medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2018-6-156-160medsovet-2391Research ArticleГИНЕКОЛОГИЯGYNECOLOGYВлияние менопаузальной гормональной терапии на кожу как компонент здорового старенияEffect of menopausal hormone therapy on the skin as a component of healthy agingЮреневаС. В.YurenevaS. V.

д.м.н.

MD

ИльинаЛ. М.IlyinaL. M.

к.м.н.

PhD in medicine

Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова Минздрава России, МоскваРоссияV.I. Kulakov National Medical Research Centre for Obstetrics, Gynaecology and Perinatology of the Ministry of Health of Russia, MoscowRussian Federation20181304201806156160Copyright © Юренева С.В., Ильина Л.М., 20182018Юренева С.В., Ильина Л.М.Yureneva S.V., Ilyina L.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2391

Здоровое старение (anti-aging; антистарение) предполагает профилактику заболеваний и нетрудоспособности, сохранение высокой ментальной и физической активности, поддержание смысла и цели жизни. Женщины отказываются стареть и хотят выглядеть моложе как можно дольше. Кожа является единственным органом, состояние которого можно оценить визуально, своеобразным зеркалом, отражающим происходящие в организме возрастные изменения и состояние здоровья в целом. Все закономерные возрастные процессы на клеточном уровне происходят в коже, поэтому ее часто используют в качестве удобной модели для изучения биологических механизмов старения человека в целом [1]. Увеличение продолжительности жизни и стабильный возраст наступления менопаузы привели к тому, что современные женщины все большее число лет проводят в постменопаузе. К непосредственным эффектам связанного с менопаузой снижения уровня половых гормонов относят потерю фертильности, вазомоторные симптомы, а к долговременным – остеопороз, сердечно-сосудистые заболевания (ССЗ) и старение кожи, являющееся предметом выраженного дискомфорта, особенно для женщин [2, 3].

 

Healthy aging (anti-aging) involves the prevention of illness and disability, keeping mental and physical activity in tip-top shape, maintaining the meaning and purpose of life. Women refuse to age and want to look younger as long as possible. The skin is the only organ which condition can be assessed visually, a peculiar mirror that reflects age-dependent changes that take place in the human body and the state of health as a whole. All regular age-dependent changes that occur at the cellular level happen in the skin, therefore, it is often used as a convenient model for studying the biological mechanisms of human aging as a whole [1]. An increase in life expectancy and a stable age of menopause has led to the fact that modern women spend more and more years in postmenopausal state. The direct effects of menopause-related sex hormone production slowing down include loss of fertility, vasomotor symptoms, and the long-term ones such as osteoporosis, cardiovascular disease (CVD) and skin aging, which causes marked discomfort, especially for women [2, 3].

 

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The authors declare that there are no conflicts of interest present.