medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2017-19-162-167medsovet-2208Research ArticleНЕФРОЛОГИЯ / УРОЛОГИЯNEPHROLOGY / UROLOGYБЕССИМПТОМНАЯ БАКТЕРИУРИЯ: СМЕНА ОБЩЕПРИНЯТОГО ВЗГЛЯДАASYMPTOMATIC BACTERIURIA: CHANGE OF THE COMMON OPINIONЗахароваИ. Н.ZakharovaI. N.

д.м.н., профессор,

Москва

MD, Prof., 

Moscow

ОсмановИ. М.OsmanovI. M.

д.м.н., профессор,

Москва

MD, Prof.,

Moscow

МумладзеЭ. Б.MumladzeE. B.

к.м.н., 

Москва

PhD in medicine, 

Moscow

МачневаЕ. Б.MachnevaE. B.

к.м.н., 

Москва

PhD in medicine, 

Moscow

ТамбиеваЕ. В.TambievaE. V.

к.м.н.,

Москва

PhD in medicine, 

Moscow

БекмурзаеваГ Б.MekburzaevaG. B.

Москва

Moscow

Российская медицинская академия непрерывного последипломного образования Минздрава РоссииРоссияRussian Medical Academy of Continuous Postgraduate Education of the Ministry of Health of RussiaRussian FederationРоссийский научный исследовательский медицинский университет им. И.И. Пирогова Минздрава РоссииРоссияPirogov Russian Scientific and Research Medical University of the Ministry of Health of RussiaRussian FederationРоссийский научный исследовательский медицинский университет им. И.И. Пирогова Минздрава РоссииРоссияBashlyaeva Children Municipal Clinical Hospital of the Ministry of Health of MoscowRussian Federation201718122017019162167Copyright © Захарова И.Н., Османов И.М., Мумладзе Э.Б., Мачнева Е.Б., Тамбиева Е.В., Бекмурзаева Г.Б., 20172017Захарова И.Н., Османов И.М., Мумладзе Э.Б., Мачнева Е.Б., Тамбиева Е.В., Бекмурзаева Г.Б.Zakharova I.N., Osmanov I.M., Mumladze E.B., Machneva E.B., Tambieva E.V., Mekburzaeva G.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2208

За последние 50 лет неоднократно менялись подходы к диагностике и лечению бессимптомной бактериурии (ББУ). Ранее бактериурия рассматривалась как проявление скрытой патологии, которую необходимо выявлять и лечить антибактериальными препаратами. Однако по мере накопления и появления новых научных данных, совершенствования методов исследования стало понятно, что наличие ББУ у человека не только не вредит его здоровью, но, скорее, напротив, защищает его от развития инфекции мочевых путей (ИМП). В настоящее время многие исследователи вновь обратились к  изучению ББУ, получив уникальные данные, свидетельствующие о том, что понимание этой проблемы может помочь раскрыть ранее неизвестные патогенетические, иммунные и генные механизмы развития ИМП, в результате чего будут получены и принципиально новые возможности их эффективного лечения. Это представляется особенно важным в эру повсеместно возрастающей резистентности микроорганизмов к антибиотикам.

Over the last 50 years an approach to diagnosis and treatment of asymptomatic bacteriuria (BB) has changed. Previously bacteriuria was considered as a manifestation of an underlying pathology that must be identified and treated with antibiotics. However the accumulation and emergence of new scientific data to improve methods of research allowed understanding that the presence of BB in humans is not only harmful to health but rather on the contrary protects it from developing symptomatic urinary tract infection (UTI). Currently, many researchers turned to the study of BB, having unique data, showing that understanding this issue can help uncover previously unknown pathogenetic, immunological and genetic mechanisms of development of IMP, the result of which will be obtained and new opportunities for effective treatment. This is particularly important in the era of ubiquitous increasing microbial resistance to antibiotics.

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The authors declare that there are no conflicts of interest present.