medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2017-2-46-47medsovet-1720Research ArticleБеременность и родыPregnancy and childbirthПЛАНИРОВАНИЕ БЕРЕМЕННОСТИ. ДЕФИЦИТ ВИТАМИНА Д – БЕСПЛОДИЕ, КОРРЕКЦИЯ ДЕФИЦИТА ВИТАМИНА ДPREGNANCY PLANNING. VITAMIN D DEFICIT – INFERTILITY, CORRECTION OF VITAMIN D DEFICITЯзыковаО. И.YazykovaO. I.

Москва

Moscow

ХилькевичЕ. Г.KhilkevichE. G.

д.м.н., профессор,

Москва

MD, Prof.,

Moscow

Научный центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова Минздрава РоссииРоссияAcademician Kulakov Scientific Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of RussiaRussian Federation201730122017024647Copyright © Языкова О.И., Хилькевич Е.Г., 20172017Языкова О.И., Хилькевич Е.Г.Yazykova O.I., Khilkevich E.G.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/1720Цель исследования

Цель исследования. Изучить эффективность применения препаратов витамина D на этапе планирования беременности у женщин с бесплодием различной этиологии по данным отечественной и зарубежной литературы.

Материал и методы

Материал и методы. По ключевым словам «витамин D», «бесплодие», «прегравидарная подготовка» нами проведен поиск литературных источников в отечественных и зарубежных базах данных: Еlibrary, Medline/PubMed, Embase, CINAHL. Отобрано 23 источника.

Результаты исследования

Результаты исследования. Витамин D играет важную роль в регуляции менструального цикла и поддержании репродуктивного здоровья женщины. Распространенность дефицита витамина D среди женщин с бесплодием различной этиологии достигает 69%. Необходимым является достижение адекватного уровня витамина D в организме женщины и проведение профилактики его дефицита.

Заключение

Заключение. Всем женщинам с бесплодием на этапе подготовки к беременности рекомендуется проведение оценки достаточности витамина D путем определения 25(OH)D в сыворотке крови и коррекция его дефицита до достижения уровней 25(OH)D более 30 нг/мл. 

Study objective

Study objective. To study the efficacy of the drugs vitamin D at the stage of planning of pregnancy in women with infertility of various etiologies, according to domestic and foreign literature.

Materials and methods

Materials and methods. We conducted a search of the literature sources by the keywords “vitamin D”, “infertility”, “pregravid preparation” in domestic and foreign databases: elibrary, Medline/PubMed, Embase, CINAHL. 23 sources were selected.

Study results

Study results. Vitamin D plays an important role in the regulation of the menstrual cycle and the reproductive health of women. The prevalence of vitamin D deficiency among women with infertility of various etiologies reaches 69%. It is vital to achieve an adequate level of vitamin D in a woman’s body and to prevent its deficiency.

Conclusion

Conclusion. For all women with infertility at the stage of preparation it is recommended to conduct assessment of adequacy of vitamin D by determination of 25(OH)D in serum and correction of its deficit to achieve levels of 25(OH)D more than 30 ng/ml. 

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The authors declare that there are no conflicts of interest present.