medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2017-18-70-76medsovet-2035Research ArticleИнфекции в пульмонологииInfections in pulmonologyСОВРЕМЕННАЯ АНТИБАКТЕРИАЛЬНАЯ ТЕРАПИЯ НОЗОКОМИАЛЬНОЙ ПНЕВМОНИИMODERN ANTIBACTERIAL THERAPY IN HOSPITAL-ACQUIRED PNEUMONIAБелобородовВ. Б.BeloborodovV. B.

д.м.н., профессор

MD, Prof.

СиникинВ. А.SinikinV. A.Российская медицинская академия непрерывного профессионального образования Минздрава РоссииРоссияRussian Medical Academy of Continuous Professional Education of the Ministry of Health of RussiaRussian Federation2017031120170187076Copyright © Белобородов В.Б., Синикин В.А., 20172017Белобородов В.Б., Синикин В.А.Beloborodov V.B., Sinikin V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2035

Нозокомиальная пневмония терминологически объединяет все виды пневмонии, которые возникают у госпитализированных пациентов: пневмонию у пациентов вне искусственной вентиляции легких (госпитальная пневмония, пневмония, связанная с оказанием медицинской помощи) и нозокомиальную пневмонию, связанную с проведением ИВЛ (НПивл), или вентилятор-ассоциированную пневмонию (ВАП). Существенным отличием нозокомиальной пневмонии от внебольничной является разнообразная этиологическая структура, что существенно усложняет выбор антибактериальных препаратов, на этапе эмпирической терапии возникает необходимость применения антибиотиков, активных в отношении внебольничной и нозокомиальной флоры. Роль карбапенемов, в частности дорипенема, в лечении нозокомиальной пневмонии является ведущей в связи с его высокой активностью в отношении резистентной флоры.

 

Hospital-acquired pneumonia terminologically unites all types of pneumonia that arise in hospitalized patients: pneumonia in patients beyond artificial lungs ventilation (hospital pneumonia, medical aid-associated pneumonia) and hospital acquired pneumonia related to ALV (HAalv) or ventilator-associated pneumonia (VAP). A considerable difference of the hospital-acquired pneumonia from the community-acquired one is a different etiologic structure, which considerably complicates the choice of antibacterial drugs, at the stage of empirical therapy a necessity arises to use antibiotics active against community and hospital flora. The role of carbapenems, doripenem in particular, in therapy of hospital-acquired pneumonia is leading due to its high activity against the resistant flora.

 

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The authors declare that there are no conflicts of interest present.