medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2018-15-70-75medsovet-2673Research ArticleБронхиальная астмаBronchial asthmaТяжелая эозинофильная астма: терапевтический потенциал РеслизумабаSevere eosinophilic asthma: therapeutic potential of ReslizumabФассаховР. С.FassakhovR. S.Институт фундаментальной медицины и биологии Казанского (Приволжского) федерального университетаРоссияInstitute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal UniversityRussian Federation2018111020180157075Copyright © Фассахов Р.С., 20182018Фассахов Р.С.Fassakhov R.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2673

В обзоре рассматриваются проблемы, связанные с лечением больных с тяжелой резистентной к терапии бронхиальной астмой: распространенность, социально-экономический ущерб, влияние на качество жизни. Детально обсуждается фенотип бронхиальной астмы с эозинофильным воспалением, частота встречаемости, клинические особенности и современные подходы к терапии, включая применение препарата моноклональных антител против интерлейкина-5 реслизумаба.

The review discusses the problems associated with the treatment of patients with severe resistant to therapy asthma: prevalence, socio-economic burden, impact on quality of life. The phenotype of bronchial asthma with eosinophilic inflammation, frequency of occurrence, clinical features, and modern approaches to therapy are discussed in detail, including the use of a drug of monoclonal antibodies against interleukin 5-reslizumab.

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The authors declare that there are no conflicts of interest present.