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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-12-26-32</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2006</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АРТЕРИАЛЬНАЯ ГИПЕРТЕНЗИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTERIAL HYPERTENSION</subject></subj-group></article-categories><title-group><article-title>ЛЕЧЕНИЕ АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИИ И ПРОФИЛАКТИКА СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ У ЖЕНЩИНЫ РЕПРОДУКТИВНОГО ВОЗРАСТА С МИГРЕНЬЮ</article-title><trans-title-group xml:lang="en"><trans-title>THERAPY OF ARTERIAL HYPERTENSION AND PREVENTION OF CARDIOVASCULAR DISEASES IN WOMAN OF REPRODUCTIVE AGE SUFFERING FROM MIGRAINE. CLINICAL REVIEW</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кисляк</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kislyak</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стародубова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Starodubova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Червякова</surname><given-names>Ю. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Chervyakova</surname><given-names>Y. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России;&#13;
Федеральный исследовательский центр питания, биотехнологии и безопасности пищи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University of the Ministry of Health of Russia;&#13;
Federal Research Center of Nutrition, Biotechnology and Food Safety</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>02</day><month>11</month><year>2017</year></pub-date><volume>0</volume><issue>12</issue><fpage>26</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кисляк О.А., Стародубова А.В., Червякова Ю.Б., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Кисляк О.А., Стародубова А.В., Червякова Ю.Б.</copyright-holder><copyright-holder xml:lang="en">Kislyak O.A., Starodubova A.V., Chervyakova Y.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2006">https://www.med-sovet.pro/jour/article/view/2006</self-uri><abstract><p>Разбирается клинический случай артериальной гипертензии в сочетании с мигренью у женщины репродуктивного возраста. Обсуждается тактика антигипертензивной терапии с позиций лечения артериальной гипертензии и профилактики сердечно-сосудистых заболеваний и предотвращения приступов мигрени. Проводится анализ существующих рекомендаций по профилактике кардиоваскулярных и цереброваскулярных заболеваний у женщин и предлагается алгоритм медикаментозной терапии, основанный на имеющихся данных об общности патофизиологических механизмов развития артериальной гипертензии и мигрени и результатах клинических исследований.</p><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>A clinical case of the arterial hypertension in combination with migraine is considered in a woman of a reproductive age. The tactics of the antihypertensive therapy is discussed from the point of view of therapy of arterial hypertension and prevention of cardiovascular diseases and prevention of migraine attacks. Existing recommendations on prevention of cardiovascular and cerebrovascular diseases in women are analyzed and an algorithm of the drug therapy based on the available data about the general nature of pathophysiological mechanism of development of arterial hypertension and migraine is provided. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>мигрень</kwd><kwd>молодой возраст</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>блокаторы рецепторов ангиотензина</kwd><kwd>кандесартан</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>migraine</kwd><kwd>young age</kwd><kwd>cardiovascular disease</kwd><kwd>angiotensin blocking receptors</kwd><kwd>Candesartan</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cardiovascular disease in Europe: epidemiological update 2016. European Heart Journal, 2016, 0: 1–14. doi:10.1093/eurheartj/ehw334.</mixed-citation><mixed-citation xml:lang="en">Cardiovascular disease in Europe: epidemiological update 2016. European Heart Journal, 2016, 0: 1–14. doi:10.1093/eurheartj/ehw334.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Effectiveness-based guidelines for the prevention of cardiovascular disease in women – 2011 update: a guideline from the Аmerican Heart Association. Circulation, 2011, 123: 1243–62.</mixed-citation><mixed-citation xml:lang="en">Effectiveness-based guidelines for the prevention of cardiovascular disease in women – 2011 update: a guideline from the Аmerican Heart Association. Circulation, 2011, 123: 1243–62.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Towfighi, A, Zheng, L, Ovbiagele, B. Sex-specific trends in midlife coronary heart disease risk and prevalence. Arch Intern Med, 200, 169: 1762-1766.</mixed-citation><mixed-citation xml:lang="en">Towfighi, A, Zheng, L, Ovbiagele, B. Sex-specific trends in midlife coronary heart disease risk and prevalence. Arch Intern Med, 200, 169: 1762-1766.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">George J, Rapsomaniki E, Pujades-Rodriguez M, Shah AD, Denaxas S, Herrett E, Smeeth L, Timmis A, Hemingway H. How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1 937 360 People. Circulation, 2015, 132: 1320-1328. DOI: 10.1161/CIRCULATIONAHA.114.013797.</mixed-citation><mixed-citation xml:lang="en">George J, Rapsomaniki E, Pujades-Rodriguez M, Shah AD, Denaxas S, Herrett E, Smeeth L, Timmis A, Hemingway H. How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1 937 360 People. Circulation, 2015, 132: 1320-1328. DOI: 10.1161/CIRCULATIONAHA.114.013797.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines for the Prevention of Stroke in Women A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke, 2014, 45: 1545-1588. DOI: 10.1161/01. str.0000442009.06663.48.</mixed-citation><mixed-citation xml:lang="en">Guidelines for the Prevention of Stroke in Women A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke, 2014, 45: 1545-1588. DOI: 10.1161/01. str.0000442009.06663.48.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">O’Donnell MJ, Xavier D, Liu L, Zhang H, Chin SL, Rao-Melacini P, Rangarajan S, Islam S, Pais P, McQueen MJ, Mondo C, Damasceno A, Lopez-Jaramillo P, Hankey GJ, Dans AL, Yusoff K, Truelsen T, Diener HC, Sacco RL, Ryglewicz D, Czlonkowska A, Weimar C, Wang X, Yusuf S, INTERSTROKE Investigators. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet, 2010, 376: 112–123.</mixed-citation><mixed-citation xml:lang="en">O’Donnell MJ, Xavier D, Liu L, Zhang H, Chin SL, Rao-Melacini P, Rangarajan S, Islam S, Pais P, McQueen MJ, Mondo C, Damasceno A, Lopez-Jaramillo P, Hankey GJ, Dans AL, Yusoff K, Truelsen T, Diener HC, Sacco RL, Ryglewicz D, Czlonkowska A, Weimar C, Wang X, Yusuf S, INTERSTROKE Investigators. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet, 2010, 376: 112–123.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">National Center for Health Statistics. Health, United States, 2011. Hyattsville, MD: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2012. http: //www.cdc.gov/nchs/hus/contents2011. htm#031. Accessed December 31, 2012.</mixed-citation><mixed-citation xml:lang="en">National Center for Health Statistics. Health, United States, 2011. Hyattsville, MD: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2012. http: //www.cdc.gov/nchs/hus/contents2011. htm#031. Accessed December 31, 2012.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Kannel WB, Wolf PA. The lifetime risk of stroke: estimates from the Framingham Study. Stroke, 2006, 37: 345–350.</mixed-citation><mixed-citation xml:lang="en">Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Kannel WB, Wolf PA. The lifetime risk of stroke: estimates from the Framingham Study. Stroke, 2006, 37: 345–350.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Подзолков В.И., Брагина А.Е. Комбинированная терапия артериальной гипертензии: фокус на лечение женщин. Лечебное дело, 2013, 2: 31-38.</mixed-citation><mixed-citation xml:lang="en">Подзолков В.И., Брагина А.Е. Комбинированная терапия артериальной гипертензии: фокус на лечение женщин. Лечебное дело, 2013, 2: 31-38.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Табеева Г.Р., Муранова А.В., Кострыгина Е.Н., Сергеев А.В. Мигрень и артериальная гшпертензия. Неврология, нейропсихиатрия, психосоматика, 2015, 7(4): 4–10.</mixed-citation><mixed-citation xml:lang="en">Табеева Г.Р., Муранова А.В., Кострыгина Е.Н., Сергеев А.В. Мигрень и артериальная гшпертензия. Неврология, нейропсихиатрия, психосоматика, 2015, 7(4): 4–10.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kurth T, Diener HC. Current views of the risk of stroke for migraine with and migraine without aura. Curr Pain Headache Rep, 2006, 10(3): 214-20.</mixed-citation><mixed-citation xml:lang="en">Kurth T, Diener HC. Current views of the risk of stroke for migraine with and migraine without aura. Curr Pain Headache Rep, 2006, 10(3): 214-20.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">12. Boubacar S, Assadeck H, Diallo IM, Cisse O, Ntenga P, Adji DB, Diagne NS, Maiga DD, Adehossi EO, Maiga Y, Toure K, Ndiaye M, Diop AG, Ndiaye MM. Migraine in women: what specificities? A review. J Womens Health Care, 2017, 6: 1, doi: 10: 4172/2167-0420.1000349.</mixed-citation><mixed-citation xml:lang="en">12. Boubacar S, Assadeck H, Diallo IM, Cisse O, Ntenga P, Adji DB, Diagne NS, Maiga DD, Adehossi EO, Maiga Y, Toure K, Ndiaye M, Diop AG, Ndiaye MM. Migraine in women: what specificities? A review. J Womens Health Care, 2017, 6: 1, doi: 10: 4172/2167-0420.1000349.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">2013 ESH/ESC Guidelines for the management of arterial hypertension. TheTask Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Journal of Hypertension, 2013, 31: 1281–1357.</mixed-citation><mixed-citation xml:lang="en">2013 ESH/ESC Guidelines for the management of arterial hypertension. TheTask Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Journal of Hypertension, 2013, 31: 1281–1357.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Российское медицинское общество по артериальной гипертонии (РМОАГ), Всероссийское научное общество кардиологов (ВНОК). Диагностика и лечение артериальной гипертензии. Российские рекомендации (четвертый пересмотр). Системные гипертензии, 2010, 3: 5–26.</mixed-citation><mixed-citation xml:lang="en">Российское медицинское общество по артериальной гипертонии (РМОАГ), Всероссийское научное общество кардиологов (ВНОК). Диагностика и лечение артериальной гипертензии. Российские рекомендации (четвертый пересмотр). Системные гипертензии, 2010, 3: 5–26.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Keto J, Ventola H, Jokelainen J, Linden К, Keinänen-Kiukaanniemi S, Timonen М Ylisaukko-oja Т, Auvinen J. Cardiovascular disease risk factors in relation to smoking behaviour and history: a population-based cohort study. Open Heart, 2016, 3: e000358. doi: 10.1136/openhrt-2015-000358.</mixed-citation><mixed-citation xml:lang="en">Keto J, Ventola H, Jokelainen J, Linden К, Keinänen-Kiukaanniemi S, Timonen М Ylisaukko-oja Т, Auvinen J. Cardiovascular disease risk factors in relation to smoking behaviour and history: a population-based cohort study. Open Heart, 2016, 3: e000358. doi: 10.1136/openhrt-2015-000358.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">The International Classification of Headache Disorders, 3rd edition (beta version). Headache Classification Committee of the International Headache Society (IHS). Cephalalgia, 2013, 33(9): 629–808. International Headache Society 2013 Reprints and permissions: sage-pub.co.uk/journals Permissions.nav DOI: 10.1177/0333102413485658.</mixed-citation><mixed-citation xml:lang="en">The International Classification of Headache Disorders, 3rd edition (beta version). Headache Classification Committee of the International Headache Society (IHS). Cephalalgia, 2013, 33(9): 629–808. International Headache Society 2013 Reprints and permissions: sage-pub.co.uk/journals Permissions.nav DOI: 10.1177/0333102413485658.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Hamed SA. Blood pressure changes in pftients with migraine: evidences, controversial views and potential mechanisms of comorbidity. J Neurology and Neuroscience, 2010, 2: 2. doi10: 3823/306.</mixed-citation><mixed-citation xml:lang="en">Hamed SA. Blood pressure changes in pftients with migraine: evidences, controversial views and potential mechanisms of comorbidity. J Neurology and Neuroscience, 2010, 2: 2. doi10: 3823/306.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Стародубова А.В., Драенкова О.В., Кисляк О.А., Копелев А.М., Косюра С.Д., Хаутиева Ф.М., Сергиенко В.И., Говорун В.М., Джеджея Л.В. Особенности жирового обмена у молодых женщин с избыточным и нормальным приростом массы тела во время беременности. Вестник Российского государственного медицинского университета, 2009, 2: 10-15.</mixed-citation><mixed-citation xml:lang="en">Стародубова А.В., Драенкова О.В., Кисляк О.А., Копелев А.М., Косюра С.Д., Хаутиева Ф.М., Сергиенко В.И., Говорун В.М., Джеджея Л.В. Особенности жирового обмена у молодых женщин с избыточным и нормальным приростом массы тела во время беременности. Вестник Российского государственного медицинского университета, 2009, 2: 10-15.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Nichols M, Townsend N, Luengo-Fernandez R, Leal J, Gray A, Scarborough P, Rayner M. European Cardiovascular Disease Statistics 2012. European Heart Network, Brussels, European Society of Cardiology, Sophia Antipolis, 2012. 122 р.</mixed-citation><mixed-citation xml:lang="en">Nichols M, Townsend N, Luengo-Fernandez R, Leal J, Gray A, Scarborough P, Rayner M. European Cardiovascular Disease Statistics 2012. European Heart Network, Brussels, European Society of Cardiology, Sophia Antipolis, 2012. 122 р.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Sachdec A, Marmura MJ. Metabolic syndrome and migraine. Frontiers in Neurology, 2012, 3: 8. Doi: 10/3389/fntur.2012.00161.</mixed-citation><mixed-citation xml:lang="en">Sachdec A, Marmura MJ. Metabolic syndrome and migraine. Frontiers in Neurology, 2012, 3: 8. Doi: 10/3389/fntur.2012.00161.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. Eur Heart J. 2016 Aug 27. pii: ehw272. [Epub ahead of print]. Eur Heart J, 2016, 37(39): 2999-3058.</mixed-citation><mixed-citation xml:lang="en">2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. Eur Heart J. 2016 Aug 27. pii: ehw272. [Epub ahead of print]. Eur Heart J, 2016, 37(39): 2999-3058.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Cushman WC, Goff DC. More HOPE for prevention with ststins. New Engl J Med, 2016, DOI: 10.1056/NEJMe1603504. Copyright © 2016 Massachusetts Medical Society.</mixed-citation><mixed-citation xml:lang="en">Cushman WC, Goff DC. More HOPE for prevention with ststins. New Engl J Med, 2016, DOI: 10.1056/NEJMe1603504. Copyright © 2016 Massachusetts Medical Society.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Bundy J D, Li С, Stuchlik P, Bu X, Kelly TN, Mills KT, He H, Chen J, Whelton PK, He J. Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality A Systematic Review and Network Meta-analysis. JAMA Cardiol. doi: 10.1001/jamacardio.2017.1421 Published online May 31, 2017.</mixed-citation><mixed-citation xml:lang="en">Bundy J D, Li С, Stuchlik P, Bu X, Kelly TN, Mills KT, He H, Chen J, Whelton PK, He J. Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality A Systematic Review and Network Meta-analysis. JAMA Cardiol. doi: 10.1001/jamacardio.2017.1421 Published online May 31, 2017.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Zheng Z, Shi H, Jia J, Li D, Lin S. A systematic review and meta-analysis of candesartan and losartan in the management of essential hypertension. Journal of the Renin-Angiotensin-Aldosterone System, 2011, Published online March 18, 1470320310391503.</mixed-citation><mixed-citation xml:lang="en">Zheng Z, Shi H, Jia J, Li D, Lin S. A systematic review and meta-analysis of candesartan and losartan in the management of essential hypertension. Journal of the Renin-Angiotensin-Aldosterone System, 2011, Published online March 18, 1470320310391503.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Tronvik E, Stovner LJ, Helde G, Sand T, Bovim G. Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial. JAMA, 2003, 289(1): 65-69.</mixed-citation><mixed-citation xml:lang="en">Tronvik E, Stovner LJ, Helde G, Sand T, Bovim G. Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial. JAMA, 2003, 289(1): 65-69.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Soliman S, Ishrat T, Pillai A, Somanath P R, Ergul A, El-Remessy AB, Fagan SC. Candesartan Induces a Prolonged Proangiogenic Effect and Augments Endothelium-Mediated Neuroprotection after Oxygen and Glucose Deprivation: Role of Vascular Endothelial Growth Factors A and B. J Pharmacol Exp Ther, 349: 444–457.</mixed-citation><mixed-citation xml:lang="en">Soliman S, Ishrat T, Pillai A, Somanath P R, Ergul A, El-Remessy AB, Fagan SC. Candesartan Induces a Prolonged Proangiogenic Effect and Augments Endothelium-Mediated Neuroprotection after Oxygen and Glucose Deprivation: Role of Vascular Endothelial Growth Factors A and B. J Pharmacol Exp Ther, 349: 444–457.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">The 2012 AHS/AAN Guidelines for Prevention of Episodic Migraine: A Summary and Comparison With Other Recent Clinical Practice Guidelines. Headache, 2012, 52: 930-945.</mixed-citation><mixed-citation xml:lang="en">The 2012 AHS/AAN Guidelines for Prevention of Episodic Migraine: A Summary and Comparison With Other Recent Clinical Practice Guidelines. Headache, 2012, 52: 930-945.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
