medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2015-12-84-93medsovet-1617Research ArticleПРОФИЛАКТИКА ИНСУЛЬТАSTROKE PREVENTIONЭффективность аторвастатина при профилактике инсультаThe effectiveness of atorvastatin in the prevention of strokeОстроумоваО. Д.OstroumovaO. D.noemail@neicon.ruКопченовИ. И.KopchenovI. I.noemail@neicon.ruГусеваТ. Ф.GusevaТ. F.noemail@neicon.ruБондарецО. В.BondaretsO. V.noemail@neicon.ruЩукинаГ. Н.SchukinaG. N.noemail@neicon.ruМосковский государственный медико-стоматологический университет им. А.И. Евдокимова; Первый Московский государственный медицинский университет им. И.М. СеченоваРоссияMoscow State University of Medicine and Dentistry named after A.I. Evdokimov; First Moscow State Medical University named after I.M. SechenovRussian FederationМосковский государственный медико-стоматологический университет им. А.И. ЕвдокимоваРоссияMoscow State University of Medicine and Dentistry named after A.I. EvdokimovRussian Federation2015301220150128493Copyright © Остроумова О.Д., Копченов И.И., Гусева Т.Ф., Бондарец О.В., Щукина Г.Н., 20152015Остроумова О.Д., Копченов И.И., Гусева Т.Ф., Бондарец О.В., Щукина Г.Н.Ostroumova O.D., Kopchenov I.I., Guseva Т.F., Bondarets O.V., Schukina G.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/1617

В статье рассмотрена взаимосвязь риска развития инсульта с различными параметрами липидного обмена. Приведены данные, свидетельствующие о том, что только статины, в отличие от ряда других гиполипидемических препаратов, достоверно снижают риск развития как первого, так и повторного инсульта. Обсуждаются данные исследований, в которых было получено снижение риска развития церебральных событий на фоне применения аторвастатина. Подчеркивается, что при назначении гене-рических препаратов одинаковая степень эффективности и безопасности гарантирована только в случае доказанной терапевтической эквивалентности оригинальному препарату.

Summary. The article examined the relationship between the risk of stroke and various profiles of lipid metabolism. The findings show that only statins, unlike many other lipid-lowering drugs, significantly reduce the risk of both primary and recurrent stroke. The discussion is focused on research findings demonstrating a lower risk of cerebral events during treatment with atorvastatin. It is stressed that in case of administration of generic drugs, the same level of efficiency and safety can only be guaranteed if the generic has a proven therapeutic equivalence to the original drug.

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The authors declare that there are no conflicts of interest present.