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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2017-12-202-208</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2055</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTANT</subject></subj-group></article-categories><title-group><article-title>ДИНАМИКА ДИАСТОЛИЧЕСКОЙ ФУНКЦИИ ЛЕВОГО ЖЕЛУДОЧКА У ПАЦИЕНТОВ С ФИБРИЛЛЯЦИЕЙ ПРЕДСЕРДИЙ ПРИ РАЗЛИЧНЫХ СПОСОБАХ ВОССТАНОВЛЕНИЯ СИНУСОВОГО РИТМА</article-title><trans-title-group xml:lang="en"><trans-title>THE DYNAMICS OF DIASTOLIC FUNCTION OF THE LEFT VENTRICLE AT PATIENTS WITH ATRIAL FIBRILLATION AT VARIOUS METHODS OF SINUS RHYTHM RECOVERY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громыко</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromyko</surname><given-names>T. Y.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сайганов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sayganov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор </p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Северо-Западный государственный медицинский университет им. И.И. Мечникова<country>Россия</country></aff><aff xml:lang="en">North-Western State Medical University named after I.I. Mechnikov<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>04</day><month>11</month><year>2017</year></pub-date><volume>0</volume><issue>12</issue><fpage>202</fpage><lpage>208</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Громыко Т.Ю., Сайганов С.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Громыко Т.Ю., Сайганов С.А.</copyright-holder><copyright-holder xml:lang="en">Gromyko T.Y., Sayganov S.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2055">https://www.med-sovet.pro/jour/article/view/2055</self-uri><abstract><sec><title>Цель</title><p>Цель: оценить динамику диастолической функции (ДФ) левого желудочка (ЛЖ) при различных вариантах восстановления синусового ритма (СР). Материалы и методы: обследовано 153 пациента с неклапанной формой ФП длительностью от 48 часов до 6 месяцев. Все пациенты делились на 3 группы. В 1-ю – включены 49 пациентов, у которых СР восстанавливался с помощью медикаментозной терапии; во 2-ю – 57 пациентов, у которых СР восстанавливался с помощью электроимпульсной терапии (ЭИТ); в 3-ю – 47 пациентов, которым проводилась радиочастотная изоляция легочных вен (РЧИ ЛВ). Всем пациентам проводилось ЭХО-кардиографическое исследование (ЭХО КГ) на момент ФП, а также на 1, 3, 15-е сутки и через 6 месяцев после восстановления СР с оценкой систолической и диастолической функции ЛЖ, толщины стенок миокарда, переднезаднего размера (ПЗР) левого предсердия (ЛП), объема ЛП, а также времени восстановления функции ЛП по скорости пика А трансмитрального потока (ТМП). Результаты: исходно и в течение всего периода наблюдения диастолическая дисфункция (ДД) ЛЖ оказалась более выражена в группе пациентов, которым проводилась РЧИ ЛВ: исходно пик Е ТМП был достоверно ниже, чем в других группах (р &lt; 0,05); Е’, характеризующий активный компонент диастолы, на фоне ФП и при наблюдении до 6 месяцев также был самым низким в данной группе (р &lt; 0,05); E/E’ на фоне ФП, в 1-е сутки и до 6 месяцев после восстановления СР – самым высоким оказался при РЧИ ЛВ (р &lt; 0,05). Причем в данной группе отмечалось наиболее выраженное снижение Е/Е’ при отсутствии рецидивов ФП в течение 6 месяцев. Во всех группах E’ при измерении на фоне ФП оказался выше, чем при оценке его после восстановления СР. Вместе с тем отношение E/E’ при измерении на фоне ФП в группах консервативной терапии и РЧИ ЛВ оказалось ниже, чем после восстановления СР, а в группе ЭИТ достоверно не менялось. Выводы: при оценке ДФ ЛЖ на фоне ФП и в динамике на СР вызывает сомнение достоверность таких показателей, как E’ и E/E’, что требует поиска новых маркеров, отражающих ДФ ЛЖ у пациентов с ФП.</p></sec><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To estimate the dynamics of diastolic function (DF) of the left ventricle (LV) at patients with atrial fibrillation ()AF at various methods of sinus rhythm (SR) recovery. Material and methods. We examined 153 patients with the nonvalvular AF lasting from 48 hours to 6 months. All patients were divided in 3 groups. In group 1 (49 patients) SR was restored medically, in the group 2 (57 patients) SR was restored by means of electrical cardioversion (ECV), in the group 3(47 patients) underwent radio-frequency isolation of pulmonary veins (RFI PV). Echocardiography was performed to all patients at the time of AF, and also on 1,5,15 days and in 6 months after recovery of SR with an assessment systolic and the diastolic function of left ventricle (LV), thickness of walls of a myocardium, the front and back size of the left atrial (LA), volume of LA, and also time of restoration of the LA function on a transmitral flow – peak A. Results. Initially and during the period of observation the diastolic dysfunction (DD) of LV has been severe in group of RFI PV: at time of AF the peak of E was below, than in other groups (р &lt; 0,05); Е’, the characterizing active component of a diastola, at time of AF and within 6 months after SR recovery also was the lowest in this group (р&lt;0,05); E/E’ at time of AF and up to 6 months after restoration of SR – the highest has turned out at group of RFI PV (р &lt; 0,05). And in this group the most expressed decrease of E/E’ was noted at patients without paroxysms of AF. In all groups E’ in the presence of AF was higher than after SR recovery. And also E/E’ was noted below at time of AF than after SR recovery at groups of medical restoration and RFI PV, and in group of ECV this parameter didn’t change. Conclusions: at patients with AF such parameters as E’ and E/E’ didn’t appeared true regarding DF LV, that demands search of the new markers DF LV at patients with AF.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>диастолическая функция левого желудочка</kwd><kwd>кардиоверсия</kwd><kwd>восстановление синусового ритма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>cardioversion</kwd><kwd>recovery of a sinus rhythm</kwd><kwd>diastolic function</kwd><kwd>left ventricle</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мишина Т.Е., Глухова Е.З. 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