medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2017-19-120-125medsovet-2200Research ArticleГАСТРОЭНТЕРОЛОГИЯGASTROENTEROLOGYЖЕЛТУХИ ЗДОРОВОГО НОВОРОЖДЕННОГО: ПРИЧИНЫ, ТЕЧЕНИЕ, ПРОГНОЗHEALTHY NEWBORN JAUNDICES: CAUSES, COURSE, PROGNOSISГоряйноваА. Н.GoryanovaA. N.

к.м.н.,

Москва

PhD in medicine

АнцуповаМ. А.AntsupovaM. A.

Москва

Moscow

ЗахароваИ. Н.ZakharovaI. N.

д.м.н., профессор,

Москва

Российская медицинская академия непрерывного медицинского образования Минздрава РоссииРоссияRussian Medical Academy of Continuous Postgraduate Education of the Ministry of Health of RussiaRussian FederationДетская городская клиническая больница им. З.А. БашляевойРоссияBashlyaeva Children Municipal Clinical HospitalRussian Federation201715122017019120125Copyright © Горяйнова А.Н., Анцупова М.А., Захарова И.Н., 20172017Горяйнова А.Н., Анцупова М.А., Захарова И.Н.Goryanova A.N., Antsupova M.A., Zakharova I.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2200

Желтуха у новорожденных является самым частым симптомом и в подавляющем большинстве случаев отражает особенности билирубинового обмена в неонатальном периоде. У здоровых новорожденных возможны два варианта желтух, не требующих лечения и обусловленных гипербилирубинемией: физиологическая и естественного вскармливания. В основе желтух здорового новорожденного лежит транзиторное нарушение билирубинового клиренса (конъюгации непрямого билирубина), не оказывающее влияние на развитие ребенка. Желтуха естественного вскармливания отличается пролонгированным, до 2–3 мес, течением, при этом физическое и психомоторное развитие ребенка не страдают. Тем не менее затяжное (более 14 дней жизни) течение желтухи требует определения уровня билирубина и его фракций в динамике для исключения более серьезных причин гипербилирубинемии.

Jaundice in newborns is the most common symptom and in the vast majority of cases reflects the characteristics of bilirubin metabolism in the neonatal period. In healthy newborns there are two kinds of jaundice that do not require treatment and are caused by hyperbilirubinemia: physiologic and breastfeeding ones. Transient disturbance of the bilirubin clearance (indirect bilirubin conjugation) not affecting the child development lies at the core of a healthy newborn jaundice. Jaundice of breastfeeding differs by prolonged course (up to 2-3 months) while physical and psychomotor development of the child is not affected. However prolonged course (over 14 days of life) of jaundice requires determination of bilirubin and its fractions in dynamics to rule out more serious causes of hyperbilirubinemia.

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The authors declare that there are no conflicts of interest present.