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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-13-50-53</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-1985</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Контрацепция</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Contraception</subject></subj-group></article-categories><title-group><article-title>ПРЕДМЕНСТРУАЛЬНЫЙ СИНДРОМ. НОВЫЕ ВОЗМОЖНОСТИ ТЕРАПИИ</article-title><trans-title-group xml:lang="en"><trans-title>PREMENSTRUAL SYNDROME NEW POSSIBILITIES OF THERAPY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лисицына</surname><given-names>О И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lisitsyna</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хилькевич</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Khilkevich</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н.,</p><p>Москва</p></bio><bio xml:lang="en"><p>MD., </p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. акад. В.И. Кулакова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>08</day><month>10</month><year>2017</year></pub-date><volume>0</volume><issue>13</issue><fpage>50</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лисицына О.И., Хилькевич Е.Г., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Лисицына О.И., Хилькевич Е.Г.</copyright-holder><copyright-holder xml:lang="en">Lisitsyna O.I., Khilkevich E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/1985">https://www.med-sovet.pro/jour/article/view/1985</self-uri><abstract><p>Предменструальный синдром (ПМС)  – сложный патологический симптомокомплекс, проявляющийся различными нейропсихическими, вегетативно-сосудистыми и обменно-эндокринными нарушениями, который влияет на качество жизни пациенток и снижает их работоспособность.</p><p>Лечение ПМС начинают с подбора диеты, коррекции режима труда и отдыха, максимального снижения психоэмоциональных нагрузок. С целью медикаментозного воздействия используют гормональную терапию, психотропные препараты, нестероидные противовоспалительные препараты, мочегонные, растительные и гомеопатические препараты, витаминотерапию. Наиболее патогенетически обоснованной является гормональная терапия.</p><p>Использование комбинированных оральных контрацептивов, обогащенных фолатами, в качестве терапии ПМС оказывает дополнительное эффективное воздействие на нервную систему, способствует стабилизации центральных нейрорегуляторных механизмов, а также снижению выраженности эмоционально-аффективных симптомов и когнитивных нарушений. </p></abstract><trans-abstract xml:lang="en"><p>The premenstrual syndrome (PMS) is a complex pathological symptom manifesting itselft through variety of neuropsychiatric, vegetative-vascular and metabolic-endocrine disorders that affect the quality of life of patients and reduces their working ability.</p><p>The treatment of PMS starts with the selection of diets, correction of the working and rest periods and the maximum reduction of psychoemotional stress. For the purpose of pharmaceutical effetc hormonal therapies, psychotropic drugs, nonsteroid antiinflammatory drugs, diuretics, plant and homeopathic drugs, vitamins are used. The most pathogenetically reasonable is hormonal therapy.</p><p>The use of combined oral contraceptives enriched by folates as a way of PMS therapy has an additional effective impact on the nervous system, contributes to the stabilization of the central neuroregulatory mechanisms and reduces the expression of  emotional and affective symptoms and cognitive disorders.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>предменструальный синдром</kwd><kwd>синдром предменструального напряжения</kwd><kwd>комбинированные оральные контрацептивы</kwd><kwd>дроспиренон</kwd><kwd>фолиевая кислота</kwd><kwd>фолаты</kwd><kwd>метафолин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>The premenstrual syndrome (PMS) is a complex pathological symptom manifesting itselft through variety of neuropsychiatric</kwd><kwd>vegetative-vascular and metabolic-endocrine disorders that affect the quality of life of patients and reduces their working ability. The treatment of PMS starts with the selection of diets</kwd><kwd>correction of the working and rest periods and the maximum reduction of psychoemotional stress. For the purpose of pharmaceutical effetc hormonal therapies</kwd><kwd>psychotropic drugs</kwd><kwd>nonsteroid antiinflammatory drugs</kwd><kwd>diuretics</kwd><kwd>plant and homeopathic drugs</kwd><kwd>vitamins are used. The most pathogenetically reasonable is hormonal therapy. The use of combined oral contraceptives enriched by folates as a way of PMS therapy has an additional effective impact on the nervous system</kwd><kwd>contributes to the stabilization of the central neuroregulatory mechanisms and reduces the expression of  emotional and affective symptoms and cognitive disorders. 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