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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-6-84-86</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1890</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Химиотерапия злокачественных опухолей</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Malignant tumor chemotherapy</subject></subj-group></article-categories><title-group><article-title>ТЕЙСУНО В ПЕРВОЙ ЛИНИИ ТЕРАПИИ ДИССЕМИНИРОВАННОГО РАКА ЖЕЛУДКА</article-title><trans-title-group xml:lang="en"><trans-title>TEYSUNO: FIRST-LINE CHEMOTHERAPY FOR PATIENTS WITH DISSEMINATED GASTRIC CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ГОРДЕЕВА</surname><given-names>О. О.</given-names></name><name name-style="western" xml:lang="en"><surname>GORDEEVA</surname><given-names>O. O.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>АБРАМОВ</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>ABRAMOV</surname><given-names>M. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЛУД</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>LUD</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский онкологический научный центр им. Н.Н. Блохина Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>06</month><year>2017</year></pub-date><volume>0</volume><issue>6</issue><fpage>84</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; ГОРДЕЕВА О.О., АБРАМОВ М.Е., ЛУД А.Н., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">ГОРДЕЕВА О.О., АБРАМОВ М.Е., ЛУД А.Н.</copyright-holder><copyright-holder xml:lang="en">GORDEEVA O.O., ABRAMOV M.E., LUD A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1890">https://www.med-sovet.pro/jour/article/view/1890</self-uri><abstract><p>Рак желудка – одна из лидирующих причин смерти среди злокачественных образований в России. Имеющиеся на данный момент терапевтические подходы не приводят к значимому увеличению безрецидивной и общей выживаемости. На данный момент существует необходимость в поиске новых препаратов для лечения пациентов с этим заболеванием. Препарат Тейсуно (тегафур/гимерацил/отерацил, ТГО) продемонстрировал свою эффективность в первой линии лечения пациентов с диссеминированным раком желудка и некоторых других злокачественных новообразований. Препарат был зарегистрирован в Японии, США, Европе, а также в Российской Федерации. Внедрение в клиническую практику большего количества химиотерапевтических агентов расширяет терапевтические возможности для этой группы пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Gastric cancer is one of the leading causes of death among all cancers in Russia. Progression-free and overall survival cannot be drastically changed by current therapeutic approaches. There is a strong need in new drugs for that disease. Teysuno has demonstrated its efficacy in treatment of advanced gastric cancer and some other cancers. The more drugs we obtain for clinical practice the more opportunities we can offer for these patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>Тейсуно</kwd><kwd>фторпиримидины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastric cancer</kwd><kwd>Teysuno</kwd><kwd>fluoropyrimidines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2015 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2017.</mixed-citation><mixed-citation xml:lang="en">Злокачественные новообразования в России в 2015 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. 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