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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-1-118-122</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2278</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Практика</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Practice</subject></subj-group></article-categories><title-group><article-title>Подходы к терапии депрессий в клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>DIFFERENT APPROACHES TO THERAPY OF DEPRESSIVE DISORDERS IN CLINICAL PRACTICE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волель</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volel</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорокина</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokina</surname><given-names>O. Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>06</day><month>02</month><year>2018</year></pub-date><volume>0</volume><issue>1</issue><fpage>118</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Волель Б.А., Сорокина О.Ю., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Волель Б.А., Сорокина О.Ю.</copyright-holder><copyright-holder xml:lang="en">Volel B.A., Sorokina O.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2278">https://www.med-sovet.pro/jour/article/view/2278</self-uri><abstract><p>Депрессивные расстройства, являясь самой распространенной психической патологией в общесоматической практике, часто выступают в качестве причины утяжеления течения соматической/неврологической патологии, увеличения риска инвалидизации и смертности пациентов. Депрессии по своей клинической структуре неоднородны: наиболее часто встречаются в общей медицине невротические депрессии, нозогении/соматогении, а также соматореактивная циклотимия. В связи с разнообразием встречающихся клинических форм аффективных заболеваний необходимо их своевременное выявление и проведение соответствующей дифференцированной антидепрессивной терапии. В качестве назначаемого лекарственного препарата следует делать выбор в пользу антидепрессанта, обладающего оптимально сбалансированным действием, меньшим количеством побочных эффектов, в минимальной степени взаимодействующим с другими лекарственными средствами.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>Depressive disorders, being the most common psychiatric pathology in general somatic practice, often act as a cause of aggravation of somatic/neurological pathology, increasing the risk of disability and death of patients. There is no uniform clinical pattern to the depressive disorders. Neurotic depression, nosogeny/somatogeny, and somatoreactive cyclothymia are the most common in the general medicine. Due to variety of clinical forms of affective diseases, they should be detected in a timely manner and referred for appropriate differentiated antidepressant treatment. As a prescribed drug, you should opt for an antidepressant that has an optimally balanced effect, fewer side effects and a minimal interaction with other drugs.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>депрессивное расстройство</kwd><kwd>невротическая депрессия</kwd><kwd>депрессия в общей медицине</kwd><kwd>нозогения</kwd><kwd>соматогения</kwd><kwd>антидепрессант</kwd></kwd-group><kwd-group xml:lang="en"><kwd>depressive disorder</kwd><kwd>neurotic depression</kwd><kwd>depression in general medicine</kwd><kwd>nosogeny</kwd><kwd>somatogeny</kwd><kwd>antidepressant</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wittchen Н-U. Continued needs for epidemiological studies of mental disorders in the community. Psychother Psychosom, 2004, 73(4): 197-206.</mixed-citation><mixed-citation xml:lang="en">Wittchen Н-U. Continued needs for epidemiological studies of mental disorders in the community. Psychother Psychosom, 2004, 73(4): 197-206.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ohayon ММ. Epidemiology of depression and its treatment in general population. J Psychiatr Res, 2007, 41(3-4): 207-13.</mixed-citation><mixed-citation xml:lang="en">Ohayon ММ. Epidemiology of depression and its treatment in general population. J Psychiatr Res, 2007, 41(3-4): 207-13.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Смулевич А.Б. Депрессии при психических и соматических заболеваниях. М.: Медицинское информационное агентство, 2015, 600 с.</mixed-citation><mixed-citation xml:lang="en">Смулевич А.Б. Депрессии при психических и соматических заболеваниях. М.: Медицинское информационное агентство, 2015, 600 с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Игумнов С.А., Осипчик С.И. Экономический анализ мероприятий в области охраны психического здоровья. Социальная и клиническая психиатрия, 2012, 22(2): 78-80.</mixed-citation><mixed-citation xml:lang="en">Игумнов С.А., Осипчик С.И. Экономический анализ мероприятий в области охраны психического здоровья. Социальная и клиническая психиатрия, 2012, 22(2): 78-80.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobi F, Wittchen H-U, Holting C, Höfler M, Pfister H, Müller N, et al. Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS). Psychol Med, 2004, 34(4): 597-611.</mixed-citation><mixed-citation xml:lang="en">Jacobi F, Wittchen H-U, Holting C, Höfler M, Pfister H, Müller N, et al. Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS). Psychol Med, 2004, 34(4): 597-611.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Андрющенко А.В. Психические и психосоматические расстройства в учреждениях общесоматической сети (клинико-эпидемиологические аспекты, психосоматические соотношения, терапия): Автореферат на соискание ученой степени доктора медицинских наук. М., 2011.</mixed-citation><mixed-citation xml:lang="en">Андрющенко А.В. Психические и психосоматические расстройства в учреждениях общесоматической сети (клинико-эпидемиологические аспекты, психосоматические соотношения, терапия): Автореферат на соискание ученой степени доктора медицинских наук. М., 2011.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Оганов Р.Г., Ольбинская Л.И., Смулевич А.Б., Дробижев М.Ю., Шальнова С.А., Погосова Г.В. Депрессии и расстройства депрессивного спектра в общемедицинской практике. Результаты программы КОМПАС. Кардиология, 2004, 1: 48-54.</mixed-citation><mixed-citation xml:lang="en">Оганов Р.Г., Ольбинская Л.И., Смулевич А.Б., Дробижев М.Ю., Шальнова С.А., Погосова Г.В. Депрессии и расстройства депрессивного спектра в общемедицинской практике. Результаты программы КОМПАС. Кардиология, 2004, 1: 48-54.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Смулевич А.Б., Дубницкая Э.Б., Дробижев М.Ю., Бурлаков А.В., Макух Е.А., Горбушин А.Г. Депрессии и возможности их лечения в общесоматической практике (предварительные результаты программы ПАРУС). Психические расстройства в общей медицине, 2007, 2: 25-30.</mixed-citation><mixed-citation xml:lang="en">Смулевич А.Б., Дубницкая Э.Б., Дробижев М.Ю., Бурлаков А.В., Макух Е.А., Горбушин А.Г. Депрессии и возможности их лечения в общесоматической практике (предварительные результаты программы ПАРУС). Психические расстройства в общей медицине, 2007, 2: 25-30.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Davidson K.W., Kupfer D.J., Bigger J.T., Califf R.M., Carney R.M., Coyne J.C., et al. Assessment and treatment of depression in patient with cardiovascular disease: National Heart, Lung, and Blood Institute Working Group Report. Psychosom Med, 2006, 68(5): 645-50.</mixed-citation><mixed-citation xml:lang="en">Davidson K.W., Kupfer D.J., Bigger J.T., Califf R.M., Carney R.M., Coyne J.C., et al. Assessment and treatment of depression in patient with cardiovascular disease: National Heart, Lung, and Blood Institute Working Group Report. Psychosom Med, 2006, 68(5): 645-50.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Степанова Е.А. Депрессии при ишемической болезни сердца: Автореферат на соискание ученой степени кандидата медицинских наук. М.; 2010.</mixed-citation><mixed-citation xml:lang="en">Степанова Е.А. Депрессии при ишемической болезни сердца: Автореферат на соискание ученой степени кандидата медицинских наук. М.; 2010.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Starkstein SE, Merello M, Jorge R, Brockman S, Bruce D, Petracca G, et al. A validation study of depressive syndromes in Parkinson’s disease. Mov Disord, 2008, 23(4): 538-46.</mixed-citation><mixed-citation xml:lang="en">Starkstein SE, Merello M, Jorge R, Brockman S, Bruce D, Petracca G, et al. A validation study of depressive syndromes in Parkinson’s disease. Mov Disord, 2008, 23(4): 538-46.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Tumas V, Rodrigues GG, Farias TL, Crippa JA. The accuracy of diagnosis of major depression in patients with Parkinson’s disease: a comparative study among the UPDRS, the geriatric depression scale and the Beck depression inventory. Arq Neuropsiquiatr, 2008, 66(2A): 152-6.</mixed-citation><mixed-citation xml:lang="en">Tumas V, Rodrigues GG, Farias TL, Crippa JA. The accuracy of diagnosis of major depression in patients with Parkinson’s disease: a comparative study among the UPDRS, the geriatric depression scale and the Beck depression inventory. Arq Neuropsiquiatr, 2008, 66(2A): 152-6.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Нодель М.Р., Яхно Н.Н. Нервно-психические нарушения при болезни Паркинсона. Неврология, нейропсихиатрия, психосоматика, 2009, 2: 3-8.</mixed-citation><mixed-citation xml:lang="en">Нодель М.Р., Яхно Н.Н. Нервно-психические нарушения при болезни Паркинсона. Неврология, нейропсихиатрия, психосоматика, 2009, 2: 3-8.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Williams LS, Shoma Ghose S, Swindle RW. Depression and other mental health diagnoses increase mortality risk after ischemic stroke. Am J Psychiatry, 2004, 161: 1090-5.</mixed-citation><mixed-citation xml:lang="en">Williams LS, Shoma Ghose S, Swindle RW. Depression and other mental health diagnoses increase mortality risk after ischemic stroke. Am J Psychiatry, 2004, 161: 1090-5.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gaete JM, Bogousslavsky J. Post-stroke depression. Exp Rev Neuroter, 2008, 8: 75-92.</mixed-citation><mixed-citation xml:lang="en">Gaete JM, Bogousslavsky J. Post-stroke depression. Exp Rev Neuroter, 2008, 8: 75-92.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Парфенов В.А. Постинсультная депрессия: распространенность, патогенез, диагностика и лечение. Неврология, нейропсихиатрия, психо-соматика, 2012, 4: 84-8.</mixed-citation><mixed-citation xml:lang="en">Парфенов В.А. Постинсультная депрессия: распространенность, патогенез, диагностика и лечение. Неврология, нейропсихиатрия, психо-соматика, 2012, 4: 84-8.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Joy AB, Hudes M. High risk of depression among low-income women raises awareness about treatment options. California Agriculture, 2010, 61(1): 22-5.</mixed-citation><mixed-citation xml:lang="en">Joy AB, Hudes M. High risk of depression among low-income women raises awareness about treatment options. California Agriculture, 2010, 61(1): 22-5.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Foran HM, Vivian D, O’Leary KD Klein DN, Rothbaum BO, Manber R, et al. Risk for Partner Victimization and Marital Dissatisfaction Among Chronically Depressed Patients. J Fam Viol, 2012, 27: 75-85.</mixed-citation><mixed-citation xml:lang="en">Foran HM, Vivian D, O’Leary KD Klein DN, Rothbaum BO, Manber R, et al. Risk for Partner Victimization and Marital Dissatisfaction Among Chronically Depressed Patients. J Fam Viol, 2012, 27: 75-85.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Сорокина О.Ю., Читлова В.В. Невротическая депрессия (обзор литературы). Психические расстройства в общей медицине, 2016, 4: 28-33.</mixed-citation><mixed-citation xml:lang="en">Сорокина О.Ю., Читлова В.В. Невротическая депрессия (обзор литературы). Психические расстройства в общей медицине, 2016, 4: 28-33.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Лакосина Н.Д. Клинические варианты невротического развития. М.: Медицина, 1970, 218 с.</mixed-citation><mixed-citation xml:lang="en">Лакосина Н.Д. Клинические варианты невротического развития. М.: Медицина, 1970, 218 с.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Лакосина Н.Д., Трунова М.М. Неврозы, невротические развития личности и психопатии: клиника и лечение. М.: Медицина, 1994, 192 с.</mixed-citation><mixed-citation xml:lang="en">Лакосина Н.Д., Трунова М.М. Неврозы, невротические развития личности и психопатии: клиника и лечение. М.: Медицина, 1994, 192 с.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Roth M, Mountjoy CQ. The need for the concept of neurotic depression. In: Akiskal HS, Cassano GB (eds), Dysthymia and the spectrum of chronic depressions. New York: Guilford press, 1997, 96-129.</mixed-citation><mixed-citation xml:lang="en">Roth M, Mountjoy CQ. The need for the concept of neurotic depression. In: Akiskal HS, Cassano GB (eds), Dysthymia and the spectrum of chronic depressions. New York: Guilford press, 1997, 96-129.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ghaemi SN, Vöhringer PA. The heterogeneity of depression: an old debate renewed. Acta Psychiat Scand, 2011, 124: 497.</mixed-citation><mixed-citation xml:lang="en">Ghaemi SN, Vöhringer PA. The heterogeneity of depression: an old debate renewed. Acta Psychiat Scand, 2011, 124: 497.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ghaemi SN, Vöhringer PA, Vergne DE. The varieties of depressive Experience: diagnosing mood disorders. Psychiat Clin N Am, 2012, 35: 73-86.</mixed-citation><mixed-citation xml:lang="en">Ghaemi SN, Vöhringer PA, Vergne DE. The varieties of depressive Experience: diagnosing mood disorders. Psychiat Clin N Am, 2012, 35: 73-86.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Brautigam W. Reaktionen - Neurosen - Abnorme Persoenlichkeiten. Seelische Krankheiten im Grudriss. Stuttgart: Georg Thieme Verlag, 1978: 134-42.</mixed-citation><mixed-citation xml:lang="en">Brautigam W. Reaktionen - Neurosen - Abnorme Persoenlichkeiten. Seelische Krankheiten im Grudriss. Stuttgart: Georg Thieme Verlag, 1978: 134-42.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Kissane DW, Clarke DM, Street AF. Demoralization syndrome - a relevant psychiatric diagnosis for palliative care. J Palliat Care, 2001, 17(1): 12-21.</mixed-citation><mixed-citation xml:lang="en">Kissane DW, Clarke DM, Street AF. Demoralization syndrome - a relevant psychiatric diagnosis for palliative care. J Palliat Care, 2001, 17(1): 12-21.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Capaldi V, Wynn I. Emerging strategies in the treatment of post-stroke depression and psychiatric distress in patients. Psychol Res Behav Manag, 2010, 3: 109-118.</mixed-citation><mixed-citation xml:lang="en">Capaldi V, Wynn I. Emerging strategies in the treatment of post-stroke depression and psychiatric distress in patients. Psychol Res Behav Manag, 2010, 3: 109-118.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Самушия М.А. Психические расстройства у больных злокачественными новообразованиями органов женской репродуктивной системы (клиника, эпидемиология, терапия): Автореферат на соискание ученой степени доктора медицинских наук. М., 2015.</mixed-citation><mixed-citation xml:lang="en">Самушия М.А. Психические расстройства у больных злокачественными новообразованиями органов женской репродуктивной системы (клиника, эпидемиология, терапия): Автореферат на соискание ученой степени доктора медицинских наук. М., 2015.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Волель Б.А., Макух Е.А., Лебедева М.В., Попова Е.Н. К проблеме психосоматических расстройств при саркоидозе (на базе материалов межклинической конференции «Саркоидоз как системное заболевание: соматические и психические расстройства. Психические расстройства в общей медицине, 2015, 2-3: 31-39.</mixed-citation><mixed-citation xml:lang="en">Волель Б.А., Макух Е.А., Лебедева М.В., Попова Е.Н. К проблеме психосоматических расстройств при саркоидозе (на базе материалов межклинической конференции «Саркоидоз как системное заболевание: соматические и психические расстройства. Психические расстройства в общей медицине, 2015, 2-3: 31-39.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Мосолов С.Н., Костюкова Е.Г., Ушкалова А.В. Клиника и терапия биполярной депрессии. М.: АМА-ПРЕСС, 2009, 48 с.</mixed-citation><mixed-citation xml:lang="en">Мосолов С.Н., Костюкова Е.Г., Ушкалова А.В. Клиника и терапия биполярной депрессии. М.: АМА-ПРЕСС, 2009, 48 с.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">van Melle JP, de Jonge P, Spijkerman TA, Tijssen JG, Ormel J, van Veldhuisen DJ, et al. Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis. Psychosom Med, 2004, 66(6): 814-22.</mixed-citation><mixed-citation xml:lang="en">van Melle JP, de Jonge P, Spijkerman TA, Tijssen JG, Ormel J, van Veldhuisen DJ, et al. Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis. Psychosom Med, 2004, 66(6): 814-22.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Glassman AH, O’Connor CM, Califf RM, Swed-berg K, Schwartz P, Bigger JT Jr, et al. Sertraline Antidepressant Heart Attack Rando mized Trial (SADHART) Group. Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA, 2002, 288: 701–9.</mixed-citation><mixed-citation xml:lang="en">Glassman AH, O’Connor CM, Califf RM, Swed-berg K, Schwartz P, Bigger JT Jr, et al. Sertraline Antidepressant Heart Attack Rando mized Trial (SADHART) Group. Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA, 2002, 288: 701–9.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Petrak F, Herpertz S, Albus C, Hermanns N, Hiemke C, Hiller F, et al. Cognitive behavioral therapy versus sertraline in patients with depression and poorly controlled diabetes: the diabetes and depression (DAD) study: A rand-omized controlled multicenter Trial. Diabetes Care, 2015, 38(5): 767-75.</mixed-citation><mixed-citation xml:lang="en">Petrak F, Herpertz S, Albus C, Hermanns N, Hiemke C, Hiller F, et al. Cognitive behavioral therapy versus sertraline in patients with depression and poorly controlled diabetes: the diabetes and depression (DAD) study: A rand-omized controlled multicenter Trial. Diabetes Care, 2015, 38(5): 767-75.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Sherwood A Blumenthal JA, Smith PJ, Watkins LL, Hoffman BM, Hinderliter AL. Effects of exercise and sertraline on measures of coronary heart disease risk in patients with major depression: results from the SMILE-II randomized clinical trial. Psychosom Med, 2016, 78(5): 602-9.</mixed-citation><mixed-citation xml:lang="en">Sherwood A Blumenthal JA, Smith PJ, Watkins LL, Hoffman BM, Hinderliter AL. Effects of exercise and sertraline on measures of coronary heart disease risk in patients with major depression: results from the SMILE-II randomized clinical trial. Psychosom Med, 2016, 78(5): 602-9.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Hedayati SS, Gregg LP, Carmody T, Jain N, Toups M, Rush AJ, et al. Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial. JAMA, 2017, 318(19): 1876-90.</mixed-citation><mixed-citation xml:lang="en">Hedayati SS, Gregg LP, Carmody T, Jain N, Toups M, Rush AJ, et al. Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial. JAMA, 2017, 318(19): 1876-90.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, Churchill R, et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatment meta-analysis. Lancet, 2009, 373: 746-58.</mixed-citation><mixed-citation xml:lang="en">Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, Churchill R, et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatment meta-analysis. Lancet, 2009, 373: 746-58.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Выборных Д.Э. Терапия депрессивных рас-стройств у больных гемобластозами. Проблемы гематологии и переливания крови, 2004, 3: 40-41.</mixed-citation><mixed-citation xml:lang="en">Выборных Д.Э. Терапия депрессивных рас-стройств у больных гемобластозами. Проблемы гематологии и переливания крови, 2004, 3: 40-41.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Broen MP, Leentjens AF, Köhler S, Kuijf ML, McDonald WM, Richard IH. Trajectories of recovery in depressed Parkinson’s disease patients treated with paroxetine or venlafaxine. Parkinsonism Relat Disord, 2016, 23: 80-5.</mixed-citation><mixed-citation xml:lang="en">Broen MP, Leentjens AF, Köhler S, Kuijf ML, McDonald WM, Richard IH. Trajectories of recovery in depressed Parkinson’s disease patients treated with paroxetine or venlafaxine. Parkinsonism Relat Disord, 2016, 23: 80-5.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Watanabe N, Omori IM, Nakagawa A, Cipriani A, Barbui C, McGuire H, et al. Mirtazapine versus other antidepressants in the acute-phase treatment of adults with major depression: systematic review and meta-analysis. J Clin Psychiatry, 2008, 69(9): 1404-15.</mixed-citation><mixed-citation xml:lang="en">Watanabe N, Omori IM, Nakagawa A, Cipriani A, Barbui C, McGuire H, et al. Mirtazapine versus other antidepressants in the acute-phase treatment of adults with major depression: systematic review and meta-analysis. J Clin Psychiatry, 2008, 69(9): 1404-15.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Lichtman JH, Bigger JT Jr, Blumenthal JA, Frasure-Smith N, Kaufmann PG, Lesperance F, et al. Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association. Circulation, 2008, 118(17): 1768-75.</mixed-citation><mixed-citation xml:lang="en">Lichtman JH, Bigger JT Jr, Blumenthal JA, Frasure-Smith N, Kaufmann PG, Lesperance F, et al. Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association. Circulation, 2008, 118(17): 1768-75.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Смулевич А.Б., Сыркин А.Л., Дробижев М.Ю., Иванов С.В. Психокардиология. М.: Медицинское информационное агентство, 2005, 784 с.</mixed-citation><mixed-citation xml:lang="en">Смулевич А.Б., Сыркин А.Л., Дробижев М.Ю., Иванов С.В. Психокардиология. М.: Медицинское информационное агентство, 2005, 784 с.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Taylor D. Antidepressant drugs and cardiovascular pathology: a clinical overview of effectiveness and safety. Acta Psychiatr Scand, 2008, 118(6): 434-42.</mixed-citation><mixed-citation xml:lang="en">Taylor D. Antidepressant drugs and cardiovascular pathology: a clinical overview of effectiveness and safety. Acta Psychiatr Scand, 2008, 118(6): 434-42.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Serebruany VL, Glassman AH, Malinin AI, Nemeroff CB, Musselman DL, van Zyl LT, et al. Sertraline Antidepressant Heart Attack Randomized Trial Study Group. Platelet/ endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline Antidepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy. Circulation, 2003, 108: 939–44.</mixed-citation><mixed-citation xml:lang="en">Serebruany VL, Glassman AH, Malinin AI, Nemeroff CB, Musselman DL, van Zyl LT, et al. Sertraline Antidepressant Heart Attack Randomized Trial Study Group. Platelet/ endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline Antidepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy. Circulation, 2003, 108: 939–44.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Mokhber N, Abdollahian E, Soltanifar A, Samadi R, Saghebi A, Haghighi MB, et al. Comparison of sertraline, venlafaxine and desipramine effects on depression, cognition and the daily living activities in Alzheimer patients. Pharmacopsychiatry, 2014, 47(4-5): 131-40.</mixed-citation><mixed-citation xml:lang="en">Mokhber N, Abdollahian E, Soltanifar A, Samadi R, Saghebi A, Haghighi MB, et al. Comparison of sertraline, venlafaxine and desipramine effects on depression, cognition and the daily living activities in Alzheimer patients. Pharmacopsychiatry, 2014, 47(4-5): 131-40.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Strik JJ, Honig A, Lousberg R, Lousberg AH, Cheriex EC, Tuynman-Qua HG, et al. Efficacy and safety of fluoxetine in the treatment of patients with major depression after first myocardial infarction: findings from a double-blind, placebo-controlled trial. Psychosom Med, 2000, 62: 783–9.</mixed-citation><mixed-citation xml:lang="en">Strik JJ, Honig A, Lousberg R, Lousberg AH, Cheriex EC, Tuynman-Qua HG, et al. Efficacy and safety of fluoxetine in the treatment of patients with major depression after first myocardial infarction: findings from a double-blind, placebo-controlled trial. Psychosom Med, 2000, 62: 783–9.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Pohl R, Balon R, Jayaraman A, Doll RG, Yeragani V. Effect of fluoxetine, pemoline and placebo on heart period and QT variability in normal humans. J. Psychosom Res, 2003, 55: 247–51.</mixed-citation><mixed-citation xml:lang="en">Pohl R, Balon R, Jayaraman A, Doll RG, Yeragani V. Effect of fluoxetine, pemoline and placebo on heart period and QT variability in normal humans. J. Psychosom Res, 2003, 55: 247–51.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Lesperance F, Frasure-Smith N, Koszycki D, Laliberte MA, van Zyl LT, Baker B, et al. Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA, 2007, 297(4): 367-79.</mixed-citation><mixed-citation xml:lang="en">Lesperance F, Frasure-Smith N, Koszycki D, Laliberte MA, van Zyl LT, Baker B, et al. Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA, 2007, 297(4): 367-79.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Kimmel SE, Schelleman H, Berlin JA, Oslin DW, Weinstein RB, Kinman JL, et al. The effect of selective serotonin re-uptake inhibitors on the risk of myocardial infarction in a cohort of patients with depression. Br J Clin Pharmacol, 2011, 72(3): 514-7.</mixed-citation><mixed-citation xml:lang="en">Kimmel SE, Schelleman H, Berlin JA, Oslin DW, Weinstein RB, Kinman JL, et al. The effect of selective serotonin re-uptake inhibitors on the risk of myocardial infarction in a cohort of patients with depression. Br J Clin Pharmacol, 2011, 72(3): 514-7.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Starkstein S.E., Mizrahi R, Power BD. Antidepressant therapy in post-stroke depression. Expert Opin Pharmacother, 2008, 9(8): 1291-8.</mixed-citation><mixed-citation xml:lang="en">Starkstein S.E., Mizrahi R, Power BD. Antidepressant therapy in post-stroke depression. Expert Opin Pharmacother, 2008, 9(8): 1291-8.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
