medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2017-12-112-117medsovet-2019Research ArticleСердечная недостаточностьHeart failureИННОВАЦИОННАЯ СТРАТЕГИЯ В ТЕРАПИИ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИINNOVATIVE STRATEGY IN THERAPY OF CARDIAC INSUFFICIENCYДжаианиН. А.JaianiN. A.

д.м.н., профессор

 

MD, Prof.

Московский государственный медико-стоматологический университет им. А.И. Евдокимова Минздрава РоссииРоссияEvdokimov Moscow State Medical and Stomatologic University of the Ministry of Health of RussiaRussian Federation201703112017012112117Copyright © Джаиани Н.А., 20172017Джаиани Н.А.Jaiani N.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2019

Статья посвящена инновационному препарату для лечения хронической сердечной недостаточности – комбинации ингибитора неприлизина сакубитрила и антагониста рецепторов ангиотензина II первого типа валсартана (сакубитрил/ валсартан). Приведены результаты исследований, в которых сочетание сакубитрил/валсартан продемонстрировало эффективность у больных как с артериальной гипертензией, так и с сердечной недостаточностью. Показаны преимущества комбинации сакубитрил/валсартан по сравнению с другими препаратами, влияющими на компоненты ренин-ангиотензин-альдостероновой системы, с позиций безопасности и эффективности у больных с сердечной недостаточностью.

 

 

 

 

The article is devoted to the innovative drug to treat chronic cardiac insufficiency – a combination of sakubitril neprilysin inhibitor and first type angiotension II receptor antagonist valsartan (sacubitril/valsartan). Study results are provided in which a combination of sacubitril/valsartan demonstrated effectiveness in patients with arterial hypertension as well as with cardiac insufficiency. Advantages of a combination of sacubitril/valsartan as compared to other drugs affecting components of rennin-angiotension-aldosteron system from the point of view of safety and effectiveness in patients with cardiac insufficiency are demonstrated.

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The authors declare that there are no conflicts of interest present.