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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-6-132-136</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2386</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Эндокринология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Endocrinology</subject></subj-group></article-categories><title-group><article-title>Ожирение и неалкогольная жировая болезнь печени персонализированные подходы коррекции метаболических рисков</article-title><trans-title-group xml:lang="en"><trans-title>Obesity and non-alcoholic fatty liver disease personalized approaches to metabolic risks correction</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комшилова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Komshilova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>чл.-корр. РАН, д.м.н., профессор</p></bio><bio xml:lang="en"><p>Corr. Member of RAS, MD, Prof.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр эндокринологии Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Endocrinology of the Ministry of Health of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>12</day><month>04</month><year>2018</year></pub-date><volume>0</volume><issue>6</issue><fpage>132</fpage><lpage>136</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Комшилова К.А., Трошина Е.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Комшилова К.А., Трошина Е.А.</copyright-holder><copyright-holder xml:lang="en">Komshilova K.A., Troshina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2386">https://www.med-sovet.pro/jour/article/view/2386</self-uri><abstract><p>Неалкогольная жировая болезнь печени (НАЖБП) – это распространенное хроническое заболевание печени, основным признаком которого является накопление жира в гепатоцитах, не связанное со злоупотреблением алкоголем. НАЖБП ассоциирована с ожирением, особенно абдоминальным, метаболическим синдромом и различными метаболическими маркерами риска развития сердечно-сосудистых заболеваний и сахарного диабета 2-го типа, что отражается на заболеваемости, прогнозе и продолжительности жизни больных ожирением. В данной статье изложены основные причины заболевания, его патогенез, клиническая картина, диагностика и лечение.</p></abstract><trans-abstract xml:lang="en"><p>Nonalcoholic fatty liver disease (NAFLD) – a common chronic disease of the liver, the main feature of which is the accumulation of fat in hepatocytes, is not related to alcohol abuse. NAFLD is associated with obesity, especially abdominal, metabolic syndrome and various metabolic markers of risk for cardiovascular disease and type 2 diabetes, which affects the incidence, prognosis and life expectancy of patients with obesity. This lecture describes the main causes of the disease, its pathogenesis, clinical presentation, diagnosis and treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>неалкогольная жировая болезнь печени</kwd><kwd>инсулинорезистентность</kwd><kwd>лираглутид</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>nonalcoholic fatty liver disease</kwd><kwd>insulin resistance</kwd><kwd>liraglutide</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Буеверов А.О. Хронические заболевания печени. Краткое руководство для практикующих врачей. Издательство «МИА», 2013. С. 144.</mixed-citation><mixed-citation xml:lang="en">Bueverov AO. Chronic liver disease. A mini guide for practitioners. 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