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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2016-11-52-56</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1541</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПАРКИНСОНИЗМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PARKINSONISM</subject></subj-group></article-categories><title-group><article-title>АМАНТАДИНЫ: ОПЫТ ПРИМЕНЕНИЯ ПРИ БОЛЕЗНИ ПАРКИНСОНА</article-title><trans-title-group xml:lang="en"><trans-title>AMANTADINES: EXPERIENCE OF APPLICATION FOR PARKINSON DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ПИЛИПОВИЧ</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>PILIPOVICH</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ГОЛУБЕВ</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>GOLUBEV</surname><given-names>V. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>11</issue><fpage>52</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; ПИЛИПОВИЧ А.А., ГОЛУБЕВ В.Л., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">ПИЛИПОВИЧ А.А., ГОЛУБЕВ В.Л.</copyright-holder><copyright-holder xml:lang="en">PILIPOVICH A.A., GOLUBEV V.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1541">https://www.med-sovet.pro/jour/article/view/1541</self-uri><abstract><p>В статье описывается зарубежный и отечественный опыт применения амантадина и препарата ПК-Мерц при болезни Паркинсона в качестве монотерапии и комплексного лечения. Приводятся данные основных плацебо-контролируемых исследований эффективности и безопасности препаратов данной группы.</p></abstract><trans-abstract xml:lang="en"><p>The article provides the foreign and domestic experience of amantadine application and PK-Merz use for Parkinson disease as monotherapy and within complex therapy. Data of major placebo-controlled effectiveness and safety studies of drugs of this groups are provided ПК.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ПК-Мерц</kwd><kwd>амантадин</kwd><kwd>болезнь Паркинсона</kwd><kwd>экстрапирамидные расстройства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>PK-Merz</kwd><kwd>amantadine</kwd><kwd>Parkinson disease</kwd><kwd>extrapyramidal disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Карабань И.Н., Карабань Н.В., Карасевич Н.В. 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