<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2016-16-110-114</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1519</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛУБ ЭКСПЕРТОВ ESPGHAN</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ESPGHAN EXPERT CLUB</subject></subj-group></article-categories><title-group><article-title>Гастроинтестинальные проявления пищевой аллергии или функциональные нарушения желудочно-кишечного тракта принципы дифференциальной диагностики и диетотерапии</article-title><trans-title-group xml:lang="en"><trans-title>GASTROINTESTINAL MANIFESTATIONS OF FOOD ALLERGY OR FUNCTIONAL GASTROINTESTINAL DISORDERS: PRINCIPLES OF DIFFERENTIAL DIAGNOSIS  AND DIET THERAPY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ванденплас</surname><given-names>И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vandenplas</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitrieva</surname><given-names>Y. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Университетская клиника Брюсселя</institution><country>Бельгия</country></aff><aff xml:lang="en"><institution>University Hospital Brussels</institution><country>Belgium</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российская медицинская академия последипломного образования, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>16</issue><fpage>110</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ванденплас И., Захарова И.Н., Дмитриева Ю.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Ванденплас И., Захарова И.Н., Дмитриева Ю.А.</copyright-holder><copyright-holder xml:lang="en">Vandenplas I., Zakharova I.N., Dmitrieva Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1519">https://www.med-sovet.pro/jour/article/view/1519</self-uri><abstract><p>В течение последних лет в России, как и во всем мире, отмечен отчетливый рост проявлений пищевой аллергии у младенцев. К сожалению, до сих пор не сформировано четкое представление у врачей-педиатров о том, что гастроинтестинальные проявления пищевой аллергии распространены не менее, чем кожные.</p></abstract><trans-abstract xml:lang="en"><p>The incidence of food allergy manifestations in infants has steadily grown over the past years both in Russia and worldwide. Unfortunately, there is still no clear understanding among pediatricians that gastrointestinal manifestations of food allergy are no less common than skin manifestations.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пищевая аллергия</kwd><kwd>белок коровьего молока</kwd><kwd>гастроинтестинальные  проявления</kwd><kwd>дети грудного возраста</kwd><kwd>протокол ESPGHAN</kwd><kwd>элиминационная диета</kwd><kwd>аминокислотные смеси</kwd><kwd>смеси на основе частично гидролизованного белка</kwd><kwd>смеси на основе полностью гидролизованного белка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>food allergy</kwd><kwd>cow’s milk protein</kwd><kwd>gastrointestinal manifestations</kwd><kwd>infants</kwd><kwd>ESPGHAN protocol</kwd><kwd>elimination diet</kwd><kwd>amino acidbased formula</kwd><kwd>partially hydrolyzed formula</kwd><kwd>extensively hydrolysed formulas</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sicherer SH. Epidemiology of food allergy. J Allergy Clin Immunol, 2011 Mar, 127(3): 594-602,</mixed-citation><mixed-citation xml:lang="en">Sicherer SH. Epidemiology of food allergy. J Allergy Clin Immunol, 2011 Mar, 127(3): 594-602,</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Rona RJ, Keil T, Summers C et al. The prevalence of food allergy: A meta-analysis. J Allergy Clin Immunol, 2007, 120(3): 638-646.</mixed-citation><mixed-citation xml:lang="en">Rona RJ, Keil T, Summers C et al. The prevalence of food allergy: A meta-analysis. J Allergy Clin Immunol, 2007, 120(3): 638-646.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Koletzko S, Isolauri E, Hill D, Oranje AP, Brueton M, Staiano A, Dupont C. Guidelines for the diagnosis and management of cow’s milk protein allergy in infants. Arch Dis Child, 2007, 92: 902-8.</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Koletzko S, Isolauri E, Hill D, Oranje AP, Brueton M, Staiano A, Dupont C. Guidelines for the diagnosis and management of cow’s milk protein allergy in infants. Arch Dis Child, 2007, 92: 902-8.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Koletzko S, Niggemann B, Arato A et al. Diagnostic approach and management of cow’s-milk protein allergy in infants and children: ESPGHAN GI Committee practical guidelines. J Pediatr Gastroenterol Nutr, 2012 Aug, 55(2): 221-9.</mixed-citation><mixed-citation xml:lang="en">Koletzko S, Niggemann B, Arato A et al. Diagnostic approach and management of cow’s-milk protein allergy in infants and children: ESPGHAN GI Committee practical guidelines. J Pediatr Gastroenterol Nutr, 2012 Aug, 55(2): 221-9.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Eggesbo M, Botten G, Halvorsen R, Magnus P. The prevalence of CMA/CMPI in young children: the validity of parentally perceived reactions in a population-based study. Allergy, 2001 May, 56(5): 393-402.</mixed-citation><mixed-citation xml:lang="en">Eggesbo M, Botten G, Halvorsen R, Magnus P. The prevalence of CMA/CMPI in young children: the validity of parentally perceived reactions in a population-based study. Allergy, 2001 May, 56(5): 393-402.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Schouten B, van Esch BC, van Thuijl AO et al. Contribution of IgE and immunoglobulin free light chain in the allergic reaction to cow’s milk proteins. J Allergy Clin Immunol, 2010, 125: 1308-14.</mixed-citation><mixed-citation xml:lang="en">Schouten B, van Esch BC, van Thuijl AO et al. Contribution of IgE and immunoglobulin free light chain in the allergic reaction to cow’s milk proteins. J Allergy Clin Immunol, 2010, 125: 1308-14.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Gottrand F, Veereman-Wauters G et al. Gastro-intestinal manifestations of cow’s milk protein allergy and gastro-intestinal motility. Acta Paediatr, 2012 Nov, 101(11): 1105-9.</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Gottrand F, Veereman-Wauters G et al. Gastro-intestinal manifestations of cow’s milk protein allergy and gastro-intestinal motility. Acta Paediatr, 2012 Nov, 101(11): 1105-9.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Buisseret PD. Common manifestations of CMA in children. Lancet, 1978, 8059: 304-5.</mixed-citation><mixed-citation xml:lang="en">Buisseret PD. Common manifestations of CMA in children. Lancet, 1978, 8059: 304-5.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Forget P, Arends JW. Cow’s milk protein allergy and gastro-oesophageal reflux. Eur J Pediatr, 1985, 144: 298-300.</mixed-citation><mixed-citation xml:lang="en">Forget P, Arends JW. Cow’s milk protein allergy and gastro-oesophageal reflux. Eur J Pediatr, 1985, 144: 298-300.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsen RG, Bindslev-Jensen C, Kruse-Andersen S, Husby S. Severe gastro-esophageal reflux disease and cow milk hypersensitivity in infants and children: disease association and evaluation of a new challenge procedure. J Pediatr Gastroenterol Nutr, 2004, 9: 383-91.</mixed-citation><mixed-citation xml:lang="en">Nielsen RG, Bindslev-Jensen C, Kruse-Andersen S, Husby S. Severe gastro-esophageal reflux disease and cow milk hypersensitivity in infants and children: disease association and evaluation of a new challenge procedure. J Pediatr Gastroenterol Nutr, 2004, 9: 383-91.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Ravelli AM, Tobanelli P, Volpi S, Ugazio AG. Vomiting and gastric motility in infants with cow’s milk allergy. J Pediatr Gastroenterol Nutr, 2001, 32: 59-64.</mixed-citation><mixed-citation xml:lang="en">Ravelli AM, Tobanelli P, Volpi S, Ugazio AG. Vomiting and gastric motility in infants with cow’s milk allergy. J Pediatr Gastroenterol Nutr, 2001, 32: 59-64.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Borelli O, Mancini V, Thapar N, Giorgio V, Elawad M, Hill S, Shah N, Lindley KJ. Cow’s milk challenge increases weakly acidic reflux in children with cow’s milk allergy and gastroesophageal reflux. J Pediatr, 2012 Sep, 161(3): 476-481.</mixed-citation><mixed-citation xml:lang="en">Borelli O, Mancini V, Thapar N, Giorgio V, Elawad M, Hill S, Shah N, Lindley KJ. Cow’s milk challenge increases weakly acidic reflux in children with cow’s milk allergy and gastroesophageal reflux. J Pediatr, 2012 Sep, 161(3): 476-481.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">De Boissieu D, Matarazzo P, Dupont C. Allergy to extensively hydrolyzed cow’s milk proteins in infants: safety and duration of amino acid-based formula. J Pediatr, 2002 Aug, 141(2): 271-3.</mixed-citation><mixed-citation xml:lang="en">De Boissieu D, Matarazzo P, Dupont C. Allergy to extensively hydrolyzed cow’s milk proteins in infants: safety and duration of amino acid-based formula. J Pediatr, 2002 Aug, 141(2): 271-3.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y, Rudolph CD, Di Lorenzo et al. North American Society for Pediatric Gastroenterology Hepatology and Nutrition, European Society for Pediatric Gastroenterology Hepatology and Nutrition. Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN). J Pediatr Gastroenterol Nutr, 2009, 49: 498-547.</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y, Rudolph CD, Di Lorenzo et al. North American Society for Pediatric Gastroenterology Hepatology and Nutrition, European Society for Pediatric Gastroenterology Hepatology and Nutrition. Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN). J Pediatr Gastroenterol Nutr, 2009, 49: 498-547.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
