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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-8-52-57</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2433</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Практика</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Practice</subject></subj-group></article-categories><title-group><article-title>К вопросу о патогенезе изолированного неинвазивного грибкового сфеноидита</article-title><trans-title-group xml:lang="en"><trans-title>To the question of the isolated noninvasive fungal sphenoiditis pathogenesis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочетков</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kochetkov</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ордян</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ordyan</surname><given-names>A. B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Луничева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lunicheva</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow StateMedical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>19</day><month>04</month><year>2018</year></pub-date><volume>0</volume><issue>8</issue><fpage>52</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кочетков П.А., Ордян А.Б., Луничева А.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Кочетков П.А., Ордян А.Б., Луничева А.А.</copyright-holder><copyright-holder xml:lang="en">Kochetkov P.A., Ordyan A.B., Lunicheva A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2433">https://www.med-sovet.pro/jour/article/view/2433</self-uri><abstract><p>Неинвазивный грибковый синусит является распространенным заболеванием верхних дыхательных путей. Заболевание может длительное время протекать бессимптомно или иметь клиническую манифестацию с преобладанием неврологической и офтальмологической симптоматики. Данная патология является абсолютно хирургическим заболеванием и успешно поддается лечению. Однако в отличие от неинвазивного грибкового поражения верхнечелюстной пазухи, когда стартовым механизмом роста мицетомы является попадание в пазуху инородного тела при стоматологических манипуляциях, патогенез изолированного грибкового сфеноидита остается дискутабельным. По аналогии высказано предположение о заносе в клиновидную пазуху при определенных условиях инородной субстанции, которая становится триггером развития грибкового тела в синусе. На основе анализа клинических случаев нами были установлены характерные клинико-анатомические особенности, которые являются определяющими в патогенезе данного заболевания и могут быть взяты за основу при дифференциальной диагностике хронического бактериального и неинвазивного грибкового сфеноидитов. Основное значение в патогенезе имеют девиации носовой перегородки, отсутствие гиперплазии носовых раковин, а также значительно увеличенный размер соустья клиновидной пазухи.</p></abstract><trans-abstract xml:lang="en"><p>Noninvasive fungal sinusitis is a widespread disease of the top respiratory tracts. The disease can proceed a long time asymptomatically or have a clinical demonstration with a dominance of a neurologic and ophthalmologic symptomatology. This pathology is surgical disease and successfully responds to treatment. However, unlike a noninvasive mycotic affection of maxillary sinus, when the starting mechanism of mitsetoma grow is invasion of foreign body after stomatologic manipulations, the pathogenesis of the isolated fungal sphenoiditis remains diskutabelny. By analogy, it is suggested about a drift into the sphenoidal sinus under certain conditions of foreign substance, which becomes the trigger of development of a fungal body in a sinus. Based on the analysis of clinical cases we established the reference cliniko-anatomic features, which are defining in a pathogenesis of this disease and can be taken as a basis at differential diagnostics chronic bacteriemic and noninvasive fungalc sphenoiditis. In a pathogenesis deviations of a nasal septum, hypoplasia of nasal turbinates and also considerably oversize of the ostium of a sphenoid sinus have a basic meaning.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>неинвазивный грибковый сфеноидит</kwd><kwd>мицетома клиновидной пазухи</kwd><kwd>грибковое тело</kwd></kwd-group><kwd-group xml:lang="en"><kwd>noninvasive fungal sphenoiditis</kwd><kwd>mitsetoma of sphenoidal sinus</kwd><kwd>fungal body</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Морозова О.В. Диагностика и лечение различных форм грибкового синусита. СПб.: Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи, 2012.</mixed-citation><mixed-citation xml:lang="en">Morozova OV. Diagnosis and treatment of varieties of fungal sinusitis, St. Petersburg. 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