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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-12-40-43</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2562</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРОНХОПУЛЬМОНОЛОГИЯ, ЛОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRONCHOPULMONOLOGY, ENT</subject></subj-group></article-categories><title-group><article-title>Топические деконгестанты. Мифы и реальность</article-title><trans-title-group xml:lang="en"><trans-title>Topical decongestants: myth and reality</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирошниченко</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Miroshnichenko</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овчинников</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovchinnikov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I.Yevdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>24</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>12</issue><fpage>40</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мирошниченко Н.А., Овчинников А.Ю., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Мирошниченко Н.А., Овчинников А.Ю.</copyright-holder><copyright-holder xml:lang="en">Miroshnichenko N.A., Ovchinnikov A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2562">https://www.med-sovet.pro/jour/article/view/2562</self-uri><abstract><p>Носовое дыхание играет важную роль в респираторной функции, которая обеспечивает поступление в организм человека необходимого количества воздуха. При возникновении назальной обструкции дыхание осуществляется главным образом через рот, и все многочисленные функции носа нарушаются. Это приводит вначале к функциональным особенностям, а  затем к морфологическим и структурным изменениям. Наиболее популярными препаратами для быстрой борьбы с назальной обструкцией являются топические деконгестанты, которые обладают наиболее сильным и быстрым эффектом. Основные назальные деконгестанты можно разделить на две группы – симпатомиметические амины: первичные алифатические фенольные и нефенольные соединения, а также имидазолиновые производные. Из современных сосудосуживающих препаратов хорошо себя зарекомендовал Отривин® комплекс. В состав препарата входит ксилометазолин и ипратропия бромид. Применение его строго по инструкции и не более 15 дней гарантирует отсутствие развития тяжелых местных и системных осложнений.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>Nasal breathing plays an important role in the respiratory function, which ensures that a person consumes appropriate levels of air. Nasal obstruction causes a person to consume air mainly through the mouth, which impairs the numerous functions of the nose. This leads first to functional abnormalities, and then to morphological and structural changes. Topical decongestants that have the strongest and fastest effect are the most popular drugs to manage rapidly nasal obstruction. The main nasal decongestants can be divided into two groups: sympathomimetic amines: primary aliphatic, phenolic and non-phenolic compounds, as well as imidazoline derivatives. Among modern vasoconstrictive drugs, Otrivin® complex showed good results. The drug contains xylometazoline and ipratropium bromide. Application of this drug strictly according to the instructions and for no more than 15 days guarantees the absence of severe local and systemic complications.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>ринит</kwd><kwd>заложенность носа</kwd><kwd>деконгестанты</kwd><kwd>Отривин® комплекс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rhinitis</kwd><kwd>nasal congestion</kwd><kwd>decongestants</kwd><kwd>Otrivin® complex</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Passali D, Buccellam G, Vetuschi A, Bellussi L. Nasal vascularization: experiences using the microcorrosion technique in human foetuses. Rhinology, 1992, 30(2): 81-88. The paper is the first and, to the authors’ knowledge unique article describing in details the complex nasal vascularisation.</mixed-citation><mixed-citation xml:lang="en">Passali D, Buccellam G, Vetuschi A, Bellussi L. 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