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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-11-202-207</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1943</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTANT</subject></subj-group></article-categories><title-group><article-title>ИСТОРИЯ РОЖДЕНИЯ СТАТИНОВ НОВЫЕ ПЕРСПЕКТИВЫ</article-title><trans-title-group xml:lang="en"><trans-title>HISTORY OF STATINS DEVELOPMENT. NEW PROSPECTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дреева</surname><given-names>З. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dreeva</surname><given-names>Z. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Postgraduate.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агеев</surname><given-names>Ф. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ageev</surname><given-names>F. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор.</p><p>Москва</p></bio><bio xml:lang="en"><p>MD, Prof.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-исследовательский институт клинической кардиологии им. А.Л. Мясникова Российского кардиологического  научнопроизводственного  комплекса Минздрава России<country>Россия</country></aff><aff xml:lang="en">Myasnikov Scientific and Research Institute of Clinical Cardiology of the Russian Cardiologic Scientific and Production Complex of the Ministry of Health of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>04</day><month>07</month><year>2017</year></pub-date><volume>0</volume><issue>11</issue><fpage>202</fpage><lpage>207</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дреева З.В., Агеев Ф.Т., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Дреева З.В., Агеев Ф.Т.</copyright-holder><copyright-holder xml:lang="en">Dreeva Z.V., Ageev F.T.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1943">https://www.med-sovet.pro/jour/article/view/1943</self-uri><abstract><p>Статины  используются  со второй  половины XX века. Прошло   достаточно времени, чтобы понять истинное значение роли статинов в лечении сердечно-сосудистых заболеваний. Большой вклад в этом напправлении вносит новая область в изучении статинов – сердечная  недостаточность с сохранной фракцией выброса.</p></abstract><trans-abstract xml:lang="en"><p>Statins have been used since the second half of the XXth century. It’s been a while time to understand the importance of statins in the treatment of cardiovascular disorders.Statins therapy in HFPEF is a new area that contributes significantly to the treatment of heart disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>статины</kwd><kwd>ингибиторы ГМГ-КоА-редуктазы</kwd><kwd>диастолическая функция левого желудочка</kwd><kwd>сердечная недостаточность с сохранной фракцией выброса</kwd></kwd-group><kwd-group xml:lang="en"><kwd>statins</kwd><kwd>inhibitors of HMG-COA reductase diastolic function of the left ventricle</kwd><kwd>heart failure with preserved ejection fraction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Steinberg D. Chemotherapeutic approaches to the problem of hyperlipidemia. Adv Pharmacol, 1962, 1: 59-159.</mixed-citation><mixed-citation xml:lang="en">Steinberg D. 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