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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-11-175-180</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2522</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Школа педиатра</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>School for pediatrician</subject></subj-group></article-categories><title-group><article-title>Кишечная микробиота: современные доказательные данные эффективности применения Lactobacillus rhamnosus GG и Bifidobacterium longum в практике педиатра</article-title><trans-title-group xml:lang="en"><trans-title>Intestinal microbiota: updated evidence-based data on the efficacy of Lactobacillus rhamnosus GG and Bifidobacterium longum in pediatric practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горелов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorelov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>профессор, чл.-корр. РАН</p></bio><bio xml:lang="en"><p>Prof., Corr. Member of RAS</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каннер</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kanner</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимов</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Maximov</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н.</p></bio><bio xml:lang="en"><p>MD</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермолаева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermolaeva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD in medicine</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вознесенская</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Voznesenskaya</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дадашева</surname><given-names>К. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dadasheva</surname><given-names>K. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «Центральный научно-исследовательский институт эпидемиологии Роспотребнадзора», Москва;&#13;
ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology of Rospotrebnadzor, Moscow;&#13;
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФБУН «Центральный научно-исследовательский институт эпидемиологии Роспотребнадзора», Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology of Rospotrebnadzor, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Казанская государственная медицинская академия – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical Academy – Branch of the Russian Medical Academy of Continuing Postgraduate Education of the Ministry&#13;
of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.F. Vladimirsky Moscow Regional Research Clinical Institute, State Budget Health Institution</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>16</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>11</issue><fpage>175</fpage><lpage>180</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Горелов А.В., Каннер Е.В., Максимов М.Л., Ермолаева А.С., Вознесенская А.А., Дадашева К.Н., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Горелов А.В., Каннер Е.В., Максимов М.Л., Ермолаева А.С., Вознесенская А.А., Дадашева К.Н.</copyright-holder><copyright-holder xml:lang="en">Gorelov A.V., Kanner E.V., Maximov M.L., Ermolaeva A.S., Voznesenskaya A.A., Dadasheva K.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2522">https://www.med-sovet.pro/jour/article/view/2522</self-uri><abstract><p>В статье представлены современные данные о составе, становлении и роли кишечной микробиоты. Показана взаимосвязь между изменениями микробиоты кишечника и формированием различных форм патологии. Приведены данные об эффективности профилактического и лечебного действия пробиотических штаммов, наиболее часто используемых в практике педиатра.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The article presents updated data on the composition, formation and role of the intestinal microbiota. It shows the relationship between changes in the intestinal microbiota and the formation of various forms of pathology. Data on the effectiveness of the prophylactic and therapeutic effect of probiotic strains, most often used in paediatric practice, are provided.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>кишечная микробиота</kwd><kwd>пробиотики</kwd><kwd>Lactobacillus rhamnosus GG</kwd><kwd>Bifidobacterium longum</kwd><kwd>эффективность</kwd><kwd>безопасность</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>intestinal microbiota</kwd><kwd>probiotics</kwd><kwd>Lactobacillus rhamnosus GG</kwd><kwd>Bifidobacterium longum</kwd><kwd>efficacy</kwd><kwd>safety</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Clemente JC, Ursell LK, Parfrey LW, Knight R. The impact of the gut microbiota on human health: an integrative view. 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