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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2015-12-94-103</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1618</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИСЛИПИДЕМИИ И АТЕРОСКЛЕРОЗ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DYSLIPIDEMIA AND ATHEROSCLEROSIS</subject></subj-group></article-categories><title-group><article-title>Современные подходы в лечении дислипидемий: от научных дискуссий к конкретному больному</article-title><trans-title-group xml:lang="en"><trans-title>Current approaches to the treatment of dyslipidemia: from scholarly disputes to the individual patient</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сусеков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Susekov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский кардиологический научно-производственный комплекс Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Cardiology Research and Production Complex, Ministry of Health of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2015</year></pub-date><volume>0</volume><issue>12</issue><fpage>94</fpage><lpage>103</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сусеков А.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Сусеков А.В.</copyright-holder><copyright-holder xml:lang="en">Susekov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1618">https://www.med-sovet.pro/jour/article/view/1618</self-uri><abstract><p>Нарушения липидного обмена, и в первую очередь повышение в плазме крови уровня холестерина липопротеинов низкой плотности (ХС-ЛНП), положительно коррелируют с частотой и количеством сердечно-сосудистых осложнений - инфарктов миокарда и ишеми-ческих инсультов [1-7]. Рандомизированные исследования со статинами и серия метаанализов клинических исследований с этими препаратами Cholesterol Treatment Trialist (CTT) Collaboration 2005, 2010, 2012 гг. продемонстрировали тесную связь между снижением уровня «плохого» холестерина на терапии статинами и уменьшением количества сердечнососудистых (СС) осложнений [8, 9]. В Российской Федерации, несмотря на достижения профилактической кардиологии последних лет, показатели сердечно-сосудистой и общей смертности остаются высокими. Ежегодно в России от заболеваний системы кровообращения умирает более 1 млн человек, доля СС-заболеваний в структуре общей смертности превышает 50% [5-7]. По сравнению с другими развитыми и развивающимися странами средняя продолжительность жизни в РФ, по данным ВОЗ, остается низкой и составляет в среднем 66 лет. В частности, по данным ВОЗ, 2013 г. средняя продолжительность граждан России невысока и составляет в среднем 66,05 года в целом, у мужчин - 59,1 года, у женщин - 73 года. Мы занимаем 129-е место в списке всех стран - между Гайаной и Багамами (рис. 1). Одним из важнейших задач снижения СС-смерт-ности в нашей стране является адекватный контроль ключевых факторов СС-риска (сахарный диабет, курение, артериальная гипертония и дислипи-демия) [7, 10]</p></abstract><trans-abstract xml:lang="en"><p>Lipid metabolism, and especially increased plasma levels of low-density lipoprotein cholesterol (LDLC), are positively correlated with the incidence and number of cardiovascular events - heart attacks and ischemic strokes. [1--7] Randomized trials of statins and a series of meta-analyses of statin trials - Cholesterol Treatment Trialists' (STT) Collaboration 2005, 2010, 2012 - demonstrated a close relationship between decrease in the "bad" cholesterol level on statin therapy and decrease in the number of cardiovascular (CV) complications. [8, 9] In the Russian Federation, despite advances in preventive cardiology in recent years, cardiovascular and total mortality rates remain high. Circulatory system diseases cause death of more than 1 million people in Russia annually; CS diseases account for more than 50% in the structure of total mortality. [5--7] Compared with other developed and developing countries, life expectancy in the Russian Federation, according to the WHO, remains low equalling an average of 66 years. Specifically in 2013, according to the WHO, average life expectancy of Russian people was low equalling an average of 66.05 in general, 59.1 years for men and 73 years for women. We are on the 129th place in the total list of countries, between Guyana and the Bahamas (Slide 1). One of the most challenging tasks in reducing CV mortality in this country is adequate monitoring of the key CV risk factors (diabetes, smoking, hypertension and dyslipidemia)</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285(19): 2486-2497.</mixed-citation><mixed-citation xml:lang="en">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. 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