medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2015-12-18-23medsovet-1607Research ArticleАРТЕРИАЛЬНАЯ ГИПЕРТЕНЗИЯARTERIAL HYPERTENSIONКомбинированная терапия артериальной гипертензииCombination therapy of hypertensionБольшаковаО. О.BolshakovaO. O.noemail@neicon.ruСеверо-Западный федеральный медицинский исследовательский центр им. В.А. Алмазова Минздрава России, Санкт-ПетербургРоссияAlmazov Federal North-West Medical Research Centre, Ministry of Health of the Russian Federation, St. PetersburgRussian Federation2015301220150121823Copyright © Большакова О.О., 20152015Большакова О.О.Bolshakova O.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/1607

Статья представляет собой краткий обзор литературных данных, касающихся назначения комбинированной антигипертензивной терапии. Особое внимание уделяется доказательной базе применения фиксированной комбинации лерканидипина и эналаприла, для которой характерны высокая антиги-пертензивная эффективность, низкий уровень побочных эффектов, доказанное органопротективное (прежде всего, нефропротективное) действие и отсутствие негативного влияния на обмен липидов и глюкозы, что позволяет использовать данную комбинацию в любых возрастных группах пациентов, а также у больных, относящихся к группам высокого сердечно-сосудистого риска.

The article is a short overview of articles related to the prescription of combination antihypertensive therapy. The focus is on the evidence of administration of a fixed combination - lercanidipine plus enalapril, which is characterized by a high antihypertensive efficacy, low rate of side effects, a proven organoprotective (primarily nephroprotective) action and absence of negative impact on lipid and glucose metabolism. This allows to prescribe this combination to patients in all age groups as well as patients at high cardiovascular risk.

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The authors declare that there are no conflicts of interest present.