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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-5-122-126</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2354</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTANT</subject></subj-group></article-categories><title-group><article-title>Структурно-функциональные изменения миокарда и клапанов сердца у больных коронарной патологией старших возрастных групп</article-title><trans-title-group xml:lang="en"><trans-title>Structural and functional changes of the myocardium and heart valves in patients of advanced and senile age with coronary pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никифоров</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikiforov</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никищенкова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikishchenkova</surname><given-names>Yu. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Северо-Западный государственный медицинский университет им. И.И. Мечникова Минздрава России, Санкт-Петербург<country>Россия</country></aff><aff xml:lang="en">Mechnikov North-Western State Medical University of the Ministry of Health of Russia, St.Petersburg<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Госпиталь для ветеранов войн, Санкт-Петербург<country>Россия</country></aff><aff xml:lang="en">War Veterans Hospital, St.Petersburg<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2018</year></pub-date><volume>0</volume><issue>5</issue><fpage>122</fpage><lpage>126</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никифоров В.С., Никищенкова Ю.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Никифоров В.С., Никищенкова Ю.В.</copyright-holder><copyright-holder xml:lang="en">Nikiforov V.S., Nikishchenkova Y.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2354">https://www.med-sovet.pro/jour/article/view/2354</self-uri><abstract><p>Целью данной работы было изучение структурно-функциональных изменений миокарда и клапанов сердца у больных коронарной патологией пожилого и старческого возраста. Обследовано 128 лиц с ишемической болезнью сердца 82,4 ± 10,6 года (от 65 до 90 лет), которые, в соответствии с классификацией ВОЗ, были разделены на две возрастные группы: 1-я – лица пожилого возраста – от 65 до 74 лет (32%), 2-я – лица старческого возраста – от 75 до 90 лет (68%). Всем обследуемым выполнялись сбор анамнеза, физикальный осмотр, электрокардиография, эхокардиография с тканевой допплерографией, оценка глобальной продольной деформации с помощью методики 2D-speckle-tracking, коронароангиография. У больных коронарной патологией пожилого и старческого возраста выявлены структурно-функциональные изменения миокарда, связанные с возрастом, многососудистым поражением коронарных артерий, наличием в анамнезе перенесенного инфаркта миокарда, а также сопутствующей патологией (артериальная гипертензия). При этом у лиц старше 75 лет отмечается прогрессирование коронарной патологии, систолической и диастолической дисфункции, кальциноза аортального клапана, комбинированных пороков аортального и митрального клапанов, а также увеличение числа лиц с гипертрофией левого желудочка. Показана информативность эхокардиографической оценки глобальной продольной деформации миокарда для выявления субклинической систолической дисфункции миокарда у больных коронарной патологией пожилого и старческого возраста.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>This paper was aimed at studying the structural and functional changes in the myocardium and heart valves in patients of advanced and senile age with coronary pathology. 128 patients with coronary heart disease were examined; the average age was 82.4 ± 10.6 years (from 65 to 90 years old). According to the WHO classification, the patients were divided into two age groups: 1st – elderly people – from 65 to 74 years (32%), 2nd – senile people – from 75 to 90 years (68%). All subjects underwent anamnesis, physical examination, electrocardiography, echocardiography with tissue dopplerography, assessment of global longitudinal strain using a 2D-speckle-tracking technique, coronaroangiography. Patients of elderly and senile age with coronary pathology have age-associated structural and functional myocardial changes, multivessel lesions in the coronary arteries, history of previous myocardial infarction, as well as concomitant pathology (arterial hypertension). The patients older than 75 years have a progression of coronary pathology, systolic and diastolic dysfunction, aortic valve calcification, combined aortic and mitral valve defects, also the number of people with left ventricular hypertrophy is increasing. The number of people with left ventricular hypertrophy is increasing. The study showed informative value of echocardiographic evaluation of global longitudinal myocardial strain to identify the subclinical systolic dysfunction of the myocardium in patients of elderly and senile age with coronary pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>коронарная патология</kwd><kwd>пожилой и старческий возраст</kwd><kwd>дисфункция левого желудочка</kwd><kwd>эхокардиография</kwd><kwd>глобальная продольная деформация миокарда</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ischemic heart disease</kwd><kwd>coronary pathology</kwd><kwd>advanced and senile age</kwd><kwd>left ventricular dysfunction</kwd><kwd>echocardiography</kwd><kwd>global longitudinal myocardial strain</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dodson JA, Matlock DD, Forman DE. Geriatric Cardiology: An Emerging Discipline. 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