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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-4-20-27</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2327</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>САХАРНЫЙ ДИАБЕТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DIABETES MELLITUS</subject></subj-group></article-categories><title-group><article-title>Метформин – общепризнанный препарат первого выбора у больных сахарным диабетом 2-го типа</article-title><trans-title-group xml:lang="en"><trans-title>Metformin is the most recognized first choice drug for patients with type 2 diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мкртумян</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Mkrtumyan</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор</p></bio><bio xml:lang="en"><p>MD, Prof</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I.Yevdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>29</day><month>03</month><year>2018</year></pub-date><volume>0</volume><issue>4</issue><fpage>20</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мкртумян А.М., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Мкртумян А.М.</copyright-holder><copyright-holder xml:lang="en">Mkrtumyan A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2327">https://www.med-sovet.pro/jour/article/view/2327</self-uri><abstract><p>Для терапии сахарного диабета 2-го типа могут использоваться препараты сульфонилмочевины, глиниды, ингибиторы a-глюкозидазы, тиазолидиндионы, инкретины, аналоги ГПП-1, иНГЛТ-2 и, конечно, метформин. Он занимает центральную позицию, учитывая его роль в снижении гипергликемии и риска развития угрожающих жизни осложнений. Международная федерация по сахарному диабету ежегодно подтверждает целесообразность назначения метформина в качестве первого шага для лечения сахарного диабета 2-го типа наряду с модификацией образа жизни [<xref ref-type="bibr" rid="cit1">1</xref>].</p></abstract><trans-abstract xml:lang="en"><p>Many anti-diabetic drugs are now available to treat type 2 diabetes mellitus, including sulfonylureas, glinides, α-glucosidase inhibitors, thiazolidinediones, incretin-related drugs, glucagon-like peptide-1 (GLP-1) analogues, sodium-glucose co-transporter 2 (SGLT2) inhibitors and, certainly, metformin. It holds a central position, given its role in reducing hyperglycemia and the risk of life-threatening complications. The International Diabetes Federation annually confirms the appropriateness of the appointment of metformin as a first step in the treatment of type 2 diabetes mellitus along with lifestyle modification [<xref ref-type="bibr" rid="cit1">1</xref>].</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет 2-го типа</kwd><kwd>фармакотерапия</kwd><kwd>метформин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>type 2 diabetes mellitus</kwd><kwd>pharmacotherapy</kwd><kwd>metformin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Atlas: www.idf.org/diabetesatlas.org IDF Diabetes Atlas 7th edition, 2015 online version of IDF.</mixed-citation><mixed-citation xml:lang="en">Atlas: www.idf.org/diabetesatlas.org IDF Diabetes Atlas 7th edition, 2015 online version of IDF.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Шестакова М.В., Майоров А.Ю. 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