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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-14-78-82</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2656</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОМОРБИДНЫЕ ЗАБОЛЕВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COMORBID DISEASES</subject></subj-group></article-categories><title-group><article-title>Фармакологические подходы к лечению сочетанной функциональной патологии (билиарной и кишечника)</article-title><trans-title-group xml:lang="en"><trans-title>Pharmacological approaches to the treatment of combined functional pathology (biliary and intestinal tract)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минушкин</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Minushkin</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой гастроэнтерологии,</p><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ДПО «ЦГМА» Управления делами Президента РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of Administrative Directorate of the President of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>10</day><month>10</month><year>2018</year></pub-date><volume>0</volume><issue>14</issue><fpage>78</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Минушкин О.Н., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Минушкин О.Н.</copyright-holder><copyright-holder xml:lang="en">Minushkin O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2656">https://www.med-sovet.pro/jour/article/view/2656</self-uri><abstract><p>В статье представлены данные по новой классификации функциональных расстройств согласно Римским критериям IV. Особое внимание уделено сочетанной функциональной патологии – синдрому перекреста. Среди функциональных расстройств наиболее распространен вариант сочетания функциональных билиарных расстройств (ФБР) и синдром раздраженного кишечника (СРК). Рассмотрена тактика консервативного лечения  – выбор миотропного спазмолитика. Проанализированы результаты собственного исследования по эффективности препарата Ниаспам в лечении абдоминальной боли, метеоризма и нарушения стула у пациентов с ФБР и СРК. </p></abstract><trans-abstract xml:lang="en"><p>The article presents data on a new classification of functional disorders according to Rome IV criteria. Particular attention is given to the combined functional pathology - the overlap syndrome. The combination of functional biliary disorders (PBD) and irritable bowel syndrome (IBS) is the most common functional disorder. The tactic of conservative treatment - the choice of myotropic antispasmodic is considered. The analysis of the results of our own study of the efficacy of Niaspam in the treatment of abdominal pain, flatulence and stool disorders in patients with PBD and IBS are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром перекреста</kwd><kwd>функциональные билиарные расстройства</kwd><kwd>синдром раздраженного кишечника</kwd><kwd>лечение</kwd><kwd>спазмолитики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>overlap syndrome</kwd><kwd>functional biliary disorders</kwd><kwd>irritable bowel syndrome</kwd><kwd>treatment</kwd><kwd>antispasmodic drugs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Miyachi K. et al. Clinical studies on overlap syndrome. Ryumachi. 1973; 13(3): 289-93. Kim H.G. et al. G-Protein Beta3 Subunit C825T Polymorphism in Patients With Overlap Syndrome of Functional Dyspepsia and Irritable Bowel Syndrome. 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