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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-2-26-30</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1717</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая лекция</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical lecture</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ ВОЗМОЖНОСТИ ЛЕЧЕНИЯ АНЕМИИ У БЕРЕМЕННЫХ ЖЕНЩИН (ЛЕКЦИЯ)</article-title><trans-title-group xml:lang="en"><trans-title>CURRENT TREATMENT OPTIONS FOR ANEMIA IN PREGNANT WOMEN (LECTURE)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернов</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernov</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, </p><p>Москва</p></bio><bio xml:lang="en"><p>MD, PhD, </p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н.,</p><p>Москва</p></bio><bio xml:lang="en"><p>Professor,</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный научно-практический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный научно-практический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России;&#13;
Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev;&#13;
Russian National Research Medical University named after N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2017</year></pub-date><volume>0</volume><issue>2</issue><fpage>26</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чернов В.М., Тарасова И.С., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Чернов В.М., Тарасова И.С.</copyright-holder><copyright-holder xml:lang="en">Chernov V.M., Tarasova I.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1717">https://www.med-sovet.pro/jour/article/view/1717</self-uri><abstract><p>Анемия может выявляться у женщин до беременности, во время беременности, после родов, в период лактации, что требует внимания врачей и динамического клинического и лабораторного наблюдения. Большинство анемий у беременных женщин являются железодефицитными (ЖДА). Необходима правильная диагностики, т. к. возможны и другие анемии (постгеморрагическая, фолиево-дефицитная, анемия при хронических заболеваниях). Современными возможностями лечения ЖДА являются применение пероральных препаратов железа (у 90% беременных женщин), внутривенных препаратов железа (у 10% беременных женщин), при- менение эритропоэзстимулирующих препаратов (ЭСП) (у 2% беременных женщин) и трансфузии эритроцитов в тяжелых случаях (у 3% беременных женщин). Описана история создания железо-углеводных комплексов в лаборатории C.F. Hausmann. Приводятся свойства различных внутривенных препаратов железа в историческом аспекте их создания (глюконат, декстран, сахарат, карбоксимальтозат железа) и преодоление нежелательных явлений. Показаниями к применению внутривенных препаратов железа являются: ЖДА тяжелой степени, неэффективность или непереносимость пероральных препаратов железа, наличие язвенной болезни желудка или двенадцатиперстной кишки или операций на желудочно-кишечном тракте, наличие противопоказаний к трансфузии эритроцитов, лечение ЭСП. Преимуществами внутривенного препарата карбоксимальтозата железа являются: возможность применения в высокой дозе (до 1000 мг 1 раз в неделю), отсутствие необходимости в тест-дозе, возможность введения за 15 мин. Показаны высокая эффективность, хорошая переносимость карбоксимальтозата железа в лечении ЖДА. Фармакоэкономический анализ показал целесообразность его применения по сравнению с препаратом предыдущего поколения  – сахаратом железа. Применение внутривенных препаратов железа в лечении ЖДА у беременных женщин позволит минимизировать количество переливаний эритроцитов и перейти на этап препаратной заместительной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Anemia can be detected in women before pregnancy, during pregnancy, after childbirth, during lactation period, requiring the attention of doctors and clinical and laboratory monitoring. Iron deficiency anemia (IDA) is the most common anemia in pregnant women. Accurate diagnosis is needed, since there are other possible anemias (posthemorrhagic, folate deficiency, anemia of chronic diseases). Modern options of IDA treatment are include the use of oral iron preparations (in 90% of pregnant women), intravenous iron preparations (in 10% of pregnant women), erythropoiesis stimulating agents – ESA (in 2% of pregnant women), and red blood cell transfusions in severe cases (in 3% of pregnant women). The history of creation of intravenous iron complexes in the laboratory of C.F. Hausmann, as well as properties of various intravenous iron complex formulations in the historical aspect of their manufacturing process (ferric gluconate, iron dextran, iron sucrose, ferric carboxymaltose) and the negotiation of adverse events are described. Indications for the use of intravenous iron preparations are the following: severe IDA, ineffectiveness or intolerance of oral iron, the presence of gastric or duodenal ulcer or gastrointestinal surgery in the past, contraindications for red blood cell transfusions, use of ESA. The advantages of intravenous ferric carboxymaltose are the possibility to use the high dose of iron preparation (1000 mg, 1 time per week), no need for test dose, the possibility of intravenous administration in 15 minutes. High efficiency, good tolerability of ferric carboxymaltose in the treatment of IDA are shown. Pharmacoeconomic analysis showed the feasibility of administration of ferric carboxymaltose in comparison with the drug of previous generation (iron sucrose). The use of intravenous iron preparations in the treatment of IDA in pregnant women will allow to minimize red blood cell transfusions and to move to the stage of drug replacement therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременные женщины</kwd><kwd>железодефицитная анемия</kwd><kwd>лечение</kwd><kwd>препараты железа</kwd><kwd>внутривенные препараты железа</kwd><kwd>показания</kwd><kwd>эффективность</kwd><kwd>карбоксимальтозат железа</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnant women</kwd><kwd>iron deficiency anemia</kwd><kwd>treatment</kwd><kwd>iron preparations</kwd><kwd>intravenous iron preparations</kwd><kwd>indications</kwd><kwd>effectiveness</kwd><kwd>ferric carboxymaltose</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Хух Р., Брейман К. Анемия во время беременности и в послеродовом периоде. Пер. с англ. 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