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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-6-26-32</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2368</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY</subject></subj-group></article-categories><title-group><article-title>Фармакологические принципы терапии инсомнии</article-title><trans-title-group xml:lang="en"><trans-title>Pharmacotherapy treatment principles for insomnia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оковитый</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Okovityi</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титович</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Titovich</surname><given-names>I. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Санкт-Петербургский государственный химико-фармацевтический университет Минздрава России<country>Россия</country></aff><aff xml:lang="en">Saint Petersburg State Chemical Pharmaceutical University of the Ministry of Health of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>12</day><month>04</month><year>2018</year></pub-date><volume>0</volume><issue>6</issue><fpage>26</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Оковитый С.В., Титович И.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Оковитый С.В., Титович И.А.</copyright-holder><copyright-holder xml:lang="en">Okovityi S.V., Titovich I.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2368">https://www.med-sovet.pro/jour/article/view/2368</self-uri><abstract><p>Фармакотерапия инсомнии является неотъемлемой частью лечения этого клинического синдрома. Спектр препаратов, используемых при нарушениях сна, весьма обширен, причем не все они относятся к «истинным» снотворным средствам, а нередко являются представителями различных классов психотропных средств. Современные снотворные препараты при соблюдении необходимых правил позволяют получить необходимое снотворное действие, не сопровождающееся негативными изменениями структуры сна и качества последующего бодрствования. Результаты отечественных и зарубежных исследований, рекомендации ведущих профессиональных сообществ (Российского общества сомнологов  – 2016; European Sleep Research Society – 2017; American Academy of Sleep Medicine – 2017; American College of Physicians – 2016) позволяют утверждать, что нормализация сна при инсомнии, в т. ч. с использованием фармакотерапии, нейтрализует ее негативное воздействие, повышает адаптивные возможности человека и способствует предотвращению развития хронических нарушений сна с их серьезными неблагоприятными последствиями.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>Pharmacotherapy of insomnia is an integral part of the treatment of this clinical syndrome. The range of drugs used for the treatment of sleep disorders is quite extensive, and not all of them are “true” sleeping pills”. Such pills often belong to the various classes of psychotropic medications. Advanced sleeping pills taken in compliance with the necessary rules provide the necessary sleeping effect without accompanied negative changes in the sleep structure and the quality of the subsequent waking. The domestic and foreign studies, the leading professional community guidelines (the Russian Society of Somanologists – 2016, the European Sleep Research Society – 2017, the American Academy of Sleep Medicine – 2017, the American College of Physicians – 2016) show that normalization of sleep in patients with insomnia by various methods, including pharmacotherapy, neutralizes its negative effects, improves the adaptive capacity of the individual and prevents the chronic sleep disorders with severe adverse effects.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инсомния</kwd><kwd>когнитивно-поведенческая терапия</kwd><kwd>фармакотерапия</kwd><kwd>снотворные средства</kwd><kwd>агонисты бензодиазепиновых рецепторов</kwd><kwd>агонисты мелатониновых рецепторов</kwd><kwd>антагонисты Н1-гистаминовых рецепторов</kwd><kwd>доксиламин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>insomnia</kwd><kwd>cognitive-behavioral therapy</kwd><kwd>pharmacotherapy</kwd><kwd>sleeping agents</kwd><kwd>benzodiazepine receptor agonists</kwd><kwd>melatonin receptor agonists</kwd><kwd>H1-histamine receptor antagonists</kwd><kwd>doxylamine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lichstein KL, Taylor DJ, McCrae CS, Petrov ME. 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