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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-9-14-20</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1945</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕОНАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEONATOLOGY</subject></subj-group></article-categories><title-group><article-title>ХАРАКТЕРИСТИКА ФИЗИЧЕСКОГО И ПСИХОМОТОРНОГО РАЗВИТИЯ ДЕТЕЙ, РОЖДЕННЫХ ОТ МАТЕРЕЙ С ГЕСТАЦИОННЫМ САХАРНЫМ ДИАБЕТОМ</article-title><trans-title-group xml:lang="en"><trans-title>CHARACTERIZATION OF PSYCHOLOGICAL AND PHYSICAL DEVELOPMENT IN CHILDREN OF GESTATION DIABETES PREGNANCIES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>НИКИТИНА</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>NIKITINA</surname><given-names>I. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КОНОПЛЯ</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>KONOPLYA</surname><given-names>I. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ПОЛЯНСКАЯ</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>POLYANSKAYA</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЛИСКИНА</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>LISKINA</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ПОПОВА</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>POPOVA</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>The North-West Federal Almazov Medical Research Centre</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный федеральный медицинский исследовательский центр им. В.А. Алмазова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The North-West Federal Almazov Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2017</year></pub-date><volume>0</volume><issue>9</issue><fpage>14</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; НИКИТИНА И.Л., КОНОПЛЯ И.С., ПОЛЯНСКАЯ А.А., ЛИСКИНА А.С., ПОПОВА П.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">НИКИТИНА И.Л., КОНОПЛЯ И.С., ПОЛЯНСКАЯ А.А., ЛИСКИНА А.С., ПОПОВА П.В.</copyright-holder><copyright-holder xml:lang="en">NIKITINA I.L., KONOPLYA I.S., POLYANSKAYA A.A., LISKINA A.S., POPOVA P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1945">https://www.med-sovet.pro/jour/article/view/1945</self-uri><abstract><p>Физическое и нервно-психическое развитие детей, рожденных от матерей с гестационным сахарным диабетом (ГСД), представляет исследовательский интерес. Мы обследовали 28 детей, у матерей которых был диагностирован ГСД, в периоде новорожденности и в 6 месяцев. По параметрам физического развития при рождении преобладали дети с опереже-нием роста и средними значениями индекса массы тела (ИМТ), а к концу первого полугодия жизни большинство детей имели значения названных параметров в среднем, т. е. нормальном для данного возраста, диапазоне, однако удельный вес дефицитного ИМТ оставался неизменным. Инсулинотерапия во время беременности не оказывала значимого влияния на частотные характеристики детей с отклонениями в физическом развитии. Отклонения в нервно-психическом развитии детей 6-месячного возраста, рожденных от женщин с гестационным сахарным диабетом и нецелевым метаболическим контролем, в большей степени были представлены нарушениями сенсорной сферы и взаимодействия с предметами; в меньшей степени – развитием эмоциональной и голосовой сфер. Наименьшие отклонения у детей данной группы были установлены в отношении развития двигательной сферы</p></abstract><trans-abstract xml:lang="en"><p>The physical and neurological development of children born to mothers with gestation diabetes mellitus (GDM) is a matter of research interest. We examined 28 children whose mothers were diagnosed with GDM, in the newborn period and at 6 months. By the parameters of physical development at birth the number of children with outstripping development and the average body mass index (BMI) was predominant and by the end of the first semester of life most of the children had the values of the average parameters specified above, that is, normal for that age, range, but the proportion of the deficient BMI remained unchanged. Insulin therapy during pregnancy had no significant impact on the frequency characteristics of children with physical development disorders. The neurological disorders of the six-month-old children born of women with gestation diabetes mellitus and non-targeted metabolic control were more severely represented by sensory sphere disturbances and interaction with subjects; to a lesser extent - by emotional and voice development. The children of this group had the minimum disturbances in the development of the motor sphere.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гестационный сахарный диабет</kwd><kwd>дети</kwd><kwd>физическое развитие</kwd><kwd>нервно-психическое развитие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Gestation diabetes mellitus</kwd><kwd>children</kwd><kwd>physical development</kwd><kwd>neurological development</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Краснопольский В.И., Сухих Г.Т. Проект Российского консенсуса «Гестационный сахарный диабет: диагностика, лечение, послеродовое наблюдение». Сахарный диабет, 2012, 2: 6-12.</mixed-citation><mixed-citation xml:lang="en">Metzger EB, Lowe LP, Dyer AR, Trimble ER, Rajavithi ChU, Coustan DR et al. Hyperglycemia and adverse pregnancy outcome. New Eng J Med, 2008, 358(19): 1991-2002.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ультразвуковая фетометрия (справочные таблицы и номограммы). Под ред. М.В. Медведева. М.: Реал Тайм, 2006.</mixed-citation><mixed-citation xml:lang="en">Coustan DR, Lowe LP, Dyer AR, Metzeger BE. The HAPO Study: Paving The Way For New Diagnostic Criteria For GDM. Am J Obstet Gynecol, 2010, 202(6): 654.e1-654.e6.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Михно В.А., Никитина И.Л. Дисфункция эндотелия как фактор риска сахарного диабета и сердечно-сосудистой патологии. Забайкальский медицинский вестник, 2009, 1: 53-64.</mixed-citation><mixed-citation xml:lang="en">Schaefer-Graf UM, Wendt L, Sacks DA, KilavuzÖ, Gaber B, Metzner S, Vetter K, Abou-Dakn M How many sonograms are needed to reliably predict the absence of fetal overgrowth in gestational diabetes mellitus pregnancies? Diabetes Care, 2011, 34(1): 39-43.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Баженова О.В. Диагностика психического развития детей первого года жизни. М.: Издательство МГУ, 1986. 85 с.</mixed-citation><mixed-citation xml:lang="en">Buchanan TA, Kjos SL, Schafer U, Peters RK, Xiang A, Byrne J et al. Utility of foetal measurements in the management of gestational diabetes mellitus. Diabetes Care, 1998, 21(Suppl 2): B99-106.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Никитина И.Л. Особенности йоддефицитных заболеваний у детей Забайкальского региона. Автореф. дис… д-ра мед. наук. М., 2002. 48 с.</mixed-citation><mixed-citation xml:lang="en">Krishnaveni GV, Hill JC, Leary SD, Veena SR, Saperia J, Saroja A et al. Anthropometry, glucose tolerance and insulin concentrations in Indian children: relationships to maternal glucose and insulin concentrations during pregnancy. Diabetes Care, 2005, 28: 2919-2925.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Примак Т.Д., Долгих В.В. Реабилитация нервно-психической активности детей раннего возраста при острых инфекционных заболеваниях. Новосибирск: Наука, 2004. 86 с.</mixed-citation><mixed-citation xml:lang="en">Thaware PK, McKenna S, Patterson SS, Hadden DR, Pettitt DJ, McCance DR. Unrelated mild hyperglycemia during pregnancy and anthropometric measures of obesity in offspring at age 5-7 years. Diabetes Care, 2015, 38: 1701-1706.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Crume TL, Ogden L, Daniels S, Hamman RF, Norris JM, Dabelea D. The impact of in utero exposure to diabetes on childhood body mass index growth trajectories: the EPOCH study. J Pediatr, 2011, 158: 941-946.</mixed-citation><mixed-citation xml:lang="en">Crume TL, Ogden L, Daniels S, Hamman RF, Norris JM, Dabelea D. The impact of in utero exposure to diabetes on childhood body mass index growth trajectories: the EPOCH study. J Pediatr, 2011, 158: 941-946.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Dabelea D, Crume TL. Maternal environment and the transgenerational cycle of obesity and diabetes. Diabetes, 2011, 60: 1849-1855.</mixed-citation><mixed-citation xml:lang="en">Dabelea D, Crume TL. Maternal environment and the transgenerational cycle of obesity and diabetes. Diabetes, 2011, 60: 1849-1855.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Bozkurt L, Göbl CS, Rami-Merhar B, Winhofer Y, Baumgartner-Parzer S, Schober E, Kautzky-Willer A. The Cross-Link between Adipokines, Insulin Resistance and Obesity in Offspring of Diabetic Pregnancies. Horm Res Paediatr, 2016, 86: 300-308.</mixed-citation><mixed-citation xml:lang="en">Bozkurt L, Göbl CS, Rami-Merhar B, Winhofer Y, Baumgartner-Parzer S, Schober E, Kautzky-Willer A. The Cross-Link between Adipokines, Insulin Resistance and Obesity in Offspring of Diabetic Pregnancies. Horm Res Paediatr, 2016, 86: 300-308.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
