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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-12-182-184</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2585</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTANT</subject></subj-group></article-categories><title-group><article-title>Комплексная оценка больных хронической обструктивной болезнью легких с помощью многокомпонентного индекса ADO и индекса коморбидности Charlson</article-title><trans-title-group xml:lang="en"><trans-title>Comprehensive assessment of patients with chronic obstructive pulmonary disease by means of multicomponent ADO index and Charlson comorbidity index</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочетова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kochetova</surname><given-names>E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО «Петрозаводский государственный университет»<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>29</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>12</issue><fpage>182</fpage><lpage>184</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кочетова Е.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Кочетова Е.В.</copyright-holder><copyright-holder xml:lang="en">Kochetova E.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2585">https://www.med-sovet.pro/jour/article/view/2585</self-uri><abstract><p>Целью настоящего исследования было изучение индекса ADO и индекса коморбидности Charlson у больных хронической обструктивной болезнью легких (ХОБЛ). Материал и методы: обследованы 207 больных ХОБЛ с длительным стажем курения. Исследование ФВД проводили на многомодульной установке типа MasterLab/Jaeger. У больных определяли индексы ADO и Charlson. Результаты: показатели индекса ADO возрастали по мере усугубления стадии ХОБЛ. Минимальный уровень индекса ADO наблюдался у пациентов с ХОБЛ 2-й стадии – 2,23 ± 0,88. При 3-й стадии ХОБЛ ADO составлял 5,05 ± 1,19, при 4-й стадии ХОБЛ – 7,0 ± 1,0. Установлена корреляционная связь между индексом ADO и индексом коморбидности Charlson – r 0,7, p &lt; 0,005. Выявлена корреляционная связь между индексом ADO и ЖЕЛ – r -0,57, p &lt; 0,05; между индексом ADO и ERV – r -0,63, p &lt; 0,05.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The purpose of this study was to investigate the ADO index, and index of comorbidity of Charlson in patients with chronic obstructive pulmonary disease (COPD). Materials and methods: 207 patients with chronic obstructive pulmonary disease (COPD) were observed. The investigated group was made by the patients having the long experience of smoking. Research of function of external breath was studied with multimodular installation of type «Master-Lab/Jaeger». Patients were determined the index ADO and of comorbidity of Charlson. Results: The index ADO increased with stage of COPD, minimum of level ADO was observed in patients with COPD 2 stage 2,23 ± 0,88, in patients with 3 stage COPD ADO was 5,05 ± 1,19, 4 stages of COPD 7,0 ± 1,0. The correlation coefficient between ADO index and and index of comorbidity Charlson was -0,71, p &lt;0,005. The correlation coefficient between ADO and VC was -0,57, p &lt;0,05, between ADO and ERV was -0,63, p &lt;0,05.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>ХОБЛ</kwd><kwd>индекс ADO</kwd><kwd>индекс коморбидности Charlson</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COPD</kwd><kwd>the index ADO</kwd><kwd>the index of comorbidity Charlson</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Карнаушкина М.А., Федосенко С.В., Сазонов А.Э., Петров В.А., Ваколюк Р.М., Дворецкий Л.И., Огородова Л.М. Сложности прогнозирования течения ХОБЛ как вызов современной клинической пульмонологии. Архив внутренней медицины, 2016, 4: 14-20</mixed-citation><mixed-citation xml:lang="en">Karnaushkina MA, Fedosenko SV, Sazonov AE, Petrov VA, Vakolyuk RM, Dvoretsky LI, Ogorodova LM. The diffi culties of predicting the course of COPD as a challenge to modern clinical pulmonology. Arkhiv Vnutrennei Meditsiny, 2016, 4: 14-20.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Nishimura M, Makita H, Nagai K et al. Annual change in pulmonary function and clinical phenotype in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 2012, 185: 44-52.</mixed-citation><mixed-citation xml:lang="en">Nishimura M, Makita H, Nagai K et al. Annual change in pulmonary function and clinical phenotype in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 2012, 185: 44-52.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Horita N, Koblizek V, Plutinsky M et al. Chronic obstructive pulmonary disease prognostic score: A new index. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2016 Jun, 160(2): 211-218.</mixed-citation><mixed-citation xml:lang="en">Horita N, Koblizek V, Plutinsky M et al. Chronic obstructive pulmonary disease prognostic score: A new index. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2016 Jun, 160(2): 211-218.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">O’Donnell DE. Dynamic lung hyperinﬂ ation and its clinical implication in COPD. Rev Mal Respir, 2009, 26: 19-29.</mixed-citation><mixed-citation xml:lang="en">O’Donnell DE. Dynamic lung hyperinﬂ ation and its clinical implication in COPD. Rev Mal Respir, 2009, 26: 19-29.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">O’Donnell DE. Hyperinﬂ ation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Proc Am Thorac Soc, 2006, 3: 180-184.</mixed-citation><mixed-citation xml:lang="en">O’Donnell DE. Hyperinﬂ ation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Proc Am Thorac Soc, 2006, 3: 180-184.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gatta D, Aliprandi G, Pini L, Zanardini A, Fredi M, Tantucci C. Dynamic pulmonary hyperinﬂ ation and low grade systemic inﬂ ammation in stable COPD patients. Eur Rev Med Pharmacol Sci, 2011 Sep, 15(9): 1068-1073.</mixed-citation><mixed-citation xml:lang="en">Gatta D, Aliprandi G, Pini L, Zanardini A, Fredi M, Tantucci C. Dynamic pulmonary hyperinﬂ ation and low grade systemic inﬂ ammation in stable COPD patients. Eur Rev Med Pharmacol Sci, 2011 Sep, 15(9): 1068-1073.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Charlson ME, Pompei P, Ales KL et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis, 1987, 40: 373-383.</mixed-citation><mixed-citation xml:lang="en">Charlson ME, Pompei P, Ales KL et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis, 1987, 40: 373-383.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
