medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2015-8-55-59medsovet-229Research ArticleОНКОЛОГИЯ И ОНКОГЕМАТОЛОГИЯONCOLOGY AND ONCOHEMATOLOGYВторая линия противоопухолевой терапии метастатического колоректального рака: стратегия леченияSecond line anti-cancer therapy for metastatic colorectal cancer: treatment strategyВоронцоваК. А.VorontsovaK. A.noemail@neicon.ruДоброваН. В.DobrovaN. V.noemail@neicon.ruВышинскаяГ. В.VyshinskayaG. V.noemail@neicon.ruРоссийский онкологический научный центр им. Н.Н. Блохина, МоскваРоссияN. N. Blokhin Cancer Research Center, MoscowRussian Federation201530122015085559Copyright © Воронцова К.А., Доброва Н.В., Вышинская Г.В., 20152015Воронцова К.А., Доброва Н.В., Вышинская Г.В.Vorontsova K.A., Dobrova N.V., Vyshinskaya G.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/229

Колоректальный рак занимает одну из лидирующих позиций в мире в структуре онкологической заболеваемости. За последние десятилетия достигнуты значительные успехи в лечении метастатического колоректального рака. Однако расширение спектра эффективных противоопухолевых препаратов формирует и ряд сложностей при выборе оптимальных схем лекарственной терапии у больных с метастазами колоректального рака. В статье изложены современные аспекты II линии лечения метастатического колоректального рака, рекомендации по выбору режимов химиотерапии и назначению таргет-ных препаратов.

Colorectal cancer is one of the most widespread cancers globally. Over the past decade, there has been a significant progress in the treatment of metastatic colorectal cancer. However, an increase in the range of effective anticancer drugs is associated with a number of difficulties in determining the adequate drug treatment regimens for patients with metastatic colorectal cancer. The article describes the current aspects of II line treatment of metastatic colorectal cancer, guidelines for the selection of chemotherapy regimens and appointment of targeted drugs.

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The authors declare that there are no conflicts of interest present.