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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-1-45-50</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1677</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕОНАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEONATOLOGY</subject></subj-group></article-categories><title-group><article-title>РОЛЬ ЭМОЛЕНТОВ В ПАТОГЕНЕТИЧЕСКОЙ ТЕРАПИИ АТОПИЧЕСКОГО ДЕРМАТИТА У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>The role of emollients in pathogenetic therapy of atopic dermatitis in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaytseva</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in Medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry named after A.I. Evdokimov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><fpage>45</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зайцева С.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Зайцева С.В.</copyright-holder><copyright-holder xml:lang="en">Zaytseva S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1677">https://www.med-sovet.pro/jour/article/view/1677</self-uri><abstract><p>Атопический дерматит (АтД) является наиболее распространенным воспалительным заболеванием кожи в детском возрасте. В практическом здравоохранении основным механизмом развития АтД является пищевая аллергия у детей. Однако, как показали современные исследования, значительное место в патогенезе АтД занимает нарушение строения элементов кожного барьера, что способствует ксерозу кожи и повышению проницаемости его для аллергенов. Соответственно, терапия АтД должна быть направлена не только на купирование аллергических реакций, но и на восстановление и поддержание целостности кожного барьера. Основная роль в этом отводится использованию средств, восстанавливающих липидный состав эпидермиса, – эмолентам. Среди данной группы средств можно отметить крем-эмульсию Stelatopia, эффективность которой установлена в ходе клинических исследований при лечении АтД у детей. </p></abstract><trans-abstract xml:lang="en"><p>Atopic dermatitis (AtD) is the most common inflammatory skin disease in childhood. In practical healthcare, the basic mechanism for the development of AtD in children is food allergy. However, recent studies demonstrate that disruptions of the skin barrier structure play a relevant role in the pathogenesis of AtD, contributing to xeroderma and increased skin permeability to allergens. Accordingly, AtD therapy should be targeted not only at relief of allergic reactions but also at restoration and maintenance of the skin barrier integrity. The key role here belongs to agents that restore epidermal lipid content – emollients. Among representatives of the group of treatments, the effectiveness of Stelatopia moisturizing emulsion for the treatment of atopic dermatitis in children was confirmed by clinical trials. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>атопический дерматит</kwd><kwd>кожный барьер</kwd><kwd>эмоленты</kwd><kwd>Stelatopia</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atopic dermatitis</kwd><kwd>skin barrier</kwd><kwd>emollients</kwd><kwd>Stelatopia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Белоусова Т.А., Горячкина М.В. Современные представления о структуре и функции кожного барьера и терапевтические возможности коррекции его нарушений. РМЖ, 2004, 18: 1082-1085.</mixed-citation><mixed-citation xml:lang="en">Белоусова Т.А., Горячкина М.В. Современные представления о структуре и функции кожного барьера и терапевтические возможности коррекции его нарушений. 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