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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-13-34-38</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2599</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Контрацепция</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Contraception</subject></subj-group></article-categories><title-group><article-title>Эстрадиола валерат и диеногест в гормональной контрацепции приемлемость и эффективность в реальной клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>Estradiol valerate and dienogest in hormonal contraception. Acceptability and effectiveness in real clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Довлетханова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Dovletkhanova</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., старший научный сотрудник научно-поликлинического отделения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прилепская</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Prilepskaya</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, руководитель научно-поликлинического отделения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kulakov National Medical Research Centre for Obstetrics, Gynaecology and Perinatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2018</year></pub-date><volume>0</volume><issue>13</issue><fpage>34</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Довлетханова Э.Р., Прилепская В.Н., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Довлетханова Э.Р., Прилепская В.Н.</copyright-holder><copyright-holder xml:lang="en">Dovletkhanova E.R., Prilepskaya V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2599">https://www.med-sovet.pro/jour/article/view/2599</self-uri><abstract><p>В настоящее время комбинированные гормональные контрацептивы являются одним из наиболее эффективных методов предотвращения наступления нежелательной беременности. Они обеспечивают высокую контрацептивную надежность, доступность и простоту применения, обратимость эффектов, безопасность применения. Современные гормональные контрацептивы оказывают дополнительное лечебное и профилактическое действие при различных состояниях. В результате ряда тщательных научных исследований был разработан инновационный комбинированный оральный контрацептив Клайра®. Представлен опыт применения комбинированного гормонального контрацептива, содержащего эстрадиола валерат и диеногест, Клайра® (Э2В/ДНГ). Результаты наблюдения показали высокую контрацептивную эффективность, приемлемость и переносимость.</p></abstract><trans-abstract xml:lang="en"><p>The combined hormonal contraceptives are now one of the most effective methods of preventing unwanted pregnancies. They provide high contraceptive reliability, accessibility and ease of use, reversibility of effects, safety of use. Modern hormonal contraceptives provide additional therapeutic and prophylactic effects in various conditions. A new combined oral contraceptive Qlaira® was developed in the course of thorough scientific studies. The article presents the experience in using a combined hormonal contraceptive containing estradiol valerate and dienogest – Qlaira® (E2V/DNG). The observations showed high contraceptive effectiveness, acceptability and tolerability.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>контрацепция</kwd><kwd>комбинированные гормональные контрацептивы</kwd><kwd>эстрадиола валерат и диеногест – Клайра® (Э2В/ДНГ)</kwd><kwd>меноррагия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>contraception</kwd><kwd>combined hormonal contraceptives</kwd><kwd>estradiol valerate and dienogest – Qlaira® (E2V/DNG)</kwd><kwd>menorrhagia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Руководство по амбулаторно-поликлинической помощи в акушерстве и гинекологии. Под ред. В.Н. Серова, Г.Т. Сухих, В.Н. Прилепской, В.Е. Радзинского. 3-е изд., перераб. и доп. М.: ГЭОТАР-Медиа, 2016: 885-894.</mixed-citation><mixed-citation xml:lang="en">Guidelines for outpatient care in obstetrics and gynecology. 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