medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2018-6-78-82medsovet-2378Research ArticleБРОНХОПУЛЬМОНОЛОГИЯ. ЛОРBRONCHOPULMONOLOGY. ENTОсобенности антибактериальной терапии острого гнойного синусита и острого гнойного среднего отитаFeatures of antibacterial therapy of acute purulent sinusitis and acute purulent otitis mediaГуровА. В.GurovA. V.

д.м.н., профессор

 

MD, Prof.

Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России; Научно-исследовательский клинический институт оториноларингологии им. Л.И. Свержевского Департамента здравоохранения г. МосквыРоссияN.I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Sverzhevskiy Otorhinolaryngology Healthcare Research Institute of the Moscow Department of HealthcareRussian Federation201812042018067882Copyright © Гуров А.В., 20182018Гуров А.В.Gurov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2378

В статье представлены современные представления о микробиологических особенностях острого гнойного синусита и острого гнойного среднего отита во взаимосвязи с клиническим течением, показана роль гемофильной палочки в формировании затяжного, рецидивирующего, а также хронического течения процесса. Представлены возможности Панцефа (цефиксима) в терапии и профилактике данных состояний.

The article presents modern views on the microbiological findings of acute purulent sinusitis and acute purulent otitis media in identified in conjunction with clinical course. It shows the role of Haemophilus influenzae in the development of a protracted, recurrent, and chronic course of the process. The therapeutic potentials of Pancef (cefixim) for the treatment and prevention of these conditions are presented.

острый гнойный синуситострый гнойный средний отитH. InfluenzaeПанцеф (цефиксим)acute purulent sinusitisacute purulent middle otitisH. influenzaePancef (cefixim)ReferencesРуководство по очаговой инфекции в оториноларингологии. Под ред. В.Т. Пальчуна, А.И. Крюкова, М.М. Магомедова. М.: ГЕОТАР-Медиа, 2015. 224 с.Guidelines on focal infection in otorhinolaryngology. Edited by Palchun VT, Kryukov AI, Magomedov MM. M.: GEOTAR-MEDIA, 2015. 224 p.Deryugina OV, Chumakov FI. Orbital and intra-cranial complications of inflammatory diseases of the nose and paranasal sinuses in adults and children. M.: MONIKI, 2001, 116 p.Deryugina OV, Chumakov FI. Orbital and intra-cranial complications of inflammatory diseases of the nose and paranasal sinuses in adults and children. M.: MONIKI, 2001, 116 p.Kunelskaya NL, Gurov AV, Kudryavtseva YuS, Kafarskaya LI, Izotova GN. Efficacy of cefixim in patients with acute purulent sinusitis and exacerbation of chronic purulent sinusitis. Vestnik Otorinolaringologii, 2008, 6: 55-58.Kunelskaya NL, Gurov AV, Kudryavtseva YuS, Kafarskaya LI, Izotova GN. Efficacy of cefixim in patients with acute purulent sinusitis and exacerbation of chronic purulent sinusitis. Vestnik Otorinolaringologii, 2008, 6: 55-58.Kryukov AI, Shubin MN. Appropriate antibiotic therapy for acute and sluggish rhinosinusitis. Consilium medicum, 2001, 3 (8): 358-361.Kryukov AI, Shubin MN. Appropriate antibiotic therapy for acute and sluggish rhinosinusitis. Consilium medicum, 2001, 3 (8): 358-361.WHO. Global antimicrobial resistance surveillance system (GLASS) report: Early implementation 2016-2017. [электронный ресурс – дата обращения 10.03.18]. / WHO. Global Antimicrobial Resistance Monitoring System (GLASS) report: Early implementation 2016-2017. [Electronic resource - accessed date 10.03.18].WHO. Global antimicrobial resistance surveillance system (GLASS) report: Early implementation 2016-2017. [электронный ресурс – дата обращения 10.03.18]. / WHO. Global Antimicrobial Resistance Monitoring System (GLASS) report: Early implementation 2016-2017. [Electronic resource - accessed date 10.03.18].Kryukov AI, Kunleskaya NL, Gurov AV, Elchueva ZG, Isotova GN, Muratov DL, Sokolov SС. Topical issues of clinical picture and therapy of acute purulent otitis media. Meditsinsky Sovet, 2015, 7: 8-11.Kryukov AI, Kunleskaya NL, Gurov AV, Elchueva ZG, Isotova GN, Muratov DL, Sokolov SС. Topical issues of clinical picture and therapy of acute purulent otitis media. Meditsinsky Sovet, 2015, 7: 8-11.Palchun VT, Lucichin LA. Advisability and efficacy of antibacterial therapy in ENT practice. Vestnik Otorinolaringologii, 2006, 3: 27-30.Palchun VT, Lucichin LA. Advisability and efficacy of antibacterial therapy in ENT practice. Vestnik Otorinolaringologii, 2006, 3: 27-30.Zubkov MN. The algorithm for the treatment of acute and chronic infections of the upper and lower respiratory tract. RMG, 2009, 17 (2): 123-131.Zubkov MN. The algorithm for the treatment of acute and chronic infections of the upper and lower respiratory tract. RMG, 2009, 17 (2): 123-131.Lopatin AS, Aleksandrova IA, Gamov VP, Detochka YaV. Rational pharmacotherapy for ear, throat and nose disorders: A guide for practitioners. M.: Litterra, 2011: 48-64.Lopatin AS, Aleksandrova IA, Gamov VP, Detochka YaV. Rational pharmacotherapy for ear, throat and nose disorders: A guide for practitioners. M.: Litterra, 2011: 48-64.Strachunsky LS, Kozlov SN. Modern antimicrobial chemotherapy. A guide for practitioners. M.: Borges, 2002. 432 p.Strachunsky LS, Kozlov SN. Modern antimicrobial chemotherapy. A guide for practitioners. M.: Borges, 2002. 432 p.Block SL, Schwartz R.H. Changes noted in bacteriology of OAM since PCV7 (text). Infectious diseases in children, 2003, Aug, 8-16.Block SL, Schwartz R.H. Changes noted in bacteriology of OAM since PCV7 (text). Infectious diseases in children, 2003, Aug, 8-16.Brink AJ et al. Guideline for the management of upper respiratory tract infections (text). S Afr Med J, 2004 Jun, 94(6Pt2): 475-83.Brink AJ et al. Guideline for the management of upper respiratory tract infections (text). S Afr Med J, 2004 Jun, 94(6Pt2): 475-83.England JK, Bauernfeind A, Levenstein J et al. A multicentre randomised comparison of cefixime versus co-trimoxazole in uncomplicated urinary tract infections. Workshop 15th International Congress of Chemotherapy. Advances in experimental and clinical chemotherapy, 1988: 53–60.England JK, Bauernfeind A, Levenstein J et al. A multicentre randomised comparison of cefixime versus co-trimoxazole in uncomplicated urinary tract infections. Workshop 15th International Congress of Chemotherapy. Advances in experimental and clinical chemotherapy, 1988: 53–60.Iravani A, Richard GA, Johnson D et al. Am J Medicine, 1988, 85(Suppl. 3A): 17–85.Iravani A, Richard GA, Johnson D et al. Am J Medicine, 1988, 85(Suppl. 3A): 17–85.Ludwig E. Cefixime in the treatment of respiratory and urinary tract infections. Chemotherapy. 1998, 44(suppl 1): 31-34.Ludwig E. Cefixime in the treatment of respiratory and urinary tract infections. Chemotherapy. 1998, 44(suppl 1): 31-34.Patient Information Leaflet for Pancef®.Patient Information Leaflet for Pancef®.

The authors declare that there are no conflicts of interest present.