medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2017-10-18-24medsovet-1862Research ArticleКОГНИТИВНЫЕ НАРУШЕНИЯ И ДЕМЕНЦИЯCOGNITIVE IMPAIRMENT AND DEMENTIAБОЛЕЗНЬ АЛЬЦГЕЙМЕРА: НОВЫЕ КРИТЕРИИ ДИАГНОСТИКИ И ТЕРАПЕВТИЧЕСКИЕ АСПЕКТЫ В ЗАВИСИМОСТИ ОТ СТАДИИ БОЛЕЗНИALZHEIMER’S DISEASE: NEW DIAGNOSTIC CRITERIA AND THERAPEUTIC ASPECTS DEPENDING ON THE STAGE OF THE DISEASEКоберскаяН. Н.KoberskayaN. N.

Кандидат медицинских наук

Первый Московский государственный университет им. И.М. Сеченова Минздрава РоссииРоссияSechenov First Moscow State University of the Ministry of Health of RussiaRussian Federation2017240520170101824Copyright © Коберская Н.Н., 20172017Коберская Н.Н.Koberskaya N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/1862

Обсуждаются новые критерии диагностики болезни Альцгеймера (БА), предложенные Национальным институтом старения США и Альцгеймеровской ассоциацией. Введено определение доклинической и преддементной стадий БА. Рассматриваются вопросы современной диагностики патофизиологического процесса при БА с использованием биологических маркеров и современных методов нейровизуализации, подходы к лечению  БА в зависимости от стадии болезни. Отмечается эффективность мемантина (Акатинола мемантина) и целесообразность его использования на разных стадиях заболевания у пациентов с БА. Рассматриваются немедикаментозные методы терапии БА, включая когнитивный  тренинг, поведенческие и психосоциальные методы.

The new criteria for diagnosing Alzheimer’s disease (AD) proposed by the United States National Aging Institute and the Alzheimer Association are being discussed. The definition of the preclinical and pre-dementing stages of AD has been introduced. The current issues of diagnostics of the pathophysiological process in AD with the use of biological markers and modern neurovisualization methods, approaches to treatment of AD depending on the stage  of the disease  are considered. The effectiveness  of Memantine  (akatynol  memantine)  and  its  usefulness   at  the  various  stages   of  disease   in  patients  with  AD is  noted. Nonpharmacological methods of AD therapy, including cognitive training, behavioural and psychosocial methods, are considered.

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The authors declare that there are no conflicts of interest present.