., Мухаметзянова Т.Ж., Б.В. Пинегин. М., 2007.- 27 с [Evaluation of local immunity. Guidance for doctors of clinical laboratory diagnostics.// Martynov A.I., Arshinova S.S., Simonova A.V., Andreev I.V., Budikhina A.S., Mukhametzyanova T.Z., B.V. Pinegin. M., 2007. – 27 p].</mixed-citation><mixed-citation xml:lang="en">Оценка местного иммунитета. Пособие для врачей клинической лабораторной диагностики.// Мартынов А.И., Аршинова С.С., Симонова А.В., Андреев И.В., Будихина А.С., Мухаметзянова Т.Ж., Б.В. Пинегин. М., 2007.- 27 с [Evaluation of local immunity. Guidance for doctors of clinical laboratory diagnostics.// Martynov A.I., Arshinova S.S., Simonova A.V., Andreev I.V., Budikhina A.S., Mukhametzyanova T.Z., B.V. Pinegin. M., 2007. – 27 p].</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Пальчун В.Т., Гуров А.В., Руденко В.В. Хламидийная и микоплазменная инфекция в оториноларингологии (систематический обзор). Вестник оториноларингологии, 2012. 6. – 91-97. [Palchun V.T., Gurov A.V., Rudenko V.V. Chlamydia and Mycoplasma infection in otorhinolaryngology (systemic review)].</mixed-citation><mixed-citation xml:lang="en">Пальчун В.Т., Гуров А.В., Руденко В.В. Хламидийная и микоплазменная инфекция в оториноларингологии (систематический обзор). Вестник оториноларингологии, 2012. 6. – 91-97. [Palchun V.T., Gurov A.V., Rudenko V.V. Chlamydia and Mycoplasma infection in otorhinolaryngology (systemic review)].</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Мужичкова А.В. Клинико-морфологические особенности хронизации воспалительного процесса в верхнечелюстной пазухе// Автореф. дисс к.м.н. М., 2011. – 25 с [Muzhichkova A.V. Clinical and morphological peculiarities of inflammatory process chronization in the maxillary sinus.// Extended abstract of PhD in medicine dissertation. M., 2011. – 25 p].</mixed-citation><mixed-citation xml:lang="en">Мужичкова А.В. Клинико-морфологические особенности хронизации воспалительного процесса в верхнечелюстной пазухе// Автореф. дисс к.м.н. М., 2011. – 25 с [Muzhichkova A.V. Clinical and morphological peculiarities of inflammatory process chronization in the maxillary sinus.// Extended abstract of PhD in medicine dissertation. M., 2011. – 25 p].</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Страчунский Л.С., Белоусова Е.Б., Козлова С.Н. Антибактериальная терапия. Практическое руководство. М., 2000. – 193 с. [Strachunsky L.S., Belousov E.B., Kozlov S.N. Antibacterial therapy. Practical guidance. M., 2000. – 193 p].</mixed-citation><mixed-citation xml:lang="en">Страчунский Л.С., Белоусова Е.Б., Козлова С.Н. Антибактериальная терапия. Практическое руководство. М., 2000. – 193 с. [Strachunsky L.S., Belousov E.B., Kozlov S.N. Antibacterial therapy. Practical guidance. M., 2000. – 193 p].</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Dunbar LM, Wunderink RG, Habib MP, et al. High-dose, shortcourse levofloxacin for community-acquired pneumonia: a new treatment paradigm. Clin Infect Dis 2003;37:752–60.</mixed-citation><mixed-citation xml:lang="en">Dunbar LM, Wunderink RG, Habib MP, et al. High-dose, shortcourse levofloxacin for community-acquired pneumonia: a new treatment paradigm. Clin Infect Dis 2003;37:752–60.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Poole M, Anon J, Paglia M, et al. A trial of high dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. Otolaryngol Head Neck Surg 2006;134:10–17.</mixed-citation><mixed-citation xml:lang="en">Poole M, Anon J, Paglia M, et al. A trial of high dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. Otolaryngol Head Neck Surg 2006;134:10–17.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Klausner H.A., Brown P., Peterson J. et al. A trial of levofloxacin 750 mg once daily for 5 days versus ciprofloxacin 400 mg and/or 500 mg twice daily for 10 days in the treatment of acute pyelonephritis // Curr Med Res Opin. 2007 Nov. Vol. 23 (11). Р. 2637–2645.</mixed-citation><mixed-citation xml:lang="en">Klausner H.A., Brown P., Peterson J. et al. A trial of levofloxacin 750 mg once daily for 5 days versus ciprofloxacin 400 mg and/or 500 mg twice daily for 10 days in the treatment of acute pyelonephritis // Curr Med Res Opin. 2007 Nov. Vol. 23 (11). Р. 2637–2645.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Лучихин Л.А., Миронов А.А., Гуров А.В. Медикаментозная терапия при тяжелых гнойно-воспалительных поражениях лор-органов и их осложнениях. Вестник оториноларинго- логии, 2001. 4. 66-68 [Luchikhin L.A., Mironov A.A., Gurov A.V. Drug therapy in grave purulent and inflammatory lesions of ENT-organs and their complications. Vestnik otorinolaringologii, 2001. 4. P. 66-68].</mixed-citation><mixed-citation xml:lang="en">Лучихин Л.А., Миронов А.А., Гуров А.В. Медикаментозная терапия при тяжелых гнойно-воспалительных поражениях лор-органов и их осложнениях. Вестник оториноларинго- логии, 2001. 4. 66-68 [Luchikhin L.A., Mironov A.A., Gurov A.V. Drug therapy in grave purulent and inflammatory lesions of ENT-organs and their complications. Vestnik otorinolaringologii, 2001. 4. P. 66-68].</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
