medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2015-9-92-99medsovet-252Research ArticleАКУШЕРСТВОOBSTETRICSДостижения и риски применения фолатов вне и во время беременностиAchievements and risks of folate use during and not in pregnancyПустотинаО. А.PustotinaO. A.noemail@neicon.ruРоссийский университет дружбы народов, МоскваРоссияGynecology and Reproductive Medicine of the People's Friendship University of RussiaRussian Federation201530122015099299Copyright © Пустотина О.А., 20152015Пустотина О.А.Pustotina O.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/252

90% популяции имеет дефицит фолатов, который связан как с недостаточным потреблением фолатсо-держащих пищевых продуктов, так и с нарушением функции ферментов фолатного цикла. Вследствие высокой распространенности среди населения генетических полиморфизмов ферментов фолатного цикла патогенетически обоснованным является применение поливитаминно-минерального комплекса, содержащего фолаты в биологически активной форме.

90% of the population have folate deficiency, which is associated with both inadequate intake of folate-containing food and impaired function of the folate cycle enzymes. Due to a high prevalence among the population of genetic polymorphisms of the folate cycle enzymes, the use of a multivitamin-mineral complex containing folates in a biologically active form is pathogenetically justified.

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The authors declare that there are no conflicts of interest present.