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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-12-100-104</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2017</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Дислипидемия</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Dyslipidemia</subject></subj-group></article-categories><title-group><article-title>РОЛЬ МОЩНЫХ СТАТИНОВ В СОВРЕМЕННОМ ЛЕЧЕНИИ БОЛЬНЫХ С ВЫСОКИМ РИСКОМ РАЗВИТИЯ ОСЛОЖНЕНИЙ, ОБУСЛОВЛЕННЫХ АТЕРОСКЛЕРОЗОМ</article-title><trans-title-group xml:lang="en"><trans-title>ROLE OF POWERFUL STATINS IN MODERN TREATMENT OF PATIENTS WITH A HIGH RISK OF COMPLICATIONS ARISING FROM ATHEROSCLEROSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гиляревский</surname><given-names>С. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Gilyarevskijy</surname><given-names>S. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голшмид</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Golshmid</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмина</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzmina</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования;&#13;
Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuing Vocational Education;&#13;
Sklifosovsky Emergency Research Institute of Emergency Medicine of the Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuing Vocational Education;</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sklifosovsky Emergency Research Institute of Emergency Medicine of the Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>11</month><year>2017</year></pub-date><volume>0</volume><issue>12</issue><fpage>100</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гиляревский С.Р., Голшмид М.В., Кузьмина И.М., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Гиляревский С.Р., Голшмид М.В., Кузьмина И.М.</copyright-holder><copyright-holder xml:lang="en">Gilyarevskijy S.R., Golshmid M.V., Kuzmina I.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2017">https://www.med-sovet.pro/jour/article/view/2017</self-uri><abstract><p>В статье рассматриваются современные подходы к лечению больных с атеросклерозом, приводятся данные об эффективности применения новых классов гиполипидемических препаратов, а также обсуждается роль интенсивных режимов применения статинов на современном этапе гиполипидемической терапии. Приводятся доказательные данные об эффективности применения розувастатина для снижения концентрации холестерина липопротеинов низкой плотности в крови и снижения риска развития осложнений сердечно-сосудистых заболеваний, обусловленных атеросклерозом.</p><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>The article discusses modern approaches to the treatment of atherogenic patients, provides data on the effectiveness of new hypolipidemic drugs and discusses the role of intensive statin use regimes at the modern stage of the lipid-lowering therapy. Evidence is provided on the effectiveness of the use of rosuvastatin to reduce blodo LDL-cholesterol and to reduce the risk of cardiovascular disease complications caused by atherosclerosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гиполипидемическая терапия</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>обусловленные атеросклерозом</kwd><kwd>эзетимиб</kwd><kwd>ингибиторы PCSK9</kwd><kwd>статины</kwd><kwd>розувастатин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypolipidemic therapy</kwd><kwd>cardiovascular diseases caused by atherosclerosis</kwd><kwd>ezetimibe</kwd><kwd>PCSK9 inhibitors</kwd><kwd>statins</kwd><kwd>rosuvastatin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Stone NJ, Robinson JG, Lichtenstein AH et al. 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