medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2018-15-8-17medsovet-2666Research ArticleХроническая обструктивная болезнь легкихChronic obstructive pulmonary diseaseПрофилактика обострений хронической обструктивной болезни легких. В фокусе – двойные комбинации бронхолитиковPrevention of copd exacerbations. Focus on dual bronchodilatorsАрхиповВ. В.ArkhipovV. V.

Архипов Владимир Владимирович – доктор медицинских наук, профессор кафедры клинической фармакологии и терапии.

Москва

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияRussian Medical Academy of Continuing Postgraduate Education, Federal State Budgetary Educational Institution of Further Professional Education of the Ministry of Health of RussiaRussian Federation201811102018015817Copyright © Архипов В.В., 20182018Архипов В.В.Arkhipov V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2666

Обострения ХОБЛ возникают практически у всех больных, а у половины пациентов в РФ (52%) за год обострения отмечаются два или более раза либо требуют госпитализации больного в стационар. В основе обострения ХОБЛ лежит острое усиление процессов воспаления в дыхательных путях больного под воздействием ряда факторов. Современная фармакотерапия предоставляет врачу целый ряд опций для снижения числа обострений. В настоящем обзоре представлены данные, свидетельствующие о максимальном снижении риска обострений при назначении комбинации тиотропий/олодатерол или тройной терапии.

COPD exacerbations occur in almost all patients, and half of patients in the Russian Federation (52%) have two or more exacerbations per year or require urgent admission to hospital. COPD exacerbations come from increased acute inflammation in the respiratory tract of a patient under the influence of many factors. Modern pharmacotherapy provides the physician with several options in reducing the number of exacerbations. This review provides evidence about the maximum reduction in exacerbation risk due to the administration of tiotropium/olodaterol combination or triple therapy.

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The authors declare that there are no conflicts of interest present.