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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-15-28-37</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2668</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Хроническая обструктивная болезнь легких</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Chronic obstructive pulmonary disease</subject></subj-group></article-categories><title-group><article-title>Новые возможности фармакотерапии хронической обструктивной болезни легких</article-title><trans-title-group xml:lang="en"><trans-title>New possibilities of pharmacotherapy for chronic obstructive pulmonary disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синопальников</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinopalnikov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синопальников Александр Игоревич – доктор медицинских наук, профессор, завкафедрой пульмонологии.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романовских</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanovskikh</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Романовских Анна Геннадьевна – кандидат медицинских наук, доцент.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоцерковская</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Belotserkovskaya</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белоцерковская Юлия Геннадьевна – кандидат медицинских наук, доцент.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России<country>Россия</country></aff><aff xml:lang="en">Russian Medical Academy of Continuing Postgraduate Education of the Ministry of Health of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>11</day><month>10</month><year>2018</year></pub-date><volume>0</volume><issue>15</issue><fpage>28</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Синопальников А.И., Романовских А.Г., Белоцерковская Ю.Г., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Синопальников А.И., Романовских А.Г., Белоцерковская Ю.Г.</copyright-holder><copyright-holder xml:lang="en">Sinopalnikov A.I., Romanovskikh A.G., Belotserkovskaya Y.G.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2668">https://www.med-sovet.pro/jour/article/view/2668</self-uri><abstract><p>Ведущей терапевтической стратегией при лечении хронической обструктивной болезни легких (ХОБЛ) до настоящего времени остается применение бронходилататоров (БД), при этом наиболее перспективным представляется назначение фиксированных комбинаций длительно действующих бронхорасширяющих препаратов. Вместе с тем активно обсуждаются и вопросы противовоспалительной терапии ХОБЛ, в первую очередь целесообразность широкого использования фиксированных комбинаций ингаляционных глюкокортикостероидов (ИГКС) с длительно действующими β2-агонистами (ДДБА). Последние годы характеризуются появлением на фармацевтическом рынке значительного числа новых БД, противовоспалительных препаратов и их комбинаций. Роль и место новых препаратов в лечении ХОБЛ стабильного течения рассматриваются в представленной статье.</p></abstract><trans-abstract xml:lang="en"><p>The use of bronchodilators (DB) remains up to the present day the leading therapeutic strategy for the treatment of chronic obstructive pulmonary disease (COPD), in which case administration of fixed-dose combinations of long-acting bronchodilators seem the most promising. At the same time, the issues of anti-inflammatory therapy of COPD are also actively discussed, first of which is feasibility for the wide use of fixed-dose combinations of inhaled glucocorticosteroids (IHGC) with long-acting β2-agonists (LABA). Recent years are characterized by the launch of a significant number of new BDs, anti-inflammatory drugs and their combinations to the pharmaceutical market. The article considers the role and place of new drugs in the treatment of COPD having a stable course.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь легких</kwd><kwd>фармакотерапия</kwd><kwd>вилантерол/умеклидиний</kwd><kwd>вилантерол/ флутиказона фуроат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic obstructive pulmonary disease</kwd><kwd>pharmacotherapy</kwd><kwd>vilenterol/umeclidinium</kwd><kwd>vilantherol / fluticasone furoate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Diaz-Guzman E, Mannino DM. Epidemiology and prevalence of chronicobstructive pulmonary disease. Clin Chest Med, 2014, 35(1): 7–16.</mixed-citation><mixed-citation xml:lang="en">Diaz-Guzman E, Mannino DM. Epidemiology and prevalence of chronicobstructive pulmonary disease. 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