medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2017-20-144-150medsovet-2245Research ArticleРЕВМАТОЛОГИЯRHEUMATOLOGYУРАТСНИЖАЮЩАЯ ТЕРАПИЯ ПОДАГРЫ: ОСНОВНЫЕ ПРИНЦИПЫ И РЕАЛЬНЫЕ ВОЗМОЖНОСТИPNEUMOCYSTIC PNEUMONIA IN RHEUMATIC DISEASES: CURRENT ISSUES IN PROPHYLAXISЕлисеевМ. С.EliseevM. S.

кандидат медицинских наук.

Москва. 

 PhD in medicine.

Moscow. 

Научно-исследовательский институт ревматологии им. В.А. Насоновой.РоссияNasonova Research Institute of Reumatology.Russian Federation201707012018020144150Copyright © Елисеев М.С., 20182018Елисеев М.С.Eliseev M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2245

Ключевым медикаментозным методом лечения подагры является уратснижающая терапия, назначение которой в клинической практике сопряжено с высокой вероятностью ошибок из-за незнания показаний к ней, принципов выбора и правил назначения конкретных препаратов. В статье обсуждены показания к уратснижающей терапии у пациентов с подагрой, цели такой терапии, приведены данные о доступных в РФ уратснижающих препаратах (аллопуринол, фебуксостат).

In the current context, immunosuppressive therapy of systemic rheumatic diseases (RD) is becoming more widespread. At the same time, the active use of immunosuppressors including genetically engineered biological preparations is accompanied by an increase in opportunistic infections. The latter include pneumocystic pneumonia (PPn), which is a serious complication with significant mortality in patients with RD. However, given the heterogeneous data on the risks of specific RH and some or other immunosuppressive therapy, the development of a evidence-based comprehensive guide on the prevention of PPn in rheumatology is currently not possible. Specific guidelines for practical physicians can serve as algorithms of PPn prevention published by different authors, which are sure to be further followed-up (or processed) as new data are accumulated within the framework of the problem under consideration.

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The authors declare that there are no conflicts of interest present.