<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-7-43-47</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1768</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТРОМБОЗЫ И ТРОМБОЭМБОЛИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>THROMBOSIS AND THROMBOEMBOLISM</subject></subj-group></article-categories><title-group><article-title>ПРОФИЛАКТИКА ВЕНОЗНЫХ ТРОМБОЭМБОЛИЧЕСКИХ ОСЛОЖНЕНИЙ В ТЕРАПЕВТИЧЕСКОЙ ПРАКТИКЕ</article-title><trans-title-group xml:lang="en"><trans-title>PREVENTION OF VENOUS THROMBOEMBOLIC COMPLICATIONS IN PRIMARY CARE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шилова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilova</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical University named after I.M. Sechenov, MoH RF</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2017</year></pub-date><volume>0</volume><issue>7</issue><fpage>43</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Новикова Н.А., Шилова А.С., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Новикова Н.А., Шилова А.С.</copyright-holder><copyright-holder xml:lang="en">Novikova N.A., Shilova A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1768">https://www.med-sovet.pro/jour/article/view/1768</self-uri><abstract><p>Венозные тромбоэмболические осложнения остаются значимой причиной смертности и инвалидизации у госпитализированных больных как в хирургической, так и в терапевтической практике во всем мире, несмотря на то, что медикаментозные и механические способы профилактики известны уже несколько десятилетий.</p></abstract><trans-abstract xml:lang="en"><p>Venous thromboembolic complications remain a widespread cause of mortality and disability in hospitalized patients both in surgery and primary care all over the world, despite the fact that medical and mechanical methods of prevention have been known for several decades.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>венозные тромбоэмболические осложнения</kwd><kwd>тромбоз глубоких вен</kwd></kwd-group><kwd-group xml:lang="en"><kwd>venous thromboembolic complications</kwd><kwd>deep vein thrombosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bergmann JF, Cohen AT, Tapson VF, Goldhaber SZ, Kakkar AK, Deslandes B et al. Venous thromboembolism risk and prophylaxis in hospitalised medically ill patients. The ENDORSE Global Survey. Thromb Haemost, 2010, 103(4): 736-48.</mixed-citation><mixed-citation xml:lang="en">Bergmann JF, Cohen AT, Tapson VF, Goldhaber SZ, Kakkar AK, Deslandes B et al. Venous thromboembolism risk and prophylaxis in hospitalised medically ill patients. The ENDORSE Global Survey. Thromb Haemost, 2010, 103(4): 736-48.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen AT, Tapson VF, Bergmann JF, Goldhaber SZ, Kakkar AK, Deslandes B, et al. Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study. Lancet, 2008, 371(9610): 387-94.</mixed-citation><mixed-citation xml:lang="en">Cohen AT, Tapson VF, Bergmann JF, Goldhaber SZ, Kakkar AK, Deslandes B, et al. Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study. Lancet, 2008, 371(9610): 387-94.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Dentali F, Donadini M, Gianni M, Bertolini A, Squizzato A, Venco A et al. Incidence of chronic pulmonary hypertension in patients with previous pulmonary embolism. Thromb Res, 2009, 124(3): 256-8.</mixed-citation><mixed-citation xml:lang="en">Dentali F, Donadini M, Gianni M, Bertolini A, Squizzato A, Venco A et al. Incidence of chronic pulmonary hypertension in patients with previous pulmonary embolism. Thromb Res, 2009, 124(3): 256-8.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Karwinski B, Svendsen E. Comparison of clinical and postmortem diagnosis of pulmonary embolism. J Clin Pathol, 1989, 42(2): 135-9.</mixed-citation><mixed-citation xml:lang="en">Karwinski B, Svendsen E. Comparison of clinical and postmortem diagnosis of pulmonary embolism. J Clin Pathol, 1989, 42(2): 135-9.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Sweetland S, Green J, Liu B, Berrington de Gonzalez A, Canonico M, Reeves G et al. Duration and magnitude of the postoperative risk of venous thromboembolism in middle aged women: prospective cohort study. BMJ, 2009, 339: b4583.</mixed-citation><mixed-citation xml:lang="en">Sweetland S, Green J, Liu B, Berrington de Gonzalez A, Canonico M, Reeves G et al. Duration and magnitude of the postoperative risk of venous thromboembolism in middle aged women: prospective cohort study. BMJ, 2009, 339: b4583.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Goldhaber SZ, Ridker PM. Thrombosis and Thromboembolism. New York, NY: Marcel Dekker, Inc, 2002.</mixed-citation><mixed-citation xml:lang="en">Goldhaber SZ, Ridker PM. Thrombosis and Thromboembolism. New York, NY: Marcel Dekker, Inc, 2002.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Geerts WH, Heit JA, Clagett GP et al. Prevention of venous thromboembolism. Chest, 2001, 119: 132S–175S.</mixed-citation><mixed-citation xml:lang="en">Geerts WH, Heit JA, Clagett GP et al. Prevention of venous thromboembolism. Chest, 2001, 119: 132S–175S.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Goldhaber SZ, Savage DD, Garrison RJ, Castelli WP, Kannel WB, McNamara PM et al. Risk factors for pulmonary embolism. The Framingham Study. Am J Med, 1983, 74(6): 1023-8.</mixed-citation><mixed-citation xml:lang="en">Goldhaber SZ, Savage DD, Garrison RJ, Castelli WP, Kannel WB, McNamara PM et al. Risk factors for pulmonary embolism. The Framingham Study. Am J Med, 1983, 74(6): 1023-8.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kucher N, Koo S, Quiroz R et al. Electronic Alerts to Prevent Venous Thromboembolism among Hospitalized Patients. N Engl J Med, 2005, 352: 969-977.</mixed-citation><mixed-citation xml:lang="en">Kucher N, Koo S, Quiroz R et al. Electronic Alerts to Prevent Venous Thromboembolism among Hospitalized Patients. N Engl J Med, 2005, 352: 969-977.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Alikhan R, Cohen AT. Heparin for the prevention of venous thromboembolism in general medical patients (excluding stroke and myocardial infarction). Cochrane Database of Systematic Reviews, 2009.</mixed-citation><mixed-citation xml:lang="en">Alikhan R, Cohen AT. Heparin for the prevention of venous thromboembolism in general medical patients (excluding stroke and myocardial infarction). Cochrane Database of Systematic Reviews, 2009.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hirsh J, Warkentin TE, Shaughnessy SG, Anand SS, Halperin JL, Raschke R et al. Heparin and lowmolecular-weight heparin: mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety. Chest, 2001, 119(1 Suppl): 64S-94S.</mixed-citation><mixed-citation xml:lang="en">Hirsh J, Warkentin TE, Shaughnessy SG, Anand SS, Halperin JL, Raschke R et al. Heparin and lowmolecular-weight heparin: mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety. Chest, 2001, 119(1 Suppl): 64S-94S.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Boneu B. Low molecular weight heparin therapy: is monitoring needed? Thromb Haemost, 1994, 72(3): 330-4.</mixed-citation><mixed-citation xml:lang="en">Boneu B. Low molecular weight heparin therapy: is monitoring needed? Thromb Haemost, 1994, 72(3): 330-4.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Dunn AS, Brenner A, Halm EA. The magnitude of an iatrogenic disorder: a systematic review of the incidence of venous thromboembolism for general medical inpatients. Thromb Haemost, 2006, 95(5): 758-62.</mixed-citation><mixed-citation xml:lang="en">Dunn AS, Brenner A, Halm EA. The magnitude of an iatrogenic disorder: a systematic review of the incidence of venous thromboembolism for general medical inpatients. Thromb Haemost, 2006, 95(5): 758-62.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Vessey M, Mant D, Smith A, Yeates D. Oral contraceptives and venous thromboembolism: findings in a large prospective study. Br Med J (Clin Res Ed), 1986, 292(6519): 526.</mixed-citation><mixed-citation xml:lang="en">Vessey M, Mant D, Smith A, Yeates D. Oral contraceptives and venous thromboembolism: findings in a large prospective study. Br Med J (Clin Res Ed), 1986, 292(6519): 526.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Antiplatelet Trialists’ Collaboration. Collaborative overview of randomised trials of antiplatelet therapy–III: Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients. Antiplatelet Trialists’ Collaboration. BMJ, 1994, 308(6923): 235-46.</mixed-citation><mixed-citation xml:lang="en">Antiplatelet Trialists’ Collaboration. Collaborative overview of randomised trials of antiplatelet therapy–III: Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients. Antiplatelet Trialists’ Collaboration. BMJ, 1994, 308(6923): 235-46.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Wein L, Wein S, Haas SJ, Shaw J, Krum H. Pharmacological venous thromboembolism prophylaxis in hospitalized medical patients: a meta-analysis of randomized controlled trials. Arch Intern Med, 2007, 167(14): 1476-86.</mixed-citation><mixed-citation xml:lang="en">Wein L, Wein S, Haas SJ, Shaw J, Krum H. Pharmacological venous thromboembolism prophylaxis in hospitalized medical patients: a meta-analysis of randomized controlled trials. Arch Intern Med, 2007, 167(14): 1476-86.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Alikhan R, Cohen AT. Heparin for the prevention of venous thromboembolism in general medical patients (excluding stroke and myocardial infarction). Cochrane Database of Systematic Reviews, 2009.</mixed-citation><mixed-citation xml:lang="en">Alikhan R, Cohen AT. Heparin for the prevention of venous thromboembolism in general medical patients (excluding stroke and myocardial infarction). Cochrane Database of Systematic Reviews, 2009.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ginzburg E, Cohn SM, Lopez J, Jackowski J, Brown M, Hameed SM et al. Randomized clinical trial of intermittent pneumatic compression and low molecular weight heparin in trauma. Br J Surg, 2003, 90(11): 1338-44.</mixed-citation><mixed-citation xml:lang="en">Ginzburg E, Cohn SM, Lopez J, Jackowski J, Brown M, Hameed SM et al. Randomized clinical trial of intermittent pneumatic compression and low molecular weight heparin in trauma. Br J Surg, 2003, 90(11): 1338-44.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Akl EA, Karmath G, Yosuico V, Kim SY, Barba M, Sperati F, Cook D, Schünemann HJ. Anticoagulation for thrombosis prophylaxis in cancer patients with central venous catheters. Cochrane Database of Systematic Reviews: Reviews 2007 Issue 3 John Wiley &amp; Sons, Ltd Chichester, UK DOI: 10.1002/14651858.CD006468.pub2 2007.</mixed-citation><mixed-citation xml:lang="en">Akl EA, Karmath G, Yosuico V, Kim SY, Barba M, Sperati F, Cook D, Schünemann HJ. Anticoagulation for thrombosis prophylaxis in cancer patients with central venous catheters. Cochrane Database of Systematic Reviews: Reviews 2007 Issue 3 John Wiley &amp; Sons, Ltd Chichester, UK DOI: 10.1002/14651858.CD006468.pub2 2007.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
